Results 71 to 80 of about 5,135,844 (257)

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

open access: yesFEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg   +14 more
wiley   +1 more source

Modeling the effects of initial grain size, martensitic transformation induced dynamic grain refinement, phases, and texture on strength of a high entropy alloy using crystal plasticity

open access: yesJournal of Materials Research and Technology
Microstructurally flexible high entropy alloys (HEAs) can be tailored for strength via dual-phase strengthening mechanisms, which originate from the strain-induced phase transformation microstructural phenomena.
Zhangxi Feng   +3 more
doaj   +1 more source

Hybrid Reconstruction Approach for Polychromatic Computed Tomography in Highly Limited-Data Scenarios

open access: yesSensors
Conventional strategies aimed at mitigating beam-hardening artifacts in computed tomography (CT) can be categorized into two main approaches: (1) postprocessing following conventional reconstruction and (2) iterative reconstruction incorporating a beam ...
Alessandro Piol   +5 more
doaj   +1 more source

An approach to develop printable strain hardening cementitious composites

open access: yesMaterials & Design, 2019
New additive manufacturing methods for cementitious materials hold a high potential to increase automation in the construction industry. However, these methods require new materials to be developed that meet performance requirements related to specific ...
Stefan Chaves Figueiredo   +8 more
doaj   +1 more source

Work Softening And Annealing Hardening Of Deformed Nanocrystalline Nickel

open access: yes, 2008
We reported that work softening takes place during room-temperature rolling of nanocrystalline Ni at an equivalent strain of around 0.30. The work softening corresponds to a strain-induced phase transformation from a face-centered cubic (fcc) to a body ...
Zhang XY   +4 more
core   +1 more source

Overview of ionizing radiation effects in image sensors fabricated in a deep-submicrometer CMOS imaging technology [PDF]

open access: yes, 2009
An overview of ionizing radiation effects in imagers manufactured in a 0.18-μm CMOS image sensor technology is presented. Fourteen types of image sensors are characterized and irradiated by a 60Co source up to 5 kGy.
Goiffon, Vincent   +2 more
core   +1 more source

Structure‐forward targeting of claudins with synthetic binders

open access: yesFEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Distribution system resilience improvement against hurricanes: optimal line hardening according to reconfiguration potentials

open access: yesThe Journal of Engineering
In recent years, there has been a notable increase in the frequency and intensity of natural disasters related to global warming. Large‐scale blackouts caused by natural disasters demonstrate the extreme vulnerability of power systems to these ...
Navid Talaei Pashiri   +2 more
doaj   +1 more source

Application of newly proposed hardening laws for structural steel rods

open access: yesVietnam Journal of Mechanics
In civil engineering, distinct mechanical properties and behaviors of structural steel rods necessitate a novel approach to material modeling. This study extends the application of recently proposed strain-hardening laws, originally developed for ...
Van Nam Nguyen   +2 more
doaj   +1 more source

Engineering peptides into antibodies—opportunities and strategies for therapeutic innovation

open access: yesFEBS Letters, EarlyView.
Peptides and antibodies occupy complementary therapeutic niches. Peptides recognize difficult targets in a compact format, while antibodies add specificity, long half‐life, and effector functions. This review examines strategies that merge both modalities—peptide grafting into loops, terminal and Fc fusions, and bioconjugation—highlighting how ...
Jinling Wang   +2 more
wiley   +1 more source

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