Results 51 to 60 of about 1,431 (145)

Laboratory Data Analysis of Hemorrhagic Fever With Renal Syndrome Patients to Predict Disease Severity and Patient Prognosis

Journal of Clinical Laboratory Analysis, Volume 39, Issue 23, December 2025.
Prompt access to care with proper treatment is essential for preventing patients from developing renal failure and unfavorable outcomes. This study aimed to elucidate laboratory parameters associated with HFRS severity and prognosis to predict disease course and initiate prompt clinical management.
Hong Shi, Feng Du, Ting Wang, Zhendong Gu, Ting Ruan, Qiujian Zhao, Rui Xu, Yi Wang, Langxi Luo, Shaohua Wang, Liejun Jiang, Yaoni Li   +11 more
wiley   +1 more source

Detection of Brazilian hantavirus by reverse transcription polymerase chain reaction amplification of N gene in patients with hantavirus cardiopulmonary syndrome

Memorias do Instituto Oswaldo Cruz, 2004
We report a nested reverse transcription-polymerase chain reaction (RT-PCR) assay for hantavirus using primers selected to match high homology regions of hantavirus genomes detected from the whole blood of hantavirus cardiopulmonary syndrome (HCPS ...
Marcos Lázaro Moreli, Ricardo Luiz Moro de Sousa, Luiz Tadeu Moraes Figueiredo   +2 more
doaj   +1 more source

Unraveling the Mechanistic Links Between Species Diversity and Infection Risk From Zoonotic Pathogens With Direct Transmission Among Reservoir Hosts: Rodent‐Orthohantavirus Systems as Models

Ecology and Evolution, Volume 15, Issue 6, June 2025.
In this review, we synthesize mechanistic evidence for diversity‐disease patterns in rodent‐orthohantavirus systems in the Americas, models of directly transmitted disease systems. We found that host regulation has been examined the most while other mechanisms have received less attention. Based on our findings, we propose that for a negative diversity‐
Andreas Eleftheriou, Angela D. Luis
wiley   +1 more source

Antibody levels to hantavirus in inhabitants of western Santa Catarina State, Brazil

Revista do Instituto de Medicina Tropical de São Paulo, 2012
Hantavirus cardiopulmonary syndrome (HCPS) is an infectious disease caused by hantaviruses of the family Bunyaviridae, and is transmitted by aerosols of excreta of infected rodents.
William Marciel de Souza, Alex Martins Machado, Geonildo Rodrigo Disner, Everton Boff, Aline Rafaela da Silva Rodrigues Machado, Michelly de Padua, Luiz Tadeu Moraes Figueiredo, Gustavo Borba de Miranda   +7 more
doaj   +1 more source

Hantaan virus glycoprotein Gc induces NEDD4‐dependent PTEN ubiquitination and degradation to escape the restriction of autophagosomes and facilitate viral propagation

The FASEB Journal, Volume 39, Issue 1, 15 January 2025.
The proposed model of HTNV induced PTEN degradation and PTEN‐regulated autophagy in progeny virus production: In HTNV‐infected HK‐2 cells, the viral Gc glycoprotein specifically promotes NEDD4 mediated ubiquitination and degradation of PTEN. Disruption of PTEN expression prevents autophagosome formation and increases HTNV production, whereas ...
Shuang Lu, Shuliang Chen, Yuqing Zhang, Xiaoli Mou, Mingyang Li, Shaowei Zhu, Xingyuan Chen, Tomas M. Strandin, Yale Jiang, Zhoufu Xiang, Yuanyuan Liu, Hairong Xiong, Deyin Guo, Liangjun Chen, Yirong Li, Wei Hou, Fan Luo   +16 more
wiley   +1 more source

Unveiling the impacts of land use on the phylogeography of zoonotic New World Hantaviruses

Ecography, Volume 2024, Issue 10, October 2024.
Billions of genomic sequences and records of species occurrence are available in public repositories (e.g. National Center for Biotechnology Information, NCBI and the Global Biodiversity Information Facility, GBIF). By implementing analytical tools from different scientific disciplines, data mining these databases can aid in the global surveillance of ...
Gabriel E. García‐Peña, André V. Rubio   +1 more
wiley   +1 more source

Andes virus: from South American geographic isolation to international epidemiological concern

Práctica Familiar Rural
This section outlines the epidemiological evolution of the Andes orthohantavirus (ANDV), a New World hantavirus that has transitioned from a localized rural zoonosis in Argentina and Chile into a critical focus of international public health concern ...
Diego Herrera
doaj   +1 more source

Sin Nombre Viral RNA Load in Patients with Hantavirus Cardiopulmonary Syndrome [PDF]

The Journal of Infectious Diseases, 2006
To address the role that viral load plays in pathogenesis in patients with hantavirus cardiopulmonary syndrome (HCPS), we quantified Sin Nombre virus S segment viral RNA in plasma samples from 27 acutely ill patients. For 6 patients, we examined viral load in matched plasma, urine, and/or tracheal aspirate throughout the time when the patients were in ...
Ruobing, Xiao, Shu, Yang, Fred, Koster, Chunyan, Ye, Chris, Stidley, Brian, Hjelle   +5 more
openaire   +2 more sources

A Severe Case of Hantavirus Cardiopulmonary Syndrome in a Patient Presenting as STEMI

Journal of Cardiovascular Emergencies, 2023
Hantavirus cardiopulmonary syndrome (HCPS) is a rare disease caused by Hantaviruses, that are transmitted from rodents to humans through aerosols. In some patients, HCPS can have a severe evolution, with rapid progression to respiratory distress and ...
Dobrica Diana, Udroiu Cristian Alexandru, Galrinho Ruxandra Drăgoi, Borjog Tudor, Vinereanu Dragos   +4 more
doaj   +1 more source

Orthohantavirus Survey in Indigenous Lands in a Savannah-Like Biome, Brazil

Viruses, 2021
In Brazil, the first confirmed cases of hantavirus cardiopulmonary syndrome in Indigenous populations occurred in 2001. The purpose of this study was to determine the seroprevalence of orthohantavirus infections in the Utiariti Indigenous land located in
Ana Cláudia Pereira Terças-Trettel, Alba Valéria Gomes de Melo, Renata Carvalho de Oliveira, Alexandro Guterres, Jorlan Fernandes, Liana Stretch Pereira, Marina Atanaka, Mariano Martinez Espinosa, Bernardo Rodrigues Teixeira, Cibele Rodrigues Bonvicino, Paulo Sérgio D’Andrea, Elba Regina Sampaio de Lemos   +11 more
doaj   +1 more source