Results 91 to 100 of about 123,840 (297)

The Portuguese Port of Macao [cartographic material] : the new gateway to South China.

, 1922
Map of southeast China showing locations of industries, important villages in proximity to Macau.; "Logical port of transhipment for many South China districts. 40 miles from Hongkong and 80 miles from Canton.
Macau. Harbour Authority.
core  

Establishment of a humanized patient‐derived xenograft mouse model of high‐grade serous ovarian cancer for preclinical evaluation of combination immunotherapy

Molecular Oncology, EarlyView.
We have established a humanized orthotopic patient‐derived xenograft (Hu‐oPDX) mouse model of high‐grade serous ovarian cancer (HGSOC) that recapitulates human tumor–immune interactions. Using combined anti‐PD‐L1/anti‐CD73 immunotherapy, we demonstrate the model's improved biological relevance and enhanced translational value for preclinical ...
Luka Tandaric, Line Bjørge, Martine Rott Lode, Cecilie Fredvik Torkildsen, Pia Aehnlich, Rammah Elnour, Daniela Elena Costea, Lars Andreas Akslen, Liv Cecilie Vestrheim Thomsen, Emmet McCormack, Katrin Kleinmanns   +10 more
wiley   +1 more source

DISCUSSION. HARBOURS OF REFUGE. [PDF]

Minutes of the Proceedings of the Institution of Civil Engineers
n ...
Walker, J., Russell, J. S., Murray, J., Rendel, J. M., Rennie, Sir J.   +4 more
openaire   +1 more source

Darwin Harbour Region report cards 2009

, 2009
"This first series of Darwin Harbour region report cards describes the health of aquatic ecosystems across the harbour and its catchment. The report cards provide a snapshot of water quality and biological health, and show how these natural systems ...
Darwin Harbour Advisory Committee, Drewry, John, Fortune, Julia, Northern Territory. Department of Natural Resources, Environment, The Arts And Sport. Aquatic Health Unit   +3 more
core  

Hippo pathway at the crossroads of stemness and therapeutic resistance in breast cancer

Molecular Oncology, EarlyView.
Dysregulation of the Hippo pathway drives nuclear accumulation of YAP/TAZ, activating stemness‐related transcriptional programs that sustain breast cancer stemness and fuel therapeutic resistance across subtypes, underscoring Hippo signaling as a targetable vulnerability. Figure created and edited with BioRender.com.
Giulia Schiavoni, Antonella Palmese, Stefano Scalera, Laura Cipriani, Davide Mascolo, Patrizia Vici, Teresa Arcuri, Lorena Filomeno, Eriseld Krasniqi, Giovanni Blandino, Giulia Bon, Marcello Maugeri‐Saccà   +11 more
wiley   +1 more source

Wrice, Randy. 2. Part two of interview about the Harbour Grace Heritage District, Harbour Grace.

, 2022
Randy Wrice talks about the tourism potential of Harbour Grace's trails. He reminisces about when the town was booming pre-moratorium but expresses optimism about its future, thanks to new businesses, an enthusiastic heritage committee, summer ...
Caputo-Nimbark, Roshni, 1985-
core  

E2A selectively regulates TGF‐β–induced apoptosis in KRAS‐mutant non‐small cell lung cancer

Molecular Oncology, EarlyView.
Ability to induce apoptosis by TGF‐β is frequently lost in advanced lung adenocarcinoma despite intact TGF‐β signaling. We identify E2A as a mutant KRAS–dependent mediator of resistance to TGF‐β–induced apoptosis. TGF‐β induces E2A via SMAD3 in mutant KRAS cells, and E2A silencing restores apoptosis and enhances radiation response in cell lines ...
Sergei Chuikov, Shiva Krishna Katkam, Zhefan Wang, Venkateshwar G. Keshamouni   +3 more
wiley   +1 more source

Acoustic Signal-Based Deep Learning Approach and Device for Detecting Interfacial Voids in Steel–Concrete Composite Structures

Advances in Civil Engineering
The reliable synergy between steel and concrete is an important evaluation criterion for the safety and long-term use of steel–concrete composite structures (SCCSs).
Wei Tian, Hang Yuan, Xinpeng You, Hehui Zheng, Bazhou Li, Chengming Peng   +5 more
doaj   +1 more source

The harbour

, 1996
Biblioteca de Educación del Ministerio de Educación, Cultura y Deporte; Calle San Agustín, 5 - 3 planta; 28014 Madrid; Tel.
Hooper, Meredith, Kent, Peter (il.)
openaire   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source