Results 41 to 50 of about 407,509 (363)

Natural polymorphism in the thrombospondin-related adhesive protein of Plasmodium falciparum [PDF]

, 1998
We have developed a typing system using natural sequence variation in the thrombospondin-related adhesive protein (TRAP) gene of Plasmodium falciparum. This method permits a haplotype to be assigned to any particular TRAP gene.
Bosman, Andrea, Crisanti, Andrea, Dolo, Amagana, Doumbo, Ogobara, Hackford, Ian R., Keita, Mamadou M., Modiano, David, Richards, Martin B., Robson, Kathryn J.H., Sidibe, Touman   +9 more
core   +1 more source

A Genetic Make Up of Italian Lipizzan Horse Through Uniparental Markers to Preserve Historical Pedigrees

Biology
Lipizzan is a famous horse breed dating back to 1580 when the original stud of Lipica was established by the Hasburg Archduke Charles II. Currently, the Italian State Stud of Lipizzan Horses (ASCAL) is a conservation nucleus managed through strict mating
Alessandra Crisà, Irene Cardinali, Andrea Giontella, Maurizio Silvestrelli, Hovirag Lancioni, Luca Buttazzoni   +5 more
doaj   +1 more source

The Path to Conserved Extended Haplotypes: Megabase-Length Haplotypes at High Population Frequency

Frontiers in Genetics, 2021
This minireview describes the history of the conceptual development of conserved extended haplotypes (CEHs): megabase-length haplotypes that exist at high (≥0.5%) population frequency.
Chester A. Alper, Chester A. Alper
doaj   +1 more source

What Is the Role of Giant Endosomal Sorting Complexes Required for Transport (ESCRT) Structures in T Cell Activation?

Advanced Biology, EarlyView.
The article explores the discovery of unusually large, ring‐shaped ESCRT protein structures formed by immune and stromal cells. It investigates their formation, composition, and potential roles in immune synapse formation. The findings challenge assumptions about their function in immunological synapses, suggesting an exclusive role in maintaining ...
Anthi Psoma, Femmy C. Stempels, Rinse de Boer, Geert van den Bogaart   +3 more
wiley   +1 more source

Phospholipase C epsilon 1 (PLCE1) haplotypes are associated with increased risk of gastric cancer in Kashmir Valley

The Saudi Journal of Gastroenterology, 2014
Background/Aim: Phospholipase C epsilon 1 (PLCE1) plays a crucial role in carcinogenesis and progression of several types of cancers. A single nucleotide polymorphism (SNP, rs2274223) in PLCE1 has been identified as a novel susceptibility locus.
Manzoor A Malik, Priya Srivastava, Showkat A Zargar, Balraj Mittal   +3 more
doaj   +1 more source

The dynamics of alternative pathways to compensatory substitution [PDF]

, 2013
The role of epistatic interactions among loci is a central question in evolutionary biology and is increasingly relevant in the genomic age. While the population genetics of compensatory substitution have received considerable attention, most studies ...
Nasrallah, Chris A.
core   +2 more sources

De novo assembly of haplotype-resolved genomes with trio binning

Nature Biotechnology, 2018
Complex allelic variation hampers the assembly of haplotype-resolved sequences from diploid genomes. We developed trio binning, an approach that simplifies haplotype assembly by resolving allelic variation before assembly.
S. Koren, A. Rhie, B. Walenz, A. Dilthey, D. Bickhart, S. Kingan, S. Hiendleder, J. Williams, T. Smith, A. Phillippy   +9 more
semanticscholar   +1 more source

High‐Resolution Genomic Resources for Trait Mapping and Precision Breeding for Adzuki Bean (Vigna angularis)

Advanced Science, EarlyView.
This study establishes crucial genomic resources for adzuki bean, including a reference genome, variation map, and the AdzukiBeanAtlas toolkit. We identify key candidate genes (ANKRD50, NAC73, ANR1, NPF5.4) for important agronomic traits through Genome‐Wide Association Studies (GWAS).
Liangliang Hu, Xiaolei Wang, Yazhou Zhang, Vanika Garg, Xingxing Yuan, Renfeng Xue, Hongmei Zhou, Yanhua Chen, Weili Hu, Rutwik Barmukh, Rong Cao, Tianxiao Chen, Qiannan Song, Dan Gao, Gaoling Luo, Xu Zhu, Xin Jing, Suhua Wang, Caiju Li, Yunshan Wei, Weide Ge, Xin Chen, Lixia Wang, Rajeev K Varshney, Chengzhi Jiao, Xuzhen Cheng, Honglin Chen   +26 more
wiley   +1 more source

A genome-wide combinatorial strategy dissects complex genetic architecture of seed coat colour in chickpea

Frontiers in Plant Science, 2015
The study identified 9045 high-quality SNPs employing both genome-wide GBS- and candidate gene-based SNP genotyping assays in 172, including 93 cultivated (desi and kabuli) and 79 wild chickpea accessions.
Deepak eBajaj, Shouvik eDas, Hari Deo eUpadhyaya, Rajeev eRanjan, Rajeev eRanjan, SAURABH eBADONI, Vinod eKumar, Shailesh eTripathi, CL Laxmipathi Gowda, Shivali eSharma, Sube eSingh, Akhilesh eTyagi, SWARUP KUMAR PARIDA   +12 more
doaj   +1 more source

U‐Shaped Response of Flowering Time to Low and High Nitrogen via a Transcription Feedback Loop in Rice

Advanced Science, EarlyView.
The “seesaw effect” of Nhd1‐Ghd7 module in regulating flowering time (days to heading in rice) responses to nitrogen (N) via Hd3a/RFT1: deficient‐N (DN) delays flowering via Ghd7‐mediated suppression of Nhd1; moderate‐N (MN) impairs this suppression, enhancing Nhd1 to promote flowering; whereas superior‐N (SN) delays flowering by Nhd1‐activated ...
Shunan Zhang, Guanzhong Shou, Xianping Li, Xuemin Song, Xuesong Li, Junjie Guo, Jiaqiang Lu, Yi Jin, Hongye Qu, Ming Yan, Wona Ding, Ying Liu, Guohua Xu   +12 more
wiley   +1 more source