Results 81 to 90 of about 37,781 (227)

Neuropathological and cerebrospinal fluid correlates of choroid plexus inflammation in progressive multiple sclerosis

Brain Pathology, EarlyView.
Graphical representation of the widespread white matter (blue color mask) and grey matter (cortical and deep grey matter; red color mask) demyelination in MS cases characterized by substantial inflammation of the CP (A). The presence of lesions was mainly associated with periventricular white matter and hippocampus areas (A).
R. Magliozzi, S. Hametner, M. Mastantuono, A. Mensi, M. Karimian, L. Griffiths, L. M. Watkins, A. Poli, G. M. Berti, E. Barusolo, B. Bellini, S. Rossi, D. Gveric, J. A. Stratton, K. Akassoglou, S. Magon, R. Nicholas, R. Reynolds, O. W. Howell, S. Monaco   +19 more
wiley   +1 more source

Haptoglobin Genotypes in Hidradenitis Suppurativa: Haptoglobin 2–2 Genotype Is Associated With Familial Hidradenitis Suppurativa and More Flares

International Journal of Dermatology, EarlyView.
ABSTRACT Background Haptoglobin (Hp) is an acute‐phase protein and an independent marker for hidradenitis suppurativa (HS) severity. The different Hp genotypes (Hp 1–1, Hp 1–2, and Hp 2–2) differ in their antioxidant and anti‐inflammatory functions. Hp genotypes have never been investigated in HS patients.
Nessr Abu Rached, Marina Skrygan, Lennart Ocker, Yannik Haven, Daniel Myszkowski, Eggert Stockfleth, Falk G. Bechara   +6 more
wiley   +1 more source

Exploring Haptoglobin as a Promising Marker for Severe Liver Diseases: A Comprehensive Review

Quality in Sport
Liver damage is a common symptom of many diseases, including metabolic disorders and cancers. Such patient condition requires effective examinations aimed at prompt diagnosis and implementation of the most appropriate treatment for a specific disease ...
Daria Ziemińska, Rafał Burczyk, Wiktor Wardyn, Martyna Michalska, Karolina Winiarek, Joanna Murawska, Cezary Guzowski, Kornelia Kędziora-Kornatowska   +7 more
doaj   +1 more source

Serum Biomarkers in Atlantic Salmon for Differential Diagnosis of Cardiomyopathy Syndrome and Pancreas Disease: Proteomic Identification of Serum Fibrinogen to Enhance Troponin Immunoassay as Optimal Diagnostic Approach

Journal of Fish Diseases, EarlyView.
ABSTRACT Cardiac viral diseases are among the major causes of economic losses in Atlantic salmon (Salmo salar L.) aquaculture. These include cardiomyopathy syndrome (CMS) caused by piscine myocarditis virus (PMCV) and pancreas disease (PD) caused by Atlantic salmonid alphavirus (SAV).
Francesca Riva, Lauren Elaine Black, Kim D. Thompson, Philippe Sourd, Andrei Bordeianu, Christopher C. Chadwick, Hooman Moghadam, Jorge Del‐Pozo, Janina Costa, Richard Burchmore, Nicola Brady, Lewis Moore, Suzanne McGill, Mark McLaughlin, Peter David Eckersall   +14 more
wiley   +1 more source

Proteomic analysis of plasma proteins during fentanyl withdrawal in ovariectomized female rats with and without estradiol

Journal of Neuroendocrinology, EarlyView.
Abstract Evidence from both clinical and preclinical studies indicates that females experience a faster progression to drug addiction and more severe addiction‐related health effects compared with males. Estradiol (E2) plays a critical role in these sex differences.
Patricia Sinclair, Navdeep S. Dhanjal, E. Blair Towers, Wendy J. Lynch, Nadine Kabbani   +4 more
wiley   +1 more source

Endothelial dysfunction inhibits the ability of haptoglobin to prevent hemoglobin-induced hypertension.

American Journal of Physiology. Heart and Circulatory Physiology, 2017
Intravascular hemolysis produces injury in a variety of human diseases including hemoglobinopathies, malaria, and sepsis. The adverse effects of increased plasma hemoglobin are partly mediated by depletion of nitric oxide (NO) and result in ...
Jan A. Graw, B. Yu, Emanuele Rezoagli, H. Shaw Warren, Emmanuel S Buys, Donald B. Bloch, Warren M. Zapol   +6 more
semanticscholar   +1 more source

Branching Out: Rabbit Models Provide Evidence for the Use of a Willow Cultivar (Salix miyabeana) as a Suitable Forage Material for Monogastric Herbivores in Zoos

Journal of Animal Physiology and Animal Nutrition, EarlyView.
ABSTRACT We assessed the suitability of a willow cultivar for monogastric herbivores in zoos using a rabbit model. Thirty‐six male New Zealand White × Californian rabbits at 5 weeks of age were provided with bark and leaf material from a willow cultivar, Salix miyabeana (SX61), in one of four treatments for 6 weeks: UC (unrestricted control of pelleted
Ben Martin, Anna K. Shoveller, Pauline A. L. Kosmal   +2 more
wiley   +1 more source

Identification of CD163 as an antiinflammatory receptor for HMGB1-haptoglobin complexes.

JCI Insight, 2016
Secreted by activated cells or passively released by damaged cells, extracellular HMGB1 is a prototypical damage-associated molecular pattern (DAMP) inflammatory mediator.
Huan Yang, Haichao Wang, Y. Levine, M. Gunasekaran, Yongjun Wang, M. Addorisio, Shu Zhu, Wei Li, Jianhua Li, D. D. de Kleijn, P. Olofsson, H. Warren, Mingzhu He, Y. Al-Abed, J. Roth, D. Antoine, S. Chavan, U. Andersson, K. Tracey   +18 more
semanticscholar   +1 more source

Salivary Proteomics for Detecting Novel Biomarkers of Periodontitis: A Systematic Review

Journal of Periodontal Research, EarlyView.
Untargeted salivary proteomics identified promising biological molecules consistently over‐ or under‐expressed in periodontitis patients compared to periodontally healthy subjects, but further targeted approaches are required for their validation. ABSTRACT Aim Salivary content is regarded as a powerful diagnostic window for oral and systemic diseases ...
Matteo Corana, Giacomo Baima, Giovanni Iaderosa, Francesco Franco, Jianjian Zhang, Giovanni Nicolao Berta, Federica Romano, Mario Aimetti   +7 more
wiley   +1 more source

Haptoglobin is dispensable for haemoglobin uptake by Trypanosoma brucei

Frontiers in Immunology
Haptoglobin is a plasma protein of mammals that plays a crucial role in vascular homeostasis by binding free haemoglobin released from ruptured red blood cells.
Eva Horáková, Eva Horáková, Marek Vrbacký, Martina Tesařová, Eva Stříbrná, Jan Pilný, Zuzana Vavrušková, Marie Vancová, Marie Vancová, Roman Sobotka, Roman Sobotka, Julius Lukeš, Julius Lukeš, Jan Perner   +13 more
doaj   +1 more source