Results 61 to 70 of about 1,425 (150)

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

The FASEB Journal, Volume 39, Issue 1, 15 January 2025.
The proposed model of HTNV induced PTEN degradation and PTEN‐regulated autophagy in progeny virus production: In HTNV‐infected HK‐2 cells, the viral Gc glycoprotein specifically promotes NEDD4 mediated ubiquitination and degradation of PTEN. Disruption of PTEN expression prevents autophagosome formation and increases HTNV production, whereas ...
Shuang Lu, Shuliang Chen, Yuqing Zhang, Xiaoli Mou, Mingyang Li, Shaowei Zhu, Xingyuan Chen, Tomas M. Strandin, Yale Jiang, Zhoufu Xiang, Yuanyuan Liu, Hairong Xiong, Deyin Guo, Liangjun Chen, Yirong Li, Wei Hou, Fan Luo   +16 more
wiley   +1 more source

Animal Models for the Study of Rodent‐Borne Hemorrhagic Fever Viruses: Arenaviruses and Hantaviruses

BioMed Research International, Volume 2015, Issue 1, 2015., 2015
Human pathogenic hantaviruses and arenaviruses are maintained in nature by persistent infection of rodent carrier populations. Several members of these virus groups can cause significant disease in humans that is generically termed viral hemorrhagic fever (HF) and is characterized as a febrile illness with an increased propensity to cause acute ...
Joseph W. Golden, Christopher D. Hammerbeck, Eric M. Mucker, Rebecca L. Brocato, Kevin M. Coombs   +4 more
wiley   +1 more source

Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2012
Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents.
William Marciel de Souza, Alex Martins Machado, Geonildo Rodrigo Disner, Everton Boff, Aline Rafaela da Silva Rodrigues Machado, Michelly de Padua, Luiz Tadeu Moraes Figueiredo, Gustavo Borba de Miranda   +7 more
doaj   +1 more source

A Severe Case of Hantavirus Cardiopulmonary Syndrome in a Patient Presenting as STEMI

Journal of Cardiovascular Emergencies, 2023
Hantavirus cardiopulmonary syndrome (HCPS) is a rare disease caused by Hantaviruses, that are transmitted from rodents to humans through aerosols. In some patients, HCPS can have a severe evolution, with rapid progression to respiratory distress and ...
Dobrica Diana, Udroiu Cristian Alexandru, Galrinho Ruxandra Drăgoi, Borjog Tudor, Vinereanu Dragos   +4 more
doaj   +1 more source

Unveiling the impacts of land use on the phylogeography of zoonotic New World Hantaviruses

Ecography, Volume 2024, Issue 10, October 2024.
Billions of genomic sequences and records of species occurrence are available in public repositories (e.g. National Center for Biotechnology Information, NCBI and the Global Biodiversity Information Facility, GBIF). By implementing analytical tools from different scientific disciplines, data mining these databases can aid in the global surveillance of ...
Gabriel E. García‐Peña, André V. Rubio   +1 more
wiley   +1 more source

Orthohantavirus Survey in Indigenous Lands in a Savannah-Like Biome, Brazil

Viruses, 2021
In Brazil, the first confirmed cases of hantavirus cardiopulmonary syndrome in Indigenous populations occurred in 2001. The purpose of this study was to determine the seroprevalence of orthohantavirus infections in the Utiariti Indigenous land located in
Ana Cláudia Pereira Terças-Trettel, Alba Valéria Gomes de Melo, Renata Carvalho de Oliveira, Alexandro Guterres, Jorlan Fernandes, Liana Stretch Pereira, Marina Atanaka, Mariano Martinez Espinosa, Bernardo Rodrigues Teixeira, Cibele Rodrigues Bonvicino, Paulo Sérgio D’Andrea, Elba Regina Sampaio de Lemos   +11 more
doaj   +1 more source

Hantavirus cardiopulmonary syndrome

The Southwest Journal of Medicine
Hantavirus infections are a rare group of zoonotic infections with a global distribution. In the United States the most common presentation is Hantavirus cardiopulmonary syndrome, characterized by an acute febrile illness with bilateral interstitial pulmonary infiltrates and cardio-respiratory compromise. Fatality nears 40% in U.S.
Donna Kizziar, Javier Dieguez
openaire   +1 more source

Hantavirus Infections in Light of Current Knowledge [PDF]

Mediterranean Journal of Infection, Microbes and Antimicrobials, 2017
Hantavirus is an enveloped virus with an RNA genome comprised of three negative-sense, single-stranded segments and belongs to the genus Hantavirus in family Bunyaviridae.
Selçuk KAYA
doaj   +1 more source

Sin Nombre Viral RNA Load in Patients with Hantavirus Cardiopulmonary Syndrome [PDF]

The Journal of Infectious Diseases, 2006
To address the role that viral load plays in pathogenesis in patients with hantavirus cardiopulmonary syndrome (HCPS), we quantified Sin Nombre virus S segment viral RNA in plasma samples from 27 acutely ill patients. For 6 patients, we examined viral load in matched plasma, urine, and/or tracheal aspirate throughout the time when the patients were in ...
Ruobing, Xiao, Shu, Yang, Fred, Koster, Chunyan, Ye, Chris, Stidley, Brian, Hjelle   +5 more
openaire   +2 more sources

Andes virus: from South American geographic isolation to international epidemiological concern

Práctica Familiar Rural
This section outlines the epidemiological evolution of the Andes orthohantavirus (ANDV), a New World hantavirus that has transitioned from a localized rural zoonosis in Argentina and Chile into a critical focus of international public health concern ...
Diego Herrera
doaj   +1 more source