Results 1 to 10 of about 407,509 (363)

Mapping Haplotype-haplotype Interactions with Adaptive LASSO [PDF]

BMC Genetics, 2010
Background The genetic etiology of complex diseases in human has been commonly viewed as a complex process involving both genetic and environmental factors functioning in a complicated manner.
Li Ming, Romero Roberto, Fu Wenjiang J, Cui Yuehua   +3 more
doaj   +3 more sources

popart: full‐feature software for haplotype network construction [PDF]

, 2015
Jessica Leigh, David Bryant
openalex   +2 more sources

First genetic insights of Gonatodes caudiscutatus (Reptilia, Gekkota) in the Galapagos Islands and mainland Ecuador [PDF]

Biodiversity Data Journal, 2023
Studies on genetic variability amongst native and introduced species contribute to a better understanding of the genetic diversity of species along their autochthonous distribution and identify possible routes of introduction.
Lía Altamirano-Ponce, Mateo Dávila-Játiva, Gabriela Pozo, María José Pozo, Martín Terán-Velástegui, Carlos Daniel Cadena, Diego Cisneros-Heredia, Maria de Lourdes Torres   +7 more
doaj   +3 more sources

A common variant associated with dyslexia reduces expression of the KIAA0319 gene [PDF]

, 2013
This work was supported by the Wellcome Trust (MYD, SP, TSS, JCK, RWM, PC, SB, and APM), the Intramural Research Programs of the National Human Genome Research Institute (MYD and EDG) and National Cancer Institute (MPO), and the NIH/Ox-Cam Graduate ...
Beck, Stephan, Coggill, Penny, Dennis, Megan Y., Green, Eric D., Knight, Julian C., Monaco, Anthony P., Paracchini, Silvia, Prokunina-Olsson, Ludmila, Scerri, Thomas S., Wade-Martins, Richard   +9 more
core   +11 more sources

Genetic and Haplotype Diversity of Manila Clam Ruditapes philippinarum in Different Regions of China Based on Three Molecular Markers

Animals, 2023
China has the largest production yield of Manila clam Ruditapes philippinarum in the world. Most of the clam seeds for aquaculture are mainly derived from artificial breeding in southern China, likely resulting in the loss of genetic variation and ...
Di Wei, Sichen Zheng, Songlin Wang, Jingkai Yan, Zhihong Liu, Liqing Zhou, Biao Wu, Xiujun Sun   +7 more
doaj   +1 more source

Outcome differences in HPV-driven head and neck squamous cell carcinoma attributable to altered human leukocyte antigen frequencies

Frontiers in Oncology, 2023
BackgroundEffective immune surveillance requires a functioning immune system and natural killer (NK) and T cells for adequate innate and antigen-specific immune responses critically depending on human leukocyte antigens (HLAs) and haplotypes representing
Gunnar Wichmann, Nathalie Vetter, Claudia Lehmann, Ramona Landgraf, Ilias Doxiadis, Rebecca Großmann, Ekaterina Vorobeva, Andreas Dietz, Veit Zebralla, Susanne Wiegand, Theresa Wald   +10 more
doaj   +1 more source

Positive Selection and Adaptive Introgression of Haplotypes from Bos indicus Improve the Modern Bos taurus Cattle

Agriculture, 2022
Complex evolutionary processes, such as positive selection and introgression can be characterized by in-depth assessment of sequence variation on a whole-genome scale.
Qianqian Zhang, Anna Amanda Schönherz, Mogens Sandø Lund, Bernt Guldbrandtsen   +3 more
doaj   +1 more source

The haplotype-resolved chromosome pairs of a heterozygous diploid African cassava cultivar reveal novel pan-genome and allele-specific transcriptome features

GigaScience, 2022
Background Cassava (Manihot esculenta) is an important clonally propagated food crop in tropical and subtropical regions worldwide. Genetic gain by molecular breeding has been limited, partially because cassava is a highly heterozygous crop with a ...
Chao Fang, Huanzi Zhong, Yuxiang Lin, Bing Chen, Mo Han, Huahui Ren, Haorong Lu, Jacob M. Luber, Min Xia, Wangsheng Li, Shayna Stein, Xun Xu, Wenwei Zhang, R. Drmanac, J. Wang, H. Yang, Lennart Hammarström, A. D. Kostic, Karsten Kristiansen, Junhua Li   +19 more
semanticscholar   +1 more source

Haplotype-resolved diverse human genomes and integrated analysis of structural variation

Science, 2021
Resolving genomic structural variation Many human genomes have been reported using short-read technology, but it is difficult to resolve structural variants (SVs) using these data.
Peter Ebert, P. Audano, Qihui Zhu, Bernardo Rodriguez-Martin, David Porubsky, M. Bonder, Arvis Sulovari, Jana Ebler, Weichen Zhou, Rebecca Serra Mari, F. Yilmaz, Xuefang Zhao, Pinghsun Hsieh, Joyce Lee, Sushant Kumar, Jiadong Lin, T. Rausch, Yu Chen, Jingwen Ren, Martín Santamarina, Wolfram Höps, Hufsah Ashraf, Nelson Chuang, Xiaofei Yang, Katherine M. Munson, Alexandra P. Lewis, S. Fairley, L. Tallon, Wayne E. Clarke, A. Basile, M. Byrska-Bishop, A. Corvelo, U. S. Evani, Tsung-Yu Lu, Mark J. P. Chaisson, Junjie Chen, Chong Li, H. Brand, A. Wenger, M. Ghareghani, William T. Harvey, Benjamin Raeder, Patrick Hasenfeld, Allison A. Regier, H. Abel, Ira M. Hall, Paul Flicek, O. Stegle, M. Gerstein, J. Tubío, Zepeng Mu, Yang I. Li, Xinghua Shi, A. Hastie, K. Ye, Zechen Chong, A. Sanders, M. Zody, M. Talkowski, Ryan E. Mills, S. Devine, Charles Lee, J. Korbel, T. Marschall, E. Eichler   +64 more
semanticscholar   +1 more source

Detecting Local Haplotype Sharing and Haplotype Association [PDF]

Genetics, 2014
Abstract A novel haplotype association method is presented, and its power is demonstrated. Relying on a statistical model for linkage disequilibrium (LD), the method first infers ancestral haplotypes and their loadings at each marker for each individual.
Xu, Hanli, Guan, Yongtao
openaire   +2 more sources