Results 91 to 100 of about 110,960 (290)

Hydrodynamic Selection of Polymorphic Assembly Pathways in Plant Protein Amyloid Fibrils

Advanced Science, EarlyView.
Hydrodynamic conditions are revealed to govern polymorphic assembly of soy protein amyloid fibrils. Distinct flow‐induced drafting, kissing, and docking dynamics direct fibril growth into multiple morphologies, linking fluid mechanics with nanoscale assembly and enabling rational design of functional amyloid materials.
Zejian Xu, Pengfei Yang, Meng Li, Zichen Cao, Tian Lan, Yan Zhang, Weibiao Zhou, Lianzhou Jiang, Xiaonan Sui   +8 more
wiley   +1 more source

Tip60‐Mediated USP22 Lactylation Drives Glutamine Metabolic Reprogramming via SLC25A5 in TNBC

Advanced Science, EarlyView.
Tip60‐mediated USP22 K134 lactylation, stabilizing SLC25A5 to enhance glutamine metabolism and α‐KG secretion. The secreted α‐KG drives GPR91‐dependent M2 macrophage polarization, promoting triple‐negative breast cancer progression. Targeting this axis synergizes with CB‐839, offering a promising therapeutic strategy for TNBC.
Fang Zhen, Hongyi Wang, Ningzhi Zhang, Le Wang, Huiyuan Tian, Luxi Kang, Zhanpeng Liu, Jing Hu   +7 more
wiley   +1 more source

DUSP26 Regulated by YY1 Lactylation Couples Osteogenesis and Angiogenesis by Dephosphorylating PMPCB at Y141 and Activating Mitophagy in BMSCs

Advanced Science, EarlyView.
p300‐associated YY1 lactylation promotes DUSP26 expression in BMSCs. By regulating PMPCB phosphorylation and PINK1 processing, DUSP26 supports mitophagy, osteogenic differentiation, and pro‐angiogenic factor secretion. BMSC‐derived exosomes carrying a RUNX2 promoter‐driven DUSP26 plasmid favor osteogenic‐lineage transgene expression, partially ...
Yunpeng Lv, Feng Wu, Xiongjie Liang, Chong Liu, Wenhui Guo, Kejian Zhang, Jiawen Niu, Wenjie Jiang, Hongjian Xu, Anlong Jiang, Yang Zheng, Enming Yu, Xintao Wang, Jinglong Yan, Jingjun Xia, Chengchao Song   +15 more
wiley   +1 more source

ReLink: Reliable Deep Learning for Microscopic Motion Tracking

Advanced Science, EarlyView.
ReLink enables reliable trajectory linking in single‐particle tracking by integrating physics‐informed motion statistics with confidence‐based adaptive filtering. Across diverse simulated and experimental conditions, ReLink robustly reconstructs trajectories and preserves the fidelity of downstream analyses, enabling accurate characterization of ...
Yuan Jiang, Xiaochen Feng, Hongda Wei, Hao Sha, Hongpeng Wang, Min Zhang, Sanyang Han, Yongbing Zhang   +7 more
wiley   +1 more source

Long Noncoding RNA LINC00173 Contributes to the Growth, Invasiveness and Chemo-Resistance of Colorectal Cancer Through Regulating miR-765/PLP2 Axis

Cancer Management and Research, 2020
Yanhui Yu,1,* Xiuyun Lu,2,* Chuandong Yang,3 Fengxiang Yin4 1Physical Examination Center, The 2nd Affiliated Hospital of Harbin Medical University, Harbin 150081, People’s Republic of China; 2Department of Traditional Chinese Medicine, The 2nd ...
Yu Y, Lu X, Yang C, Yin F
doaj  

Harbin (China), street scene

, 1931
Harbin city - Manchuria. Vehicles for hire, Pristan [former section of Harbin].GrayscalePendleton nitrate negative, Box 10 of ...
Pendleton, Robert Larimore, 1890-1957
core  

Weak‑Solvation‑Mediated Localized High‑Concentration Electrolyte for Sodium Metal Batteries

Advanced Science, EarlyView.
A weak‑solvation strategy using MTBE as a fluorine‑free diluent constructs a localized high‑concentration structure, promoting FSI− coordination and forming an inorganic‑rich SEI. This enables stable cycling with high‑loading cathodes and pouch cells, offering a sustainable, PFAS‑free electrolyte for sodium metal batteries.
Hongxu Qu, Huihua Li, Jingxuan Wang, Mingxing Zhang, Yang Wang, Yuhang Meng, Sailei Shao, Stefano Passerini, Huang Zhang   +8 more
wiley   +1 more source

HISTORY OF PERIODICALS OF THE FIRST HALF OF THE 20th CENTURY BASED ON MUSEUM MATERIALS OF HARBIN

Вестник Волгоградского государственного университета. Серия 4. История, регионоведение, международные отношения
Introduction. The influence of the Chinese Eastern Railway on the development of the northeastern provinces of China, including the development of education, science, and periodicals in Heilongjiang Province, was enormous.
Alina Steblyanskaya, Maksim Vasiev
doaj   +1 more source

How Does Patient Capital Enhance Agribusiness Resilience? Evidence From Chinese Listed Agribusinesses

Agribusiness, EarlyView.
ABSTRACT In emerging economies where smallholder farming dominates agricultural production, agribusinesses serve as critical intermediaries linking smallholders to broader markets, and their resilience directly affects agricultural sustainability. Short‐term‐oriented capital is reluctant to adequately finance highly uncertain and cyclical agricultural ...
Siyuan Lyu, Jianling Qi, Liling Jiang, Ronghua Jin, Yuanhao Yu, Lingjing Zhang   +5 more
wiley   +1 more source

Precision Matters: Minor Concentration Deviations of DMSO May Cause Major Efficacy Shifts

Angewandte Chemie, EarlyView.
Low‐concentration dimethyl sulfoxide (DMSO) has long been regarded as biologically safe in drug discovery. However, increasing DMSO from 0.1% to 0.9% reduces photosensitizer PNA‐9 particle size from 657 nm to 260 nm, enhancing endocytosis and photodynamic therapy outcomes.
Sisi Yuan, Shang Zhu, Hang Song, Fei Wang, Zikai He, Sijie Chen, Engui Zhao   +6 more
wiley   +2 more sources