Results 61 to 70 of about 2,392 (192)

Conserved Endonuclease Function of Hantavirus L Polymerase. [PDF]

, 2016
Hantaviruses are important emerging pathogens belonging to the Bunyaviridae family. Like other segmented negative strand RNA viruses, the RNA-dependent RNA polymerase (RdRp) also known as L protein of hantaviruses lacks an intrinsic "capping activity ...
Engler, O., Johansson, M.U., Kunz, S., Rothenberger, S., Torriani, G.   +4 more
core   +2 more sources

A Cluster of Three Cases of Hantavirus Pulmonary Syndrome among Canadian Military Personnel

Canadian Journal of Infectious Diseases and Medical Microbiology, Volume 2016, Issue 1, 2016., 2016
Hantavirus pulmonary syndrome (HPS) is a rare illness in eastern Canada. We present three cases of HPS among military personnel in Quebec. The three cases shared a common exposure to mouse excreta while engaged in military training in Alberta, a western province of Canada.
Leighanne O. Parkes, Trong Tien Nguyen, Jean Longtin, Marie-Claude Beaudoin, Julie Bestman-Smith, Donald C. Vinh, Guy Boivin, Vivian G. Loo, Marianna Ofner   +8 more
wiley   +1 more source

Research progress on hantavirus vaccines: a review

Zhongguo gonggong weisheng
Hantaviruses, belonging to the genus hantavirus within the family Bunyaviridae, are enveloped, segmented, negative-sense, single-stranded RNA viruses prevalent worldwide.
Jun LIU, Ruiting TANG, Jiayun DING, Yanju QIN, Yang LIU, Zhijian ZHOU   +5 more
doaj   +1 more source

Human hantavirus infections: epidemiology, clinical features, pathogenesis and immunology

Swiss Medical Weekly, 2014
In humans, hantaviruses can cause haemorrhagic fever with renal syndrome (HFRS) or hantavirus cardiopulmonary syndrome (HCPS). Currently it is estimated that 150,000 to 200,000 cases of hantavirus disease occur each year, the majority being reported
Tobias Manigold, Pablo Vial
doaj   +1 more source

Sin Nombre Viral RNA Load in Patients with Hantavirus Cardiopulmonary Syndrome [PDF]

The Journal of Infectious Diseases, 2006
To address the role that viral load plays in pathogenesis in patients with hantavirus cardiopulmonary syndrome (HCPS), we quantified Sin Nombre virus S segment viral RNA in plasma samples from 27 acutely ill patients. For 6 patients, we examined viral load in matched plasma, urine, and/or tracheal aspirate throughout the time when the patients were in ...
Ruobing, Xiao, Shu, Yang, Fred, Koster, Chunyan, Ye, Chris, Stidley, Brian, Hjelle   +5 more
openaire   +2 more sources

Delayed viral clearance despite high number of activated T cells during the acute phase in Argentinean patients with hantavirus pulmonary syndrome [PDF]

, 2022
Background: The hallmarks of HPS are increase of vascular permeability and endothelial dysfunction. Although an exacerbated immune response is thought to be implicated in pathogenesis, clear evidence is still elusive.
Alonso, Daniel Oscar, Bellomo, Carla María, Coelho, Rocío María, Di Paola, Nicholas, Dighero Kemp, Bonnie, García, Marina, Iglesias, Ayelén Aluminé, Kuhn, Jens H., Lewis, Lorena Cecilia, Martinez, Valeria Paula, Olivera, Camila Paula, Palacios, Gustavo, Periolo, Natalia, Rosario Anselmo, Constanza, Sanchez Lockhart, Mariano, Schierloh, Luis Pablo, Sharma, Heema   +16 more
core   +1 more source

Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems as Models

Ecology and Evolution, Volume 15, Issue 6, June 2025.
In this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Andreas Eleftheriou, Angela D. Luis
wiley   +1 more source

Epstein‐Barr Virus‐Related Hemophagocytic Lymphohistiocytosis: Hematologic Emergency in the Critical Care Setting

Case Reports in Hematology, Volume 2015, Issue 1, 2015., 2015
Hemophagocytic lymphohistiocytosis (HLH) is a rare and potential life‐threatening clinical syndrome that results from uncontrolled activation of the immune system. Secondary HLH, more commonly observed in adult patients, is seen in the context of underlying triggering conditions.
Neda Hashemi-Sadraei, Pimprapa Vejpongsa, Muhamed Baljevic, Lei Chen, Modupe Idowu, Chihaya Imai   +5 more
wiley   +1 more source

Orthohantavirus Survey in Indigenous Lands in a Savannah-Like Biome, Brazil

Viruses, 2021
In Brazil, the first confirmed cases of hantavirus cardiopulmonary syndrome in Indigenous populations occurred in 2001. The purpose of this study was to determine the seroprevalence of orthohantavirus infections in the Utiariti Indigenous land located in
Ana Cláudia Pereira Terças-Trettel, Alba Valéria Gomes de Melo, Renata Carvalho de Oliveira, Alexandro Guterres, Jorlan Fernandes, Liana Stretch Pereira, Marina Atanaka, Mariano Martinez Espinosa, Bernardo Rodrigues Teixeira, Cibele Rodrigues Bonvicino, Paulo Sérgio D’Andrea, Elba Regina Sampaio de Lemos   +11 more
doaj   +1 more source

Human and rodent humoral immune responses to Andes virus structural proteins [PDF]

, 2005
In the present work we identified B-cell epitopes recognized by sera of humans and rodents naturally infected with Andes virus, a hantavirus present in Chile and Argentina.
Tischler, Nicole D., Galeno, Héctor, Rosemblatt, Mario, Valenzuela, Pablo D.T.   +3 more
core   +1 more source