Results 81 to 90 of about 175,373 (307)

ACE haplotypes.

, 2018
ACE haplotypes.
Clarence C. Gravlee (370512), Kia C. Fuller (5759408), Connie J. Mulligan (39895), Christopher McCarty (3859360), Cynthia Seaborn (5759411)   +4 more
core   +1 more source

Resolving the biome debate: ecological and palaeo‐data concur that the extensive tree‐limited grassy biomes of central and north‐western Madagascar are largely anthropogenic

Biological Reviews, EarlyView.
ABSTRACT For millennia, human activities have transformed ecosystems globally. Determining which landscapes are predominantly anthropogenic is crucial to conservation and habitat restoration. Madagascar, a critically‐threatened biodiversity hotspot, is a prominent example.
Grant S. Joseph, Sean Hixon, Colleen L. Seymour, Laurie R. Godfrey, Miguel Pedrono, Karen E. Samonds, Andrinajoro R. Rakotoarivelo, Brooke E. Crowley   +7 more
wiley   +1 more source

Genesis of ancestral haplotypes: RNA modifications and reverse transcription–mediated polymorphisms [PDF]

, 2011
Understanding the genesis of the block haplotype structure of the genome is a major challenge. With the completion of the sequencing of the Human Genome and the initiation of the HapMap project the concept that the chromosomes of the mammalian genome are
Stewart, B.J., Carnegie, P., Pain, G.N., Dawkins, R.L., Steele, E.J., Williamson, J.F., Lindley, R.A., Millman, J.A., Lester, S.   +8 more
core  

The Effect of Dicloxacillin Administration on Pharmacokinetics of Narrow Therapeutic Window Drugs: Phenytoin and Warfarin

Clinical Pharmacology &Therapeutics, EarlyView.
Dicloxacillin is a penicillinase‐resistant beta‐lactam antibiotic and potent activator of the Pregnane X receptor (PXR), known to induce CYP2C9, CYP2C19, and CYP3A4 activity. Clinical data suggest it reduces anticoagulation in warfarin‐treated patients and increases the risk of thromboembolic events.
Chanan Shaul, Waseem Mujahed, Ibrahim Idries, Maor Wanounou, Meir Bialer, Yoseph Caraco   +5 more
wiley   +1 more source

Frequency of haplotypes in TAS2R38 gene (with rare haplotypes*).

Frequency of haplotypes in TAS2R38 gene (with rare haplotypes*).
Dorota Łukasiewicz-Śmietańska (18468786), Andrzej Szpak (18468792), Dorothy Rybaczyk-Pathak (18468801), Elżbieta Chabros (18468795), Jadwiga Charzewska (18468798), Dariusz Godlewski (18468789), Grzegorz Juszczyk (4428073), Elżbieta Nowakowska (3797737)   +7 more
core   +1 more source

Screening tests for Disease Risk Haplotype Segments in Genome by Use of Permutation [PDF]

, 2015
The haplotype association analysis has been proposed to capture the collective behavior of sets of variants by testing the association of each set instead of individual variants with the disease.
Ali, Fadhaa, Zhang, Jian
core  

RAD haplotypes

, 2018
Data corresponding to the RAD-tags ("RAD haplotypes" in the ...
Gaggiotti, Oscar E., Mouterde, Médéric, Pierre de Villemereuil (5893718), Oscar E. Gaggiotti (3191232), Irène Till-Bottraud (5014292), Médéric Mouterde (7068389), de Villemereuil, Pierre, Till-Bottraud, Irène   +7 more
core   +1 more source

UMOD Genotype and Clinical Outcomes in Heart Failure Patients Treated with Loop Diuretics: A UK Biobank Pharmacogenetic Cohort Study

Clinical Pharmacology &Therapeutics, EarlyView.
Uromodulin (UMOD) regulates tubular sodium handling and modulates NKCC2, the molecular target of loop diuretics (LD). Although UMOD variants have been associated with blood pressure and hypertension, their pharmacogenetic relevance in heart failure (HF) remains unknown.
Reinhold Kreutz, Pimrapat Gebert, Jingwen Luo, Paraskevi Tassopoulou, Juliane Bolbrinker, Antonios Douros   +5 more
wiley   +1 more source

Statistical parsimony haplotypes network.

, 2016
Haplotype network showing the relationships between modern haplotypes and haplotypes observed in the archaeological samples analysed in the present study (indicated by asterisks).
Tatiana Fioravanti (2609869), Luigi Olivieri (3164667), Vincenzo Caputo Barucchi (766210), Paolo Ruggeri (2609866), Massimo Giovannotti (766212), Alessandra Negri (3164670), Paola Nisi Cerioni (2609851), Massimo Lorenzoni (3164664), Andrea Splendiani (31113)   +8 more
core   +1 more source

Characterization of NAT2 Using Long‐Read Sequencing: Allele, Diplotype, and Phenotype Call Accuracy Compared to Other Testing Strategies

Clinical Pharmacology &Therapeutics, EarlyView.
The NAT2 pharmacogene is essential in drug metabolism, particularly for aromatic amines and hydrazines. Genetic variations in NAT2 categorize individuals as rapid, intermediate, or poor metabolizers based on their acetylation capacity to inform dosing guidelines.
Shobana John, Erin C. Boone, Byunggil Yoo, Laura B. Ramsey, Andrea Gaedigk   +4 more
wiley   +1 more source