Results 81 to 90 of about 896,611 (230)

KDAC6 alters cell morphology and motility through positive and negative modulation of F‐actin distribution

FEBS Open Bio, EarlyView.
KDAC6 has been associated with cell motility and actin structures, but specific domain contributions are not established. The two catalytic domains have differential effects on motility and F‐actin regulation, affecting cortical F‐actin density, motility, stress fibers, and cell spreading.
Taylor V. Joseph, Andrea B. Pham, Kiara E. Bornes, Razan H. Hammad, Chelsea A. Rousseve‐Ross, Thomas M. Huckaba, Terry J. Watt, Tasha B. Toro   +7 more
wiley   +1 more source

Basic principals of the tiltrotors flight control system architecture and algorithms

Научный вестник МГТУ ГА
This study describes the main structure and algorithm development principles of flight control systems for tiltrotor aircraft using the example of rotary-wing aircraft V-22 Osprey and AW609.
M. I. Myasnikov, I. R. Ilyin
doaj   +1 more source

Handling qualities studies into the interaction between active sidestick parameters and helicopter response types

, 2013
Active inceptors offer great potential for improving the handling qualities of fly-by-wire rotorcraft. In a cooperative research effort, the DLR Institute of Flight Systems in Germany and the U.S.
von Grünhagen, Wolfgang, Lantzsch, Robin, Lusardi, Jeff A., Schönenberg, Thorben, Lee, David, Fischer, Heiko   +5 more
core   +1 more source

Identification of (20R)‐protopanaxadiol from Panax ginseng as a novel anti‐SARS‐CoV‐2 compound

FEBS Open Bio, EarlyView.
We established a noninfectious BAC‐based SARS‐CoV‐2 replicon that enables antiviral screening under BSL‐2 conditions. Using this platform, we screened 373 food‐derived compounds and identified (20R)‐protopanaxadiol from Panax ginseng as a novel inhibitor of SARS‐CoV‐2 RNA replication, highlighting the value of safe replicon systems for antiviral ...
Midori Takeda, Natsue Maezono, Rina Uchikoshi, Nobuyuki Kato, Masanori Ikeda   +4 more
wiley   +1 more source

Flight Tests of Scaled Demonstrator for General Aviation Aircraft Concept

Engineering Proceedings
The present work investigates the flight characteristics and handling qualities of the novel aircraft concept “HyBird” through multiple scaled flight experiments.
Thorben Hammer, Stefanie de Graaf, Anne Treder   +2 more
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

FEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen, Robin Romein, Willy A. M. van den Berg, Simon Lindhoud, Jan Willem Borst, Carlo P. M. van Mierlo   +5 more
wiley   +1 more source

Crises and Electoral Accountability: How Do Individual Characteristics of Crises Affect Performance and Responsibility Evaluations among Voters?

Government and Opposition
How do voters react to the individual characteristics of crises following events such as pandemics or floods? In the aftermath of crises following such events, governments may find they are sanctioned by voters, because the crises can provide voters with
Jan Berz
doaj   +1 more source

Protocol for quantifying miRNA trafficking across the endosomal membrane

FEBS Open Bio, EarlyView.
An in vitro protocol measures miRNA uptake into endosomes isolated from mammalian cell extracts, which are free of subcellular contaminants. Performed at 37 °C in the presence of ATP, it ensures the import of single‐stranded miRNA into the endosomal lumen.
Syamantak Ghosh, Kamalika Mukherjee, Suvendra N. Bhattacharyya   +2 more
wiley   +1 more source

Stomata: plant pores connecting preharvest conditions to postharvest quality

Journal of Agriculture and Food Research
Stomata are microscopic pores on the surface of leaves that play an important role in regulating gas exchange and water loss both before and after harvest.
Shafieh Salehinia, Sasan Aliniaeifard, Philip Wiredu Addo, Sarah MacPherson, Kam Hammad, Mark Lefsrud   +5 more
doaj   +1 more source

Dual native G‐quadruplex folding is associated with chromatin looping at the MYC locus

FEBS Open Bio, EarlyView.
BG4‐detectable G‐quadruplex (G4) in HaCaT and NHEK keratinocytes identified folded and unfolded G4s enriched at promoters/TSSs and active enhancers, whereas unfolded G4s also overlapped weak/poised enhancers. At MYC–PVT1, 3C‐qPCR detected enhancer–promoter looping only when G4s were simultaneously folded at both regulatory elements under native ...
Dieila Giomo de Lima, Gustavo Narvaes Guimarães, Emilyane de Oliveira Santana Amaral, Bianca Caroline Figueiredo Bianco, Manuel Jara‐Espejo, Sérgio Roberto Peres Line, Ana Paula de Souza, Aline Cristiane Planello   +7 more
wiley   +1 more source