Results 11 to 20 of about 256,625 (325)

Joint Haplotype Assembly and Genotype Calling via Sequential Monte Carlo Algorithm [PDF]

, 2015
Genetic variations predispose individuals to hereditary diseases, play important role in the development of complex diseases, and impact drug metabolism. The full information about the DNA variations in the genome of an individual is given by haplotypes,
Ahn, Soyeon, Vikalo, Haris
core   +3 more sources

Functional Analysis of Haplotypes in Bovine PSAP Gene and Their Relationship with Beef Cattle Production Traits

Animals, 2020
The purpose of this study was to explore functional variants in the prosaposin (PSAP) three prime untranslated region (3’ UTR) and clarify the relationship between the variants and morphological traits.
Haidong Zhao, Mingli Wu, Xiaohua Yi, Xiaoqin Tang, Pingbo Chen, Shuhui Wang, Xiuzhu Sun   +6 more
doaj   +1 more source

Genetic Differentiation and Population Structure of Threatened Prunus africana Kalm. in Western Cameroon Using Molecular Markers

Diversity, 2020
Genetic diversity of species is an important baseline for the domestication process. In Cameroon, Prunus africana, an important and threatened medicinal tree, is among the priority species for domestication.
Justine G. Nzweundji, Ulrike Huewe, Nicolas Niemenak, Néhémie T. Donfagsiteli, Klaus Eimert   +4 more
doaj   +1 more source

Viral population estimation using pyrosequencing [PDF]

, 2008
The diversity of virus populations within single infected hosts presents a major difficulty for the natural immune response as well as for vaccine design and antiviral drug therapy.
A Dempster, A Rambaut, AMN Tsibris, B Gaschen, Baback Gharizadeh, C Wang, Chunlin Wang, D O'Meara, DC Douek, E Domingo, E Halperin, EH Simpson, ES Lander, Glenn Tesler, GS Gottlieb, GW Tyson, H Fakhrai-Rad, I Malet, IM Rouzine, J Kececioglu, JE Hopcroft, JF Simons, K Chen, KJ Metzner, L Bacheler, L Doukhan, L Excoffier, Lior Pachter, LR Ford, M Breitbart, M Eigen, M Margulies, M Stephens, MA Nowak, MJ Gonzales, ML Collins, ML Sogin, Mostafa Ronaghi, MT Tammi, N Beerenwinkel, Nicholas Eriksson, Niko Beerenwinkel, P Jenkins, PA Pevzner, R Schmid, R Shankarappa, Robert W. Shafer, RP Dilworth, S Huse, S-Y Rhee, S-Y Rhee, Soo-Yon Rhee, VA Johnson, Yumi Mitsuya   +53 more
core   +7 more sources

Barcoding of the cytochrome oxidase I (COI) indicates a recent introduction of Ciona savignyi into New Zealand and provides a rapid method for Ciona species discrimination [PDF]

, 2012
Mitochondrial cytochrome oxidase I (COI) gene sequencing (DNA barcoding) of Ciona specimens from New Zealand (NZ) led to the first record of the solitary ascidian Ciona savignyi in the Southern Hemisphere. We sought to quantify C.
Cary, S. Craig, Fidler, Andrew E., Gemmill, Chrissen E.C., Smith, Kirsty Fiona, Thia, Joshua   +4 more
core   +2 more sources

Accurate Allele Frequencies from Ultra-low Coverage Pool-Seq Samples in Evolve-and-Resequence Experiments

G3: Genes, Genomes, Genetics, 2019
Evolve-and-resequence (E+R) experiments leverage next-generation sequencing technology to track the allele frequency dynamics of populations as they evolve.
Susanne Tilk, Alan Bergland, Aaron Goodman, Paul Schmidt, Dmitri Petrov, Sharon Greenblum   +5 more
doaj   +1 more source

Minimum error correction-based haplotype assembly: considerations for long read data

, 2020
The single nucleotide polymorphism (SNP) is the most widely studied type of genetic variation. A haplotype is defined as the sequence of alleles at SNP sites on each haploid chromosome.
de Ridder, Dick, Kahaei, Mohammad Hossein, Majidian, Sina   +2 more
core   +1 more source

Sensitivity towards DMI fungicides and haplotypic diversity of their CYP51 target in the Mycosphaerella graminicola population of Flanders [PDF]

, 2014
Septoria leaf blotch, caused by the fungus Mycosphaerella graminicola, is the most important wheat disease in Northwestern Europe, and is currently controlled by fungicide applications.
Curvers, Katrien, Gheysen, Godelieve, Haesaert, Geert, Kyndt, Tina, Pycke, Bart   +4 more
core   +1 more source

Polymorphisms of MicroRNA-146a Gene in Behcet’s Disease in Iraqi Patients

Journal of Pure and Applied Microbiology, 2018
The present study was carried out to detect the association of miR-146a haplotypes polymorphisms with Behcet’s Disease in Iraqi patients, PCR-SSCP technique used in present study, blood was used to DNA extraction, the results show that there was strong
Israa Harjan Mohsen, Mona N. Al-Terehi, Abbas Hussein Mugheer, Ahmed Al-Hachamy, Ali H. Al-Saadi   +4 more
doaj   +1 more source

Haplotypes of [‐794(CATT)5–8/‐173G>C] MIF gene polymorphisms and its soluble levels in cutaneous squamous cell carcinoma in western Mexican population

Molecular Genetics & Genomic Medicine, 2023
Background Some cytokines are strongly implicated in the development of squamous cell carcinoma (SCC) such as the Macrophage migration inhibitory factor (MIF).
Elizabeth Guevara‐Gutiérrez, Marina Ramos‐Súarez, Romina Angélica Villalobos‐Ayala, Alberto Tlacuilo‐Parra, José Francisco Muñoz‐Valle, Victor Tarango‐Martínez, Yeminia Valle, Jorge Ramón Padilla‐Gutiérrez, José Manuel Rojas‐Díaz, Emmanuel Valdés‐Alvarado   +9 more
doaj   +1 more source