Results 31 to 40 of about 407,509 (363)

Disease progression in Plasmodium knowlesi malaria is linked to variation in invasion gene family members. [PDF]

, 2014
Emerging pathogens undermine initiatives to control the global health impact of infectious diseases. Zoonotic malaria is no exception. Plasmodium knowlesi, a malaria parasite of Southeast Asian macaques, has entered the human population. P.
A Berry, AA Semenya, AK Bei, Angela Siner, Atique M. Ahmed, B Singh, B Singh, Balbir Singh, BE Barber, BE Barber, C Aurrecoechea, C Daneshvar, Chan Woon Lu, CV Jennings, EV Meyer, G Butcher, G Snounou, H Ozwara, Ing Tien Wong, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Cox-Singh, J Langhorne, J Li, J Rayner, Janet Cox-Singh, JC Barrett, JC Rayner, JC Rayner, JP Cramer, JW Barnwell, K Gunalan, K Hayton, Kenji Hirayama, KS Lee, L Excoffier, LH Bannister, LH Miller, LH Miller, M Willmann, MAM Sallum, Matthias Willmann, Miguel M. Pinheiro, MR Galinski, MR Galinski, N Gomez-Escobar, P Librado, Paul C. Divis, Ramlah Zainudin, RW Moon, S Kumar, S Lopaticki, S Nakazawa, Sanjeev Krishna, Sarina K. Singh-Khaira, Scott B. Millar, Sean Lynch, SL Takala, T William, TM DeSimone, WH Tham   +61 more
core   +3 more sources

Reference-based phasing using the Haplotype Reference Consortium panel

Nature Genetics, 2016
Haplotype phasing is a fundamental problem in medical and population genetics. Phasing is generally performed via statistical phasing in a genotyped cohort, an approach that can yield high accuracy in very large cohorts but attains lower accuracy in ...
Po-Ru Loh, P. Danecek, P. Palamara, C. Fuchsberger, Yakir A Reshef, Hilary K Finucane, S. Schoenherr, L. Forer, Shane A. McCarthy, G. Abecasis, R. Durbin, Alkes L Price   +11 more
semanticscholar   +1 more source

Non-coding and intergenic genetic variants of human arylamine N-acetyltransferase 2 (NAT2) gene are associated with differential plasma lipid and cholesterol levels and cardiometabolic disorders

Frontiers in Pharmacology, 2023
Arylamine N-acetyltransferase 2 (NAT2) is a phase II metabolic enzyme, best known for metabolism of aromatic amines and hydrazines. Genetic variants occurring in the NAT2 coding region have been well-defined and are known to affect the enzyme activity or
Kyung U. Hong, Kennedy M. Walls, David W. Hein   +2 more
doaj   +1 more source

FABP-2 and PPAR-γ Haplotype as Risk Factors for Dyslipidemia in a Type 2 Diabetes Mellitus Population of Santa Rosa del Conlara, San Luis, Argentina [PDF]

, 2014
Introduction: Type 2 Diabetes Mellitus (T2DM) is a complex disorder caused by the interaction between genetic predisposition and environmental factors. Genetics plays an important role on lipid homeostasis. Many genes are involved in the lipid metabolism,
Fernandez, Gustavo, Gonzalez, Irma Ines, Ojeda, Marta Susana, Olmos Nicotra, Maria Florencia, Siewert, Susana Elfrida   +4 more
core   +1 more source

Accurate, scalable and integrative haplotype estimation

Nature Communications, 2019
The number of human genomes being genotyped or sequenced increases exponentially and efficient haplotype estimation methods able to handle this amount of data are now required.
O. Delaneau, J. Zagury, M. Robinson, J. Marchini, E. Dermitzakis   +4 more
semanticscholar   +1 more source

Mitochondrial DNA signature for range-wide populations of Bicyclus anynana suggests a rapid expansion from recent refugia [PDF]

, 2011
This study investigates the genetic diversity, population structure and demographic history of the afrotropical butterfly Bicyclus anynana using mitochondrial DNA (mtDNA).
Brakefield, P.M., Eijk, M., van, Jong, M.A., de, Wahlberg, N., Zwaan, B.J.   +4 more
core   +1 more source

Haplotype-resolved genome analyses of a heterozygous diploid potato

Nature Genetics, 2020
Potato (Solanum tuberosum L.) is the most important tuber crop worldwide. Efforts are underway to transform the crop from a clonally propagated tetraploid into a seed-propagated, inbred-line-based hybrid, but this process requires a better understanding ...
Qian Zhou, Dié Tang, Wu Huang, Zhongmin Yang, Yu Zhang, J. Hamilton, R. Visser, C. Bachem, C. Robin Buell, Zhonghua Zhang, Chunzhi Zhang, Sanwen Huang   +11 more
semanticscholar   +1 more source

Analysis of the mtDNA D-loop Region Casts New Light on Philippine Red Junglefowl Phylogeny and Relationships to Other Junglefowl Species in Asia

The Journal of Poultry Science, 2022
Red junglefowl (RJF) is considered the ancestor of domestic chickens. However, the possible maternal origin, genetic diversity, and subspecies classification of the Philippine (PH) RJF remains uncertain.
Jade Dhapnee Z. Compendio, Jam Marrie Nanche P. Mantana, Masahide Nishibori   +2 more
doaj   +1 more source

Haplotype analysis of genomic prediction by incorporating genomic pathway information based on high-density SNP marker in Chinese yellow-feathered chicken

Poultry Science, 2023
: Genomic selection using single nucleotide polymorphism (SNP) markers is now intensively investigated in breeding and has been widely utilized for genetic improvement.
Haoqiang Ye, Zhenqiang Xu, Semiu Folaniyi Bello, Qianghui Zhu, Shaofen Kong, Ming Zheng, Xiang Fang, Xinzheng Jia, Haiping Xu, Xiquan Zhang, Qinghua Nie   +10 more
doaj   +1 more source

Multi-platform discovery of haplotype-resolved structural variation in human genomes

Nature Communications, 2017
The incomplete identification of structural variants (SVs) from whole-genome sequencing data limits studies of human genetic diversity and disease association.
Mark J. P. Chaisson, A. Sanders, Xuefang Zhao, A. Malhotra, David Porubsky, T. Rausch, E. Gardner, O. Rodriguez, Li Guo, Ryan L. Collins, Xian Fan, Jia Wen, R. Handsaker, S. Fairley, Zev N. Kronenberg, Xiangmeng Kong, F. Hormozdiari, Dillon Lee, A. Wenger, A. Hastie, Danny Antaki, P. Audano, H. Brand, Stuart Cantsilieris, H. Cao, Eliza Cerveira, Chong-Jian Chen, Xintong Chen, C. Chin, Zechen Chong, Nelson Chuang, D. Church, Laura Clarke, Andrew Farrell, Joey Flores, Timur Galeev, David U. Gorkin, Madhusudan Gujral, V. Guryev, W. H. Heaton, J. Korlach, Sushant Kumar, J. Kwon, Jong Eun Lee, Joyce Lee, Wan-Ping Lee, Sau Peng Lee, Patrick J. Marks, K. Viaud-Martinez, Sascha Meiers, Katherine M. Munson, Fábio C. P. Navarro, Bradley J. Nelson, Conor Nodzak, Amina Noor, S. Kyriazopoulou-Panagiotopoulou, A. Pang, Yunjiang Qiu, Gabriel Rosanio, Mallory Ryan, A. Stütz, D. Spierings, Alistair N. Ward, AnneMarie E Welch, M. Xiao, W. Xu, Chengsheng Zhang, Qihui Zhu, Xiangqun Zheng-Bradley, G. Jun, L. Ding, C. Koh, B. Ren, Paul Flicek, Ken Chen, M. Gerstein, P. Kwok, P. Lansdorp, Gabor T. Marth, J. Sebat, Xinghua Shi, A. Bashir, K. Ye, S. Devine, M. Talkowski, Ryan E. Mills, T. Marschall, J. Korbel, E. Eichler, Charles Lee   +89 more
semanticscholar   +1 more source