Results 111 to 120 of about 19,179 (196)

Systematic prioritization of candidate genes in camptothecin biosynthesis using multi‐omics and deep learning

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Camptothecin (CPT), a plant‐derived monoterpene indole alkaloid first identified in Camptotheca acuminata, is a drug precursor widely used for cancer chemotherapeutics. However, the full set of genes responsible for CPT biosynthesis remains unclear, hindering efforts to elucidate the complete pathway or establish biosynthetic production of CPT
Shenqi Wang, Xing Wu, Maria Moreno, Joonseok Oh, Stephen L. Dellaporta, Jason M. Crawford, Farren J. Isaacs   +6 more
wiley   +1 more source

Advances in doubled haploid technology for rice breeding: mechanisms, applications, and future perspectives

Frontiers in Plant Science
Production of homozygous inbred lines is crucial in rice breeding programs. Doubled haploid (DH) technology enables the efficient development of pure lines and significantly shortens the breeding cycle compared to conventional methods.
Yiling Lin, Fangming Mao, Yuheng Huang, Derun Huang, Kejian Wang, Kejian Wang, Song Yan, Chaolei Liu   +7 more
doaj   +1 more source

A high‐quality haplotype‐resolved genome of Pyrus calleryana provides insights into adaptive gene families

The Plant Genome, Volume 19, Issue 3, September 2026.
Abstract Callery pear (Pyrus calleryana) is a deciduous species native to East Asia with notable ornamental and ecological value, but the genomic resources for this species remain limited. Here, we report the first haplotype‐resolved, chromosome‐scale genome of P. calleryana.
Xiaogang Dai, Xiaoyue Yang, Changci Jiang, Lizhen Huang, Fangping Li, Zhuangwei Hou, Fenghou Shi, Zefu Wang, Wenjie Yang, Yongbao Shen   +9 more
wiley   +1 more source

The 3D genome of Gigaspora margarita unveils stable chromatin and nucleolar organization and symbiont‐dependent genome dynamics

New Phytologist, Volume 251, Issue 5, Page 2799-2817, September 2026.
Summary Arbuscular mycorrhizal fungi (AMF) are widespread plant symbionts that enhance nutrient acquisition and influence ecosystem productivity. Previous chromosome‐level assemblies of the model species Rhizophagus irregularis revealed a two‐compartment genome architecture (active A and repressed B chromatin compartments), yet its conservation across ...
Ken Mugambi, Jordana Oliveira, Franco Magurno, Alessandra Salvioli di Fossalunga, Mara Novero, Luisa Lanfranco, Stefano Ghignone, Gökalp Yildirir, Yan Wang, Paola Bonfante, Nicolas Corradi   +10 more
wiley   +1 more source

Fish Sperm Subpopulations Detection, Separation, and Application: Current State and Trends

Reviews in Aquaculture, Volume 18, Issue 4, September 2026.
Modern advances in sperm biology highlight the necessity of recognising intra‐ejaculate heterogeneity as a central concept for advancing both the fundamental understanding of fertilisation processes and the development of artificial reproduction techniques in fishes. ABSTRACT Sperm subpopulations represent a fundamental manifestation of intra‐ejaculate
Viktoriya Dzyuba, William V. Holt, Borys Dzyuba   +2 more
wiley   +1 more source

Establishment and inheritance of minichromosomes from Arabidopsis haploid induction. [PDF]

Chromosoma, 2023
Tan EH, Ordoñez B, Thondehaalmath T, Seymour DK, Maloof JN, Maruthachalam R, Comai L.   +6 more
europepmc   +1 more source

An Update on Advancement in Genomics Resources for Spiny Lobster Aquaculture Development

Reviews in Aquaculture, Volume 18, Issue 4, September 2026.
ABSTRACT The rapid advancement of high‐throughput sequencing technologies has transformed aquaculture genomics, enabling unprecedented insights into the biology and improvement of non‐model aquatic species. Among crustaceans, lobsters represent one of the most commercially valuable yet genomically underexplored taxa. This review synthesises the current
Courtney Lewis, Ahmad Farhadi, Susan Glendinning, Thomas Banks, Tara Kelly, Andrew G. Jeffs, Sandra Infante Villamil, John Breen, Jennifer M. Cobcroft, Arya Vazirzadeh, Basseer M. Codabaccus, Chris G. Carter, Quinn P. Fitzgibbon, Gregory G. Smith, Tomer Ventura   +14 more
wiley   +1 more source

High-throughput haploid induction in species with bisexual flowers. [PDF]

Plant Commun, 2023
Qi X, Liu J, Liu Z, Chen C, Chen B, Guo S, Ni Z, Zhong Y, Chen S, Liu C.   +9 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, Volume 20, Issue 8, Page 1913-1932, August 2026.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

The power of many: when genetics met yeasts and high‐throughput

Biological Reviews, Volume 101, Issue 4, Page 1662-1682, August 2026.
ABSTRACT In recent years, complex technological capabilities have evolved, driven by the need to solve complex and integrative biological questions through global analyses. New equipment allows the scaling up and automation of processes which previously were carried out on a very limited scale.
Víctor A. Tallada, Víctor Carranco
wiley   +1 more source