Results 61 to 70 of about 909,127 (312)

#Online harms or benefits? An ethnographic analysis of the positives and negatives of peer-support around self-harm on social media.

Journal of Child Psychology and Psychiatry and Allied Disciplines, 2020
BACKGROUND There is emerging evidence of the potentially detrimental impact of social media on young people's mental health. Against this background, online self-harm content has been a recent focus of concern across academia, policy and the media.
Anna C Lavis, Rachel Winter
semanticscholar   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Come back when you’re infected: pharmacy access to sterile syringes in an Arizona Secret Shopper Study, 2023

Harm Reduction Journal
Background Pharmacies are critical healthcare partners in community efforts to eliminate bloodborne illnesses. Pharmacy sale of sterile syringes is central to this effort.
Danielle M. Russell, Beth E. Meyerson, Arlene N. Mahoney, Irene Garnett, Chris Ferrell, Kylee Newgass, Jon D. Agley, Richard A. Crosby, Keith G. Bentele, Nina Vadiei, David Frank, Linnea B. Linde-Krieger   +11 more
doaj   +1 more source

Integration of a community-based harm reduction program into a safety net hospital: a qualitative study

Harm Reduction Journal, 2022
Background Community-based harm reduction programs reduce morbidity and mortality associated with drug use. While hospital-based inpatient addiction consult services can also improve outcomes for patients using drugs, inpatient clinical care is often ...
Ghulam Karim Khan, Leah Harvey, Samantha Johnson, P. Long, S. Kimmel, C. Pierre, M. Drainoni   +6 more
semanticscholar   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Neo-colonialism and financing for the war on drugs: a review of current policy and recommendations for countries in the global north

Harm Reduction Journal
Globally, punitive drug control upholds racist and colonial structures. Marginalised and racialised communities, including Indigenous peoples, are disproportionately targeted and affected by punitive drug policy in law enforcement, judicial and carceral ...
Colleen Daniels, Naomi Burke-Shyne, Catherine Cook, Anoushka Beattie   +3 more
doaj   +1 more source

The Bronze Age of drug checking: barriers and facilitators to implementing advanced drug checking amidst police violence and COVID-19

Harm Reduction Journal, 2022
Objectives Unpredictable fluctuations in the illicit drug market increase overdose risk. Drug checking, or the use of technology to provide insight into the contents of illicit drug products, is an overdose prevention strategy with an emerging evidence ...
Jennifer J. Carroll, Sarah Mackin, Clare Schmidt, Michelle McKenzie, Traci C. Green   +4 more
doaj   +1 more source

Research on the Harm of Food-derived Advanced Glycation End Products to Human Health

Shipin gongye ke-ji, 2022
Food-derived advanced glycation end products (AGEs) are irreversible covalent compounds formed by Maillard reactions of reducing sugars with proteins, nucleic acids and lipids under non-enzymatic conditions.
Pin GONG, Shuya PEI, Yewen HAN, Wenjuan YANG, Xiangna CHANG, Fuxin CHEN   +5 more
doaj   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source