Results 121 to 130 of about 38,975 (198)

Chitinases in Tear Fluid of Patients With Amyotrophic Lateral Sclerosis

European Journal of Neurology, Volume 33, Issue 9, September 2026.
This study investigated chitinase expression in ALS across tear fluid (TF), CSF, and serum. CHI3L1 was elevated in TF, consistent with changes in CSF, but not serum. Furthermore, combining TF chitinases with serum NfL improved diagnostic discrimination.
Lara Wenz, Lena‐Sophie Scholl, Nya Reinhardt, Ricarda von Heynitz, Vincent Gmeiner, Petra Rau, Philipp Jie Müller, Andreas W. Wolff, Emily Feneberg, Antonia F. Demleitner, Paul Lingor   +10 more
wiley   +1 more source

Haptoglobins and hemoglobin-haptoglobin complexes

, 1970
Haptoglobins are serum glycoproteins which form complexes with hemoglobin. Three phenotypes of haptoglobin exist in serum (Hp 1-1, Hp 2-1, Hp 2-2). The latter two types exist as a series of polymers while the former type exists as a homogeneous protein ...
Malchy, Barry L.
core   +1 more source

Combating ageing beyond the cell: Emerging roles of extracellular proteostasis

The FEBS Journal, Volume 293, Issue 18, Page 5558-5584, September 2026.
Ageing challenges the body's ability to maintain a stable and functional proteome, leading to protein damage and aggregation both inside and outside cells. This review focuses on the less well understood mechanisms of extracellular protein quality control and how they become disrupted in ageing, particularly in neurodegenerative diseases.
Siddharth R. Venkatesh, Ivan Gallotta, Bolanle F. Olabiyi, Yoon Hee Choi, Sarah Inglesfield, Janet R. Kumita, Collin Y. Ewald, Della C. David   +7 more
wiley   +1 more source

Neutrophil Secretory Proteins Inhibit Calcium Oxalate Crystallisation and Crystal Growth, but Promote Crystal Aggregation

Immunology, Volume 179, Issue 1, Page 101-117, September 2026.
Calcium oxalate monohydrate (COM) crystals cause changes in the secretion of 29 proteins from neutrophil‐like cells, including those involved in neutrophil immune activation and intracellular metabolic adaptation. The neutrophil secreted proteins (secretome) also inhibit calcium oxalate crystallisation and crystal growth, but promote crystal ...
Chanettee Lertprapai, Paleerath Peerapen, Visith Thongboonkerd   +2 more
wiley   +1 more source

AI‐Assisted Literature Mining Reveals Spatiotemporal Heterogeneity and Progression Trajectories of Traditional Chinese Medicine Syndromes in Coronary Heart Disease in China

Journal of Evidence-Based Medicine, Volume 19, Issue 3, September 2026.
ABSTRACT Despite the centrality of syndrome differentiation in guiding personalized traditional Chinese medicine (TCM) interventions for coronary heart disease (CHD), existing studies of TCM syndrome distribution are constrained by fragmented methodologies and limited spatiotemporal resolution. In this study, we employed an artificial intelligence (AI)‐
Qianzi Che, Tian Song, Zhaoyuan Gong, Chuxuan Wang, Bin Liu, Mingzhi Hu, Ning Liang, Haili Zhang, Huizhen Li, Qingyang Zeng, Lin Chen, Yuanming Leng, Xihao Cao, Jing Wan, Jing Guo, Nannan Shi   +15 more
wiley   +1 more source

Therapeutic potential of haptoglobin in a murine model of sickle cell anemia. [PDF]

PLoS One
Dos Santos BC, Dos Santos MNN, Pedroso GA, de Oliveira BB, de Albuquerque DM, de Oliveira NR, Noronha DC, Costa FF, Corat MAF.   +8 more
europepmc   +1 more source

Elevated Serum Soluble CD163 Indicates Macrophage Activation: A Potential Biomarker for Inflammation in Complex Regional Pain Syndrome?

Pain Practice, Volume 26, Issue 7, September 2026.
ABSTRACT Background Several studies point towards the involvement of the immune system (especially the monocyte–macrophage system) in the pathophysiology of Complex Regional Pain Syndrome (CRPS), as shown by increased levels of the cytokines tumor necrosis factor (TNF)‐α and interleukin (IL)‐6.
Nadia Kriek, Krishna Bharwani, Maaike Dirckx, Dirk Stronks, Nicole Nagtzaam, Wim A. Dik, Frank Huygen   +6 more
wiley   +1 more source

Comparative Assessment of Cortisol, Leptin, Haptoglobin and Inflammatory Interleukins in Modicana and Holstein Cows During the Peripartum Period. [PDF]

Animals (Basel)
Arrigo F, Rizzo M, Sisia G, Giannetto C, Giudice E, Piccione G, Arfuso F.   +6 more
europepmc   +1 more source

GLUT1 Deficiency Syndrome with Coexistent Movement Disorder and Anemia

Movement Disorders Clinical Practice, Volume 13, Issue 9, Page 2281-2283, September 2026.
Sangeetha Yoganathan, Haya S AlFaris, Anika Menetrey, Sayoni Roy Chowdhury, Lindsey Vogt, Jolynn Dickson, Karen Owusu, Pradeep Krishnan, Suvasini Sharma, Liali Aljouda, Reena Pabari, Grace Yoon, Carolina Gorodetsky   +12 more
wiley   +1 more source

Interleukin-6 as an Oral-Vascular Inflammatory Bridge: Integrating CXCL10 and Haptoglobin 2-2 into a Potential Model of Periodontitis-Associated Cardiovascular Risk. [PDF]

Int J Mol Sci
Vigerust DJ, Bale BF.
europepmc   +1 more source