Results 61 to 70 of about 14,024 (303)

Comparison between Digital and Paper Handwriting—A Contribution to Graphoscopic Analysis

Medical Sciences Forum, 2023
The growing development of new technologies and the evolution of communication devices has led the world’s population to gradually replace traditional writing on paper and pen with digital handwriting. This shift in writing instruments and media presents
Vlad Tatarescu, Daniela Eusébio, Mariana M. Louro, Alexandra Bernardo   +3 more
doaj   +1 more source

Developmental programmes drive cellular plasticity, disease progression and therapy resistance in lung adenocarcinoma

Molecular Oncology, EarlyView.
This study shows that lung adenocarcinomas exploit developmental branching morphogenesis to acquire a therapy resistant basal‐like tumour cell state. This process was found to be regulated by combined TP53 loss‐of‐function and type‐I interferon signalling, identifying a novel axis for biomarker and therapeutic target discovery.
Kamila J Bienkowska, Stephany Gallardo, Nur S. Zainal, Leena Arora, Matthew Ellis, Maria‐Antoinette Lopez, Judith Austine, Sai Pittla, Serena J Chee, Aiman Alzetani, Emily C Shaw, Christian H Ottensmeier, Gareth J Thomas, Christopher J Hanley   +13 more
wiley   +1 more source

International Conference on Frontiers in Handwriting Recognition (ICFHR 2010) – Competitions Overview

, 2010
The great success and high number of participants in pattern recognition related competitions last years show an important improvement of recognition and classification approaches.
Michael Blumenstein, Haikal El Abed, Abed, Haikal, Margner, Volker, Volker Margner, Blumenstein, Michael   +5 more
core   +1 more source

Automated FRAP microscopy for high‐throughput analysis of protein dynamics in chromatin organization and transcription

FEBS Open Bio, EarlyView.
RoboMic is an automated confocal microscopy pipeline for high‐throughput functional imaging in living cells. Demonstrated with fluorescence recovery after photobleaching (FRAP), it integrates AI‐driven nuclear segmentation, ROI selection, bleaching, and analysis.
Selçuk Yavuz, Bart Geverts, Johan A. Slotman, Andrea Sacchetti, Stefan Prekovic, Martin E. van Royen, Adriaan B. Houtsmuller   +6 more
wiley   +1 more source

Cognitive impairment assessment through handwriting (COGITAT) score: a novel tool that predicts cognitive state from handwriting for forensic and clinical applications

Frontiers in Psychology
IntroductionHandwriting deteriorates proportionally to the writer’s cognitive state. Such knowledge is of special importance in the case of a contested will, where dementia of the testator is claimed, but medical records are often insufficient to decide ...
Maurizio Balestrino, Maurizio Balestrino, Andrea Brugnolo, Andrea Brugnolo, Nicola Girtler, Nicola Girtler, Matteo Pardini, Matteo Pardini, Cristiano Rizzetto, Paolo Alessandro Alì, Leonardo Cocito, Irene Schiavetti   +11 more
doaj   +1 more source

Teachers’ perspectives on handwriting and collaborative intervention for children with Autistic Spectrum Disorder [PDF]

Irish Journal of Occupational Therapy, 2017
Purpose - This study aims to investigate teacher perspectives on teaching handwriting to children with autistic spectrum disorder (ASD) and collaboration with occupational therapists.
Therese McNamee, Sandra Patton
doaj   +1 more source

A light‐triggered Time‐Resolved X‐ray Solution Scattering (TR‐XSS) workflow with application to protein conformational dynamics

FEBS Open Bio, EarlyView.
Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei, Fredrik Orädd, Konstantinos Magkakis, Magnus Andersson   +3 more
wiley   +1 more source

Reliability and validity of Handwriting Test for Preschool Children (HT-PRE): A new tool to assess the handwriting ability of preschool children aged 5-6 years old in Mainland China.

PLoS ONE, 2020
BACKGROUND:Handwriting ability is related to many neuronal functions, such as visual-perceptual skills, orthographic coding, motor planning and execution, kinesthetic feedback and visual-motor coordination.
Qin Hong, Bei Jiang, Qu Xu, Lei Zhang, Jiaxin Ou, Qingyu Zhang, Nan Li, Jing Wang, Yachun Xie, Jing Hua, Xirong Guo, Meiling Tong, Xia Chi   +12 more
doaj   +1 more source

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

FEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong, Yuhei Hosokawa, Lars Oliver Essen, Manuel Maestre‐Reyna   +3 more
wiley   +1 more source