Results 31 to 40 of about 290,368 (328)

Allelic variations of the multidrug resistance gene determine susceptibility and disease behavior in ulcerative colitis [PDF]

open access: yes, 2005
BACKGROUND AND AIMS: The MDR1 gene encodes P-glycoprotein 170, an efflux transporter that is highly expressed in intestinal epithelial cells. The MDR1 exonic single nucleotide polymorphisms (SNPs) C3435T and G2677T have been shown to correlate with ...
Arnott, Ian D   +7 more
core   +1 more source

A genome-wide combinatorial strategy dissects complex genetic architecture of seed coat colour in chickpea

open access: yesFrontiers in Plant Science, 2015
The study identified 9045 high-quality SNPs employing both genome-wide GBS- and candidate gene-based SNP genotyping assays in 172, including 93 cultivated (desi and kabuli) and 79 wild chickpea accessions.
Deepak eBajaj   +12 more
doaj   +1 more source

Of Genes, Blocks, and Haplotypes [PDF]

open access: yesBiology of Blood and Marrow Transplantation, 2012
indicate normal function. Today, functional assays such as with tetramer staining, intracellular cytokine staining, and degranulation assays, are becoming more readily available and allow us to functionally interrogate lymphocyte subpopulations. These assessments, if validated as predictors of infection and relapse, will not only help elucidate the ...
openaire   +3 more sources

Minimum error correction-based haplotype assembly: considerations for long read data

open access: yes, 2020
The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome.
de Ridder, Dick   +2 more
core   +1 more source

Linkage between increased nociception and olfaction via a SCN9A haplotype [PDF]

open access: yes, 2013
Background and Aims: Mutations reducing the function of Nav1.7 sodium channels entail diminished pain perception and olfactory acuity, suggesting a link between nociception and olfaction at ion channel level.
Doehring, Alexandra   +4 more
core   +2 more sources

The emergence of resistance to the benzimidazole anthlemintics in parasitic nematodes of livestock is characterised by multiple independent hard and soft selective sweeps [PDF]

open access: yes, 2015
Anthelmintic resistance is a major problem for the control of parasitic nematodes of livestock and of growing concern for human parasite control. However, there is little understanding of how resistance arises and spreads or of the “genetic signature” of
Bartley, Yvonne   +7 more
core   +7 more sources

Molecular characterization of the noble crayfish (Astacus astacus L.) population from Pomeranian lakes (north-western Poland) based on mitochondrial DNA

open access: yesKnowledge and Management of Aquatic Ecosystems, 2016
The genetic variability between individuals from five crayfish (Astacus astacus L.) populations was determined. The analysis was based on sequences variations of mitochondrial DNA (cytochrome oxidase subunit I (COI) and 16S ribosomal
Skuza L.   +3 more
doaj   +1 more source

Genetic diversity of Xanthomonas citri subsp. citri in citrus orchards in northwest Paraná state, Brazil

open access: yesPhytopathologia Mediterranea, 2017
Xanthomonas citri subsp. citri, which causes Asiatic citrus canker (ACC), is an important pathogen of citrus in Brazil and elsewhere. The genetic diversity of X. citri subsp.
Aline GONÇALVES-ZULIANI   +5 more
doaj   +1 more source

Pure Parsimony Xor Haplotyping [PDF]

open access: yesIEEE/ACM Transactions on Computational Biology and Bioinformatics, 2009
The haplotype resolution from xor-genotype data has been recently formulated as a new model for genetic studies. The xor-genotype data is a cheaply obtainable type of data distinguishing heterozygous from homozygous sites without identifying the homozygous alleles.
BONIZZONI, PAOLA   +4 more
openaire   +10 more sources

Validation of genes affecting rice mesocotyl length through candidate association analysis and identification of the superior haplotypes

open access: yesFrontiers in Plant Science, 2023
Mesocotyl is an essential organ of rice for pushing buds out of soil and plays a crucial role in seeding emergence and development in direct-seeding. Thus, identify the loci associated with mesocotyl length (ML) could accelerate breeding progresses for ...
Yamei Wang   +9 more
doaj   +1 more source

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