Results 11 to 20 of about 28,399 (219)

Exploring effective approaches for haplotype block phasing

BMC Bioinformatics, 2019
Background Knowledge of phase, the specific allele sequence on each copy of homologous chromosomes, is increasingly recognized as critical for detecting certain classes of disease-associated mutations. One approach for detecting such mutations is through
Ziad Al Bkhetan, Justin Zobel, Adam Kowalczyk, Karin Verspoor, Benjamin Goudey   +4 more
doaj   +1 more source

Haplotype reconstruction error as a classical misclassification problem [PDF]

, 2008
Statistically reconstructing haplotypes from single nucleotide polymorphism (SNP) genotypes, can lead to falsely classified haplotypes. This can be an issue when interpreting haplotype association results or when selecting subjects with certain ...
Heid, Iris M., Küchenhoff, Helmut, Lamina, Claudia, Bongardt, Friedhelm   +3 more
core   +1 more source

The Evolutionary Landscape of SARS-CoV-2 Variant B.1.1.519 and Its Clinical Impact in Mexico City

Viruses, 2021
The SARS-CoV-2 pandemic is one of the most concerning health problems around the globe. We reported the emergence of SARS-CoV-2 variant B.1.1.519 in Mexico City.
Alberto Cedro-Tanda, Laura Gómez-Romero, Nicolás Alcaraz, Guillermo de Anda-Jauregui, Fernando Peñaloza, Bernardo Moreno, Marco A. Escobar-Arrazola, Oscar A. Ramirez-Vega, Paulina Munguia-Garza, Francisco Garcia-Cardenas, Mireya Cisneros-Villanueva, Jose L. Moreno-Camacho, Jorge Rodriguez-Gallegos, Marco A. Luna-Ruiz Esparza, Miguel A. Fernández Rojas, Alfredo Mendoza-Vargas, Juan Pablo Reyes-Grajeda, Abraham Campos-Romero, Ofelia Angulo, Rosaura Ruiz, Claudia Sheinbaum-Pardo, José Sifuentes-Osornio, David Kershenobich, Alfredo Hidalgo-Miranda, Luis A. Herrera   +24 more
doaj   +1 more source

QTL mapping reveals candidate genes for main agronomic traits in Luffa based on a high-resolution genetic map

Frontiers in Plant Science, 2022
Luffa is an important medicinal and edible vegetable crop of Cucurbitaceae. Strong heterosis effects and strikingly complementary characteristics were found between the two domesticated Luffa cultivars, Luffa acutangula and Luffa cylindrica.
Lili Liu, Yaqin Gan, Yaqin Gan, Jianning Luo, Jianning Luo, Junxing Li, Xiaoming Zheng, Hao Gong, Xiaoxi Liu, Liting Deng, Gangjun Zhao, Haibin Wu, Haibin Wu   +12 more
doaj   +1 more source

Characterization of Myanmar Paw San Hmwe Accessions Using Functional Genetic Markers

Rice Science, 2015
Paw San Hmwe (PSM) rice has been cultivated in many areas of Myanmar for a long time. Strong aroma, good taste and its elongation during cooking are the key characteristics of PSM rice.
Kyaw Swar Oo, Alisa Kongjaimun, Srisawat Khanthong, Myint Yi, Tin Tin Myint, Siriporn Korinsak, Jonaliza Lanceras Siangliw, Khin Myo Myint, Apichart Vanavichit, Chanate Malumpong, Theerayut Toojinda   +10 more
doaj   +1 more source

Fusarium Species Associated with Maize Leaf Blight in Heilongjiang Province, China

Journal of Fungi, 2022
Fusarium spp. are among the most important plant pathogens in the world. A survey on maize leaf blight was carried out in Heilongjiang province from 2019 to 2021.
Xi Xu, Li Zhang, Xilang Yang, Guijin Shen, Shuo Wang, Haolin Teng, Chunbo Yang, Xueyan Liu, Xiangjing Wang, Junwei Zhao, Wensheng Xiang   +10 more
doaj   +1 more source

Robust Preimplantation Genetic Testing Strategy for Myotonic Dystrophy Type 1 by Bidirectional Triplet-Primed Polymerase Chain Reaction Combined With Multi-microsatellite Haplotyping Following Whole-Genome Amplification

Frontiers in Genetics, 2019
Myotonic dystrophy type 1 (DM1) is caused by expansion of the DMPK CTG trinucleotide repeat. Disease transmission to offspring can be avoided through prenatal diagnosis or preimplantation genetic testing for monogenic disorders (PGT-M).
Mulias Lian, Caroline G. Lee, Caroline G. Lee, Caroline G. Lee, Samuel S. Chong, Samuel S. Chong, Samuel S. Chong   +6 more
doaj   +1 more source

CLCC1 c. 75C>A Mutation in Pakistani Derived Retinitis Pigmentosa Families Likely Originated With a Single Founder Mutation 2,000–5,000 Years Ago

Frontiers in Genetics, 2022
Background: A CLCC1 c. 75C > A (p.D25E) mutation has been associated with autosomal recessive pigmentosa in patients in and from Pakistan. CLCC1 is ubiquitously expressed, and knockout models of this gene in zebrafish and mice are lethal in the ...
Yan Ma, Xun Wang, Xun Wang, Nadav Shoshany, Nadav Shoshany, Xiaodong Jiao, Adrian Lee, Gregory Ku, Emma L. Baple, Emma L. Baple, James Fasham, James Fasham, Raheela Nadeem, Muhammad Asif Naeem, Sheikh Riazuddin, Sheikh Riazuddin, S. Amer Riazuddin, Andrew H. Crosby, J. Fielding Hejtmancik   +18 more
doaj   +1 more source

Combining Genome-Wide Association Study and Gene-Based Haplotype Analysis to Identify Candidate Genes for Alkali Tolerance at the Germination Stage in Rice

Frontiers in Plant Science, 2022
Salinity–alkalinity stress is one of the main abiotic factors limiting rice production worldwide. With the widespread use of rice direct seeding technology, it has become increasingly important to improve the tolerance to salinity–alkalinity of rice ...
Song Mei, Guogen Zhang, Jing Jiang, Jingbing Lu, Fan Zhang, Fan Zhang, Fan Zhang   +6 more
doaj   +1 more source

Genome-Wide Analyses Reveal Footprints of Divergent Selection and Drought Adaptive Traits in Synthetic-Derived Wheats

G3: Genes, Genomes, Genetics, 2019
Crop-wild introgressions have long been exploited without knowing the favorable recombination points. Synthetic hexaploid wheats are one of the most exploited genetic resources for bread wheat improvement.
Fakiha Afzal, Huihui Li, Alvina Gul, Abid Subhani, Ahmad Ali, Abdul Mujeeb-Kazi, Francis Ogbonnaya, Richard Trethowan, Xianchun Xia, Zhonghu He, Awais Rasheed   +10 more
doaj   +1 more source