Delayed angiopoietin‐2 blockade reduces influenza‐induced lung injury and improves survival in mice
Angiopoietin‐2 (Ang‐2) is a key prognostic marker and potential mediator of Acute respiratory distress syndrome, yet it is unknown whether inhibiting Ang‐2 signaling at its receptor Tie‐2 can reduce viral lung injury after it begins. Here we demonstrate that delayed antagonism of Ang‐2 in mice with severe influenza pneumonia improves survival, gas ...
Jeffrey E. Gotts +9 more
wiley +1 more source
Microbiological and epidemiological review of Hantavirus: A Review
Hantaviruses are rodent viruses that have a world-wide distribution. Rodents and insectivores act as asymptomatic, chronic, persistently infected carrier hosts, whereas humans are dead end hosts and may exhibit symptoms after an incubation period of ...
Hardi Marif, Kwestan Ali
doaj +1 more source
From Norovirus to Andes Hantavirus: Indirect Viral Transmission and Emerging Prevention Strategies for Cruise Ship and Confined Environments. [PDF]
ABSTRACT Cruise ships and other confined travel settings remain highly vulnerable to infectious disease outbreaks. During 2025–2026, multiple norovirus outbreaks and the rare Andes hantavirus outbreak associated with the MV Hondius cruise highlighted the continuing public health challenges posed by both highly transmissible enteric viruses and emerging
Urmi UL, Willcox MDP.
europepmc +2 more sources
Proteinuria in Hantavirus Cardiopulmonary Syndrome: A Frequent Finding Linked To Mortality [PDF]
To determine the relative frequency and prognosis value of proteinuria in hantavirus cardiopulmonary syndrome (HCPS) due to Andes virus.This observational analytical study prospectively obtained data from patients admitted to 12 health centers in nine Chilean cities between 2001 and 2018.
Lopez, Rene +7 more
openaire +4 more sources
Potential Renal Sequelae in Survivors of Hantavirus Cardiopulmonary Syndrome [PDF]
Although other hantaviruses are associated with renal manifestations, hantavirus cardiopulmonary syndrome (HCPS) has not been associated with such sequelae. The HCPS survivors were prospectively evaluated for renal complications. Subjects underwent yearly evaluation, laboratory studies, and 24-hour urine collection. Thirty subjects were evaluated after
Steven A, Pergam +5 more
openaire +2 more sources
Hantavirus cardiopulmonary syndrome: a report of two cases [PDF]
Infection with hantavirus, from the family Bunyaviridae, causes hantavirus cardiopulmonary syndrome (HCPS) in the Americas. This highly lethal anthropozoonosis afflicts preferentially individuals in rural areas and is transmitted by aerosol of excreta from infected wild rodents.
Marcos Lazaro Moreli +6 more
openaire +4 more sources
INTRODUCTION: Rodent-borne hantaviruses cause severe human diseases. We completed a serological survey of hantavirus infection in rural inhabitants of Turvo County, in the southern State of Santa Catarina, Brazil, in which seropositivity for hantavirus ...
Gregório Wrublevski Pereira +7 more
doaj +1 more source
Progress on the Prevention and Treatment of Hantavirus Disease
Hantaviruses, members of the order Bunyavirales, family Hantaviridae, have a world-wide distribution and are responsible for greater than 150,000 cases of disease per year.
Rebecca L. Brocato, Jay W. Hooper
doaj +1 more source
The fundamental role of endothelial cells in hantavirus pathogenesis
Hantavirus, a genus of rodent- and insectivore-borne viruses in the family Bunyaviridae, is a group of emerging zoonotic pathogens. Hantaviruses cause hemorrhagic fever with renal syndrome (HFRS) and hantavirus cardiopulmonary syndrome (HCPS) in man ...
Jussi eHepojoki +2 more
doaj +1 more source
Potential geographic distribution of hantavirus reservoirs in Brazil.
Hantavirus cardiopulmonary syndrome is an emerging zoonosis in Brazil. Human infections occur via inhalation of aerosolized viral particles from excreta of infected wild rodents.
Stefan Vilges de Oliveira +3 more
doaj +1 more source

