Results 31 to 40 of about 303,688 (221)

Boosting Haplotype Inference with Local Search

, 2008
. A very challenging problem in the genetics domain is to infer haplotypes from genotypes. This process is expected to identify genes affecting health, disease and response to drugs.
Lynce, Ines, Marques-Silva, Joao, Prestwich, Steve   +2 more
core   +2 more sources

Minimum error correction-based haplotype assembly: considerations for long read data

, 2020
The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome.
de Ridder, Dick, Kahaei, Mohammad Hossein, Majidian, Sina   +2 more
core   +1 more source

Genetic diversity of Xanthomonas citri subsp. citri in citrus orchards in northwest Paraná state, Brazil

Phytopathologia Mediterranea, 2017
Xanthomonas citri subsp. citri, which causes Asiatic citrus canker (ACC), is an important pathogen of citrus in Brazil and elsewhere. The genetic diversity of X. citri subsp.
Aline GONÇALVES-ZULIANI, Carlos ZANUTTO, Juliana FRANCO, Andressa CAZETTA, Clive BOCK, William NUNES   +5 more
doaj   +1 more source

Comprehensive Genome Analysis of 6,000 USA SARS-CoV-2 Isolates Reveals Haplotype Signatures and Localized Transmission Patterns by State and by Country

Frontiers in Microbiology, 2020
Genomic analysis of SARS-CoV-2 sequences is crucial in determining the effectiveness of prudent safer at home measures in the United States (US). By haplotype analysis of 6,356 US isolates, we identified a pattern of strongly localized outbreaks at the ...
Lishuang Shen, Jennifer Dien Bard, Jennifer Dien Bard, Jaclyn A. Biegel, Jaclyn A. Biegel, Alexander R. Judkins, Alexander R. Judkins, Xiaowu Gai, Xiaowu Gai   +8 more
doaj   +1 more source

GIPR rs10423928 and bone mineral density in postmenopausal women in Shanghai

Endocrine Connections, 2022
We demonstrated previously that there is a correlation between glucagon-like peptide-1 (GLP-1) single-nucleotide polymorphism (SNP) and bone mineral density in postmenopausal women.
Lizhi Zhang, Jinwei He, Xiang Sun, Dongyue Pang, Jingjing Hu, Bo Feng   +5 more
doaj   +1 more source

Strong signature of natural selection within an FHIT intron implicated in prostate cancer risk [PDF]

, 2008
Previously, a candidate gene linkage approach on brother pairs affected with prostate cancer identified a locus of prostate cancer susceptibility at D3S1234 within the fragile histidine triad gene (FHIT), a tumor suppressor that induces apoptosis ...
A Auton, A Esquela-Kerscher, A Fischer, A Latil, A Vecchione, Al B. Benson, AM Adams, AM Levin, Cathryn Lundberg, CC Spencer, Ching Ouyang, D Charlesworth, D Gordon, DA Nickerson, David Johnson, DJ Schaid, E Dudbridge, EM Reis, ET Dermitzakis, F Tajima, FM De La Vega, G Sozzi, G Thomas, Garrett Larson, GP Larson, Guillermo Rivas, HH Nelson, J Gudmundsson, J Gudmundsson, J Gudmundsson, James A. Stewart, JC Barrett, JC Fay, Jeffrey Weitzel, Jerry Slater, JM Bland, John Archambeau, John M. Kirkwood, JS Pedersen, JS Rhim, K Huebner, K Preacher, Louis Geller, M Bamshad, M Nei, M Stephens, M Stephens, M Yeager, Magnus Nordborg, Mary B. Daly, Matthew W. Hahn, N Yu, NA Becker, P Kapranov, Peter J. O'Dwyer, PI Lin, RA Eeles, Rebecca Sutphen, RL Fouts, RR Hudson, S Wooding, SB Gabriel, T Bersaglieri, Theodore G. Krontiris, V Chizhikov, Yan Ding, YX Fu, Z Guo   +67 more
core   +4 more sources

Molecular characterization of the noble crayfish (Astacus astacus L.) population from Pomeranian lakes (north-western Poland) based on mitochondrial DNA

Knowledge and Management of Aquatic Ecosystems, 2016
The genetic variability between individuals from five crayfish (Astacus astacus L.) populations was determined. The analysis was based on sequences variations of mitochondrial DNA (cytochrome oxidase subunit I (COI) and 16S ribosomal
Skuza L., Keszka S., Panicz R., Śmietana P.   +3 more
doaj   +1 more source

A case-control study of rheumatoid arthritis identifies an associated single nucleotide polymorphism in the NCF4 gene, supporting a role for the NADPH-oxidase complex in autoimmunity [PDF]

, 2007
Rheumatoid arthritis (RA) is a chronic inflammatory disease with a heritability of 60%. Genetic contributions to RA are made by multiple genes, but only a few gene associations have yet been confirmed.
Alfredsson, L, Burkhardt, H, Holmdahl, Rikard,, Kallberg, H, Klareskog, L, Lindqvist, Anna-Karin,, Lund University., Olsson, Lina,, Padyukov, L   +8 more
core   +2 more sources

BjuB05.GS1.4 promotes nitrogen assimilation and participates in the domestication of shoot nitrogen use efficiency in Brassica juncea

Journal of Integrative Agriculture
Elucidating crops’ physiological and molecular mechanisms to adapt to low nitrogen environment and promoting nitrogen transfer from senescent leaves to new leaves is crucial in improving Brassica’s nitrogen use efficiency (NUE). Glutamine synthetase gene
Rumeng Wang, Jinsong Luo, Jian Zeng, Yingying Xiong, Tianchu Shu, Dawei He, Zhongsong Liu, Zhenhua Zhang   +7 more
doaj   +1 more source

The association of 20 short tandem repeat loci of autosomal chromosome with male schizophrenia

Brain and Behavior, 2022
Introduction Schizophrenia's heritability and familial transmission have been known for several decades. The male‐specific Y chromosome plays an important role in schizophrenia.
Chun Yang, Huajie Ba, Huihui Zou, Xianju Zhou   +3 more
doaj   +1 more source