Results 41 to 50 of about 66,614 (249)

Comparing the paths of Hedgehog release in artificial and natural settings

FEBS Letters, EarlyView.
Hh morphogens require solubilization factors to overcome their tight association with the plasma membrane and signal to distant cells, but the precise functions of these factors are controversial. Here, we use published in vivo observations as the most relevant evidence to test their suggested functions and discuss contradictions and gaps between in ...
Janna Puschmann, Kay Grobe
wiley   +1 more source

Multiphysics Modeling of Volcanic Unrest at Mt. Ruapehu (New Zealand)

Geochemistry, Geophysics, Geosystems, 2022
Pre‐eruptive signals at the crater lake‐bearing Mt. Ruapehu (New Zealand) are either absent or hard to identify. Here, we report on geophysical anomalies arising from hydrothermal unrest (HTU) and magmatic unrest (MU) using multiphysics numerical ...
Fee Arens, Armando Coco, Joachim Gottsmann, James Hickey, Geoff Kilgour   +4 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

The study of thermal processes during grinding knives from hard-to-cut steels

Известия высших учебных заведений. Поволжский регион:Технические науки, 2023
Background. In modern mechanical engineering, knives made of hard-to-cut steels are widely used, the main advantage of which is increased heat resistance and wear resistance. The knives are subject to high demands on the geometric accuracy of surfaces
T.N. Ivanova, G.V. Kozlov, A.Yu. Muyzemnek   +2 more
doaj   +1 more source

Prediction of mining-induced seismicity and damage assessment of induced surface buildings in thick and hard key stratum working face: a case study of Liuhuanggou coal mine in China

Frontiers in Earth Science, 2023
Thick and hard key stratum working faces are characterized by frequent mine tremors and significant ground tremors during mining which seriously threaten the safety production of the mine.
Gaoang Wang, Sitao Zhu, Xiufeng Zhang, Yingyuan Wen, Zhijie Zhu, Quanjie Zhu, Liangfu Xie, Jiajie Li, Yi Tan, Tao Yang, Yuanyuan Pu, Chun Zhu, Chun Zhu   +12 more
doaj   +1 more source

Heterotropic regulation and negative homotropic cooperativity

FEBS Open Bio, EarlyView.
We identified a structural module common to some proteins that couple negative cooperativity with heterotropic regulation, two features that rarely coexist. These proteins are ring‐like and present an ordered asymmetry whereby noncontacting subunits are symmetric, and their tertiary structure differs from that of contacting subunits.
Veronica Morea, Francesco Angelucci, Federica Arnesano, Gianmarco Pascarella, Patrizio Di Micco, Andrea Bellelli   +5 more
wiley   +1 more source

Mechanical Properties of the Hard Sandstone Fracture Surface under Hydrochemical Corrosion

Journal of Engineering, 2019
To realize a quantitative expression of change laws of the fracture surface shear strength with hydrochemical damage and to obtain optimal weakening effect of solution on the fracture surface strength, hard roof sandstone specimens containing hydraulic ...
Bin-wei Xia, Ming-xiang Xu, Chao Pan
doaj   +1 more source

Rainfall runoff features of permeable sidewalk pavement

Journal of Water and Climate Change, 2021
In urban areas, the buildings and pavements make it hard for rainwater to infiltrate into the ground. The hardened underlaying sub-crust has increased the total rainfall runoff, pushing up the peak flood flow.
Liyuan Qiu, Yu Zhang, Sheng Zhang, Jingwei Zhao, Tengfei Wang, Qiang Wang   +5 more
doaj   +1 more source

Genetic dissection of human ABCE1 in yeast reveals separable requirements for ribosome recycling and suppression of aberrant reinitiation

FEBS Open Bio, EarlyView.
Human ABCE1 cannot functionally replace its yeast ortholog. Yeast–human chimera analysis identified NBD1 as a major interspecies barrier. Genetic screening yielded hABCE1 revertants that rescue yeast viability but fail to suppress aberrant translation reinitiation in the 3′ UTR.
Eriko Nakata, Yuxin Li, Kei Endo, Koichi Ito   +3 more
wiley   +1 more source

The future of underground spatial planning and the resulting potential risks from the point of view of mining subsidence engineering

International Journal of Mining Science and Technology, 2020
The topic of ground movements in Germany has been studied extensively in the past, especially in the field of active mines. The active hard coal mines in Germany were finally shut down in 2018 and lignite mining is expected to take place only until 2038.
Carolina Brücker, Axel Preuße
doaj   +1 more source