Results 1 to 10 of about 290,368 (328)

Mapping Haplotype-haplotype Interactions with Adaptive LASSO [PDF]

open access: yesBMC Genetics, 2010
Background The genetic etiology of complex diseases in human has been commonly viewed as a complex process involving both genetic and environmental factors functioning in a complicated manner.
Li Ming   +3 more
doaj   +4 more sources

Genotyping of invasive Ponto-Caspian gobies in Croatia [PDF]

open access: yesJournal of Central European Agriculture, 2020
The biology and ecology of non-native freshwater Ponto-Caspian (P-C) gobies: monkey goby, Neogobius fluviatilis (Pallas, 1814), round goby, Neogobius melanostomus (Pallas, 1814) and bighead goby, Ponticola kessleri (Günther, 1861) have been studied in ...
Goran Jakšić   +6 more
doaj   +1 more source

Extinction and emergence of genomic haplotypes during the evolution of Avian coronavirus in chicken embryos [PDF]

open access: yesGenetics and Molecular Biology, 2020
Avian coronavirus (AvCoV) is ubiquitously present on poultry as a multitude of virus lineages. Studies on AvCoV phenotypic traits are dependent on the isolation of field strains in chicken embryonated eggs, but the mutant spectrum on each isolate is not ...
Paulo E. Brandão   +4 more
doaj   +1 more source

A Detailed View of KIR Haplotype Structures and Gene Families as Provided by a New Motif-Based Multiple Sequence Alignment

open access: yesFrontiers in Immunology, 2020
Human chromosome 19q13.4 contains genes encoding killer-cell immunoglobulin-like receptors (KIR). Reported haplotype lengths range from 67 to 269 kb and contain 4 to 18 genes.
David Roe   +7 more
doaj   +1 more source

Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country

open access: yesFrontiers in Microbiology, 2020
Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the ...
Lishuang Shen   +8 more
doaj   +1 more source

The Path to Conserved Extended Haplotypes: Megabase-Length Haplotypes at High Population Frequency

open access: yesFrontiers in Genetics, 2021
This minireview describes the history of the conceptual development of conserved extended haplotypes (CEHs): megabase-length haplotypes that exist at high (≥0.5%) population frequency.
Chester A. Alper, Chester A. Alper
doaj   +1 more source

Exploring effective approaches for haplotype block phasing

open access: yesBMC Bioinformatics, 2019
Background Knowledge of phase, the specific allele sequence on each copy of homologous chromosomes, is increasingly recognized as critical for detecting certain classes of disease-associated mutations. One approach for detecting such mutations is through
Ziad Al Bkhetan   +4 more
doaj   +1 more source

Introgression Breeding in Barley: Perspectives and Case Studies

open access: yesFrontiers in Plant Science, 2020
Changing production scenarios resulting from unstable climatic conditions are challenging crop improvement efforts. A deeper and more practical understanding of plant genetic resources is necessary if these assets are to be used effectively in developing
Javier Hernandez   +2 more
doaj   +1 more source

A simple PCR-RFLP method for genetic phase determination in compound heterozygotes

open access: yesFrontiers in Genetics, 2012
When susceptibility to diseases is caused by cis-effects of multiple alleles at adjacent polymorphic sites, it may be difficult to assess with confidence the genetic phase and identify individuals carrying the risk haplotype.
Rodney T Perry   +2 more
doaj   +1 more source

GIPR rs10423928 and bone mineral density in postmenopausal women in Shanghai

open access: yesEndocrine Connections, 2022
We demonstrated previously that there is a correlation between glucagon-like peptide-1 (GLP-1) single-nucleotide polymorphism (SNP) and bone mineral density in postmenopausal women.
Lizhi Zhang   +5 more
doaj   +1 more source

Home - About - Disclaimer - Privacy