Results 1 to 10 of about 295,678 (328)

Mapping Haplotype-haplotype Interactions with Adaptive LASSO [PDF]

BMC Genetics, 2010
Background The genetic etiology of complex diseases in human has been commonly viewed as a complex process involving both genetic and environmental factors functioning in a complicated manner.
Li Ming, Romero Roberto, Fu Wenjiang J, Cui Yuehua   +3 more
doaj   +4 more sources

First genetic insights of Gonatodes caudiscutatus (Reptilia, Gekkota) in the Galapagos Islands and mainland Ecuador [PDF]

Biodiversity Data Journal, 2023
Studies on genetic variability amongst native and introduced species contribute to a better understanding of the genetic diversity of species along their autochthonous distribution and identify possible routes of introduction.
Lía Altamirano-Ponce, Mateo Dávila-Játiva, Gabriela Pozo, María José Pozo, Martín Terán-Velástegui, Carlos Daniel Cadena, Diego Cisneros-Heredia, Maria de Lourdes Torres   +7 more
doaj   +3 more sources

A Common Variant Associated with Dyslexia Reduces Expression of the KIAA0319 Gene [PDF]

, 2009
Numerous genetic association studies have implicated the KIAA0319 gene on human chromosome 6p22 in dyslexia susceptibility. The causative variant(s) remains unknown but may modulate gene expression, given that (1) a dyslexia-associated haplotype has been
Megan Y. Dennis, Silvia Paracchini, Thomas S. Scerri, Ludmila Prokunina-Olsson, Julian C. Knight, Richard Wade-Martins, Penny Coggill, Stephan Beck, Eric D. Green, Anthony P. Monaco, Lisa Stubbs, SE Fisher, SE Shaywitz, SE Shaywitz, JC DeFries, JC DeFries, JM Finucci, JW Gilger, JC DeFries, M Taipale, TS Scerri, KG Wigg, K Hannula-Jouppi, H Meng, J Schumacher, C Francks, N Cope, D Harold, M Luciano, S Paracchini, H Anthoni, AM Galaburda, GD Rosen, SW Threlkeld, Y Wang, TJ Burbridge, S Paracchini, AM Galaburda, AJ Marlow, SE Fisher, GR Abecasis, JC Barrett, S Schwartz, NG Copeland, S Warming, GH Perdew, DC King, J Taylor, JW Thomas, A Visel, WJ Kent, AE Kel, R Kageyama, PI Lin, S Paracchini, JA Fiez, P Swoboda, R Dubruille, M Gotz, KY Chau, JD Klemm, RA Sturm, T Kiyota, MK Kim, J Bode, E Birney, JC Knight, T Pastinen   +67 more
core   +10 more sources

Genetic and Haplotype Diversity of Manila Clam Ruditapes philippinarum in Different Regions of China Based on Three Molecular Markers

Animals, 2023
China has the largest production yield of Manila clam Ruditapes philippinarum in the world. Most of the clam seeds for aquaculture are mainly derived from artificial breeding in southern China, likely resulting in the loss of genetic variation and ...
Di Wei, Sichen Zheng, Songlin Wang, Jingkai Yan, Zhihong Liu, Liqing Zhou, Biao Wu, Xiujun Sun   +7 more
doaj   +1 more source

Outcome differences in HPV-driven head and neck squamous cell carcinoma attributable to altered human leukocyte antigen frequencies

Frontiers in Oncology, 2023
BackgroundEffective immune surveillance requires a functioning immune system and natural killer (NK) and T cells for adequate innate and antigen-specific immune responses critically depending on human leukocyte antigens (HLAs) and haplotypes representing
Gunnar Wichmann, Nathalie Vetter, Claudia Lehmann, Ramona Landgraf, Ilias Doxiadis, Rebecca Großmann, Ekaterina Vorobeva, Andreas Dietz, Veit Zebralla, Susanne Wiegand, Theresa Wald   +10 more
doaj   +1 more source

The role of neuromedin U in adiposity regulation. Haplotype analysis in European children from the IDEFICS Cohort [PDF]

, 2017
Background and aims: Neuromedin U (NMU) is a hypothalamic neuropeptide with important roles in several metabolic processes, recently suggested as potential therapeutic target for obesity.
Gianfagna, Francesco, Grippi, Claudio, Ahrens, Wolfgang, Bailey, Mark E.S., Börnhorst, Claudia, De Henauw, Stefan, Foraita, Ronja, Koni, Anna C., Krogh, Vittorio, Mårild, Staffan, Molnár, Dénes, Moreno, Luis, Pitsiladis, Yannis, Russo, Paola, Siani, Alfonso, Tornaritis, Michael, Veidebaum, Toomas, Iacoviello, Licia   +17 more
core   +18 more sources

Positive Selection and Adaptive Introgression of Haplotypes from Bos indicus Improve the Modern Bos taurus Cattle

Agriculture, 2022
Complex evolutionary processes, such as positive selection and introgression can be characterized by in-depth assessment of sequence variation on a whole-genome scale.
Qianqian Zhang, Anna Amanda Schönherz, Mogens Sandø Lund, Bernt Guldbrandtsen   +3 more
doaj   +1 more source

Viral population estimation using pyrosequencing [PDF]

, 2008
The diversity of virus populations within single infected hosts presents a major difficulty for the natural immune response as well as for vaccine design and antiviral drug therapy.
A Dempster, A Rambaut, AMN Tsibris, B Gaschen, Baback Gharizadeh, C Wang, Chunlin Wang, D O'Meara, DC Douek, E Domingo, E Halperin, EH Simpson, ES Lander, Glenn Tesler, GS Gottlieb, GW Tyson, H Fakhrai-Rad, I Malet, IM Rouzine, J Kececioglu, JE Hopcroft, JF Simons, K Chen, KJ Metzner, L Bacheler, L Doukhan, L Excoffier, Lior Pachter, LR Ford, M Breitbart, M Eigen, M Margulies, M Stephens, MA Nowak, MJ Gonzales, ML Collins, ML Sogin, Mostafa Ronaghi, MT Tammi, N Beerenwinkel, Nicholas Eriksson, Niko Beerenwinkel, P Jenkins, PA Pevzner, R Schmid, R Shankarappa, Robert W. Shafer, RP Dilworth, S Huse, S-Y Rhee, S-Y Rhee, Soo-Yon Rhee, VA Johnson, Yumi Mitsuya   +53 more
core   +10 more sources

Vast Gene Flow among the Spanish Populations of the Pest Bactrocera oleae (Diptera, Tephritidae), Phylogeography of a Metapopulation to Be Controlled and Its Mediterranean Genetic Context

Insects, 2022
Spain is the leading producer of olives and olive oil. Ninety-five percent of world production originate from Spain and other regions of the Mediterranean Basin.
Esther Lantero, Beatriz Matallanas, M. Dolores Ochando, Carmen Callejas   +3 more
doaj   +1 more source

Insights into the Mitochondrial and Nuclear Genome Diversity of Two High Yielding Strains of Laying Hens

Animals, 2021
Mitochondria are essential components of eukaryotes as they are involved in several organismic key processes such as energy production, apoptosis and cell growth. Despite their importance for the metabolism and physiology of all eukaryotic organisms, the
Clara Heumann-Kiesler, Vera Sommerfeld, Hanna Iffland, Jörn Bennewitz, Markus Rodehutscord, Martin Hasselmann   +5 more
doaj   +1 more source