Results 141 to 150 of about 28,399 (219)

Continental accumulation of fads2 copy numbers allows sticklebacks to thrive across a diversity of nutritional landscapes

open access: yesOikos, EarlyView.
Nutrients, including vital organic compounds, vary in availability across ecosystems, with the potential to act as a source of selection for traits that increase nutrient acquisition and biosynthesis. Compared to freshwaters, marine ecosystems are richer in the omega‐3 long‐chain polyunsaturated fatty acid (n‐3 LC‐PUFA) docosahexaenoic acid (DHA ...
Cornelia W. Twining   +12 more
wiley   +1 more source

Optical mapping reveals a higher level of large‐scale structural variants in a family with paternally transmitted myotonic dystrophy and independent Parkinson's disease

open access: yesThe Journal of Pathology, EarlyView.
Abstract Myotonic dystrophy type 1 (DM1) is a clinically challenging multisystem neuromuscular hereditary disorder, with generational increase in severity and earlier age at onset. It is caused by an unstable cytosine‐thymine‐guanine repeat expansion at the DMPK locus, accompanied by associated genetic and epigenetic modifications.
Md Mehedi Hasan   +9 more
wiley   +1 more source

Engineering compact Physalis peruviana (goldenberry) to promote its potential as a global crop

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Goldenberry (Physalis peruviana) produces sweet, nutritionally rich berries, yet like many minor crops, is cultivated in limited geographical regions and has not been a focus of breeding programs for trait enhancement. Leveraging knowledge of plant architecture‐related traits from related species, we used CRISPR/Cas9‐mediated gene editing to generate a
Miguel Santo Domingo   +8 more
wiley   +1 more source

Speciation with gene flow

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Biodiversity is threatened by human activities, with extinction debt accumulating rapidly. Many of these activities change the connectivity of populations, fragmenting existing population systems or bringing previously isolated populations or species into contact.
Zhiqin Long   +7 more
wiley   +1 more source

A synthetic eco‐evolutionary proposal for the conservation of wild relatives of the olive tree

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Societal Impact Statement Crop wild relatives (CWR) are valuable sources of genetic diversity for plant breeding. However, the identification of wild untapped genetic resources (i.e., unexploited in crops) is not always straightforward. We propose a methodology to guide the identification and conservation of these resources that integrates both genetic
Andrés Barea‐Márquez   +6 more
wiley   +1 more source

Gene turnover in the common ancestor of all C4 grasses

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
Understanding how plants evolve more efficient photosynthesis is important in a warming world where improving crop productivity and resilience is a global priority. By generating the first reference genomes for an early‐diverging group of grasses called the Aristidoideae, we were able to reconstruct the genetic makeup of the last common ancestor of all
Lara Pereira   +6 more
wiley   +1 more source

Haplotype Inference with Boolean Constraint Solving: An Overview

open access: yes, 2008
Ana Graça   +7 more
core   +1 more source

Bayesian Hierarchical Generalized Linear Models For Detecting (Rare) Haplotype-Haplotype And Haplotype-Environment Interactions In Genetic Association Analysis

open access: yes, 2011
This dissertation research focuses on genetic association analysis based on haplotypes in the context of both population-based and family-based studies. Haplotype-based association analysis is powerful in the discovery and characterization of the genetic
Li, Jun
core  

From wild to tamed: Reimagining novel crops through omics and local plant diversity

open access: yesPLANTS, PEOPLE, PLANET, EarlyView.
The global food system faces growing pressure from climate change, biodiversity loss, and rising nutritional demands. Agriculture has increased yields but reduced crop diversity, flavor, and nutritional quality, leaving societies vulnerable and dependent on a narrow set of staple species.
Alexandra Sanfeliu Meliá   +1 more
wiley   +1 more source

SAT in Bioinformatics: Making the Case with Haplotype Inference

open access: yes, 2006
Marques-Silva, Joao   +3 more
core   +1 more source

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