Results 71 to 80 of about 824,404 (357)

Parental Licensing as Harm Reduction [PDF]

Health Care Analysis, 2020
AbstractIn this paper, I will argue that some prominent objections to parental licensing rely on dubious claims about the existence of a very stringent, if not indefeasible, right to parent, which would be violated by licensing. I claim that attaching such stringency to the right only makes sense if we make a number of idealising assumptions. Otherwise,
openaire   +4 more sources

A working model for cytoplasmic assembly of H/ACA snoRNPs

FEBS Letters, EarlyView.
Dyskerin is the component of nuclear H/ACA ribonucleoproteins (RNPs) endowed with pseudouridine synthase catalytic activity. Two isoforms of human dyskerin have been characterized: the abundant Iso1, mainly nuclear, and the shorter Iso3, mainly cytoplasmic but occasionally imported into nuclei.
Alberto Angrisani, Maria Furia
wiley   +1 more source

Review of local alcohol harm reduction strategies in Cheshire and Merseyside [PDF]

, 2008
This report reviews local alcohol strategies in Cheshire and Merseyside.ChaMPs Public Health ...
Bridgman, Stephen, Cawley, Lucinda, Mann, Frances, Thurston, Miranda   +3 more
core  

Harm reduction as a strategy for supporting people who self-harm on mental health wards : the views and experiences of practitioners [PDF]

, 2017
BACKGROUND: Harm reduction has had positive outcomes for people using sexual health and substance misuse services. Clinical guidance recommends these approaches may be appropriately adopted by mental health practitioners when managing some people who ...
James, Karen, Moran, Paul, Samuels, Isaac, Stewart, Duncan   +3 more
core   +3 more sources

ERS and tobacco harm reduction [PDF]

European Respiratory Journal, 2019
ERS supports the World Health Organization9s Framework Convention on Tobacco Control, which also provides regulation to novel products, and cannot recommend tobacco harm reduction as a population-based strategyhttp://bit.ly ...
Pisinger, C, Dagli, E, Filippidis, FT, Hedman, L, Janson, C, Loukides, S, Ravara, S, Saraiva, I, Vestbo, J, ERS Tobacco Control Committee, on behalf of the ERS   +10 more
openaire   +5 more sources

C9orf72 ALS‐causing mutations lead to mislocalization and aggregation of nucleoporin Nup107 into stress granules

FEBS Letters, EarlyView.
Mutations in the C9orf72 gene represent the most common genetic cause of amyotrophic lateral sclerosis (ALS), a fatal neurodegenerative disease. Using patient‐derived neurons and C. elegans models, we find that the nucleoporin Nup107 is dysregulated in C9orf72‐associated ALS. Conversely, reducing Nup107 levels mitigates disease‐related changes.
Saygın Bilican, Yara Nabawi, William Hongyu Zhang, Dunja Petrovic, Markus Wehrmann, Sara Muñoz‐García, Seda Koyuncu, David Vilchez   +7 more
wiley   +1 more source

‘This is PEEP’ participatory qualitative study: learning from a provincial consultation and advisory group of people with lived and living experience of substance use in British Columbia, Canada

BMJ Open
Objectives To summarise PEEP’s (Professionals for Ethical Engagement of Peers—a group of consultants with lived and living experience of substance use) outputs and gain insights into PEEP’s impact and suggestions for the future.Design Included an ...
Jane A Buxton, Kurt Lock, Charlene Burmeister, Kerolos Daowd, Jessica Lamb, Jenny McDougall, Amirnima Danaei, Paul Choisil, Elizabeth Haywood, Iesha Henderson, Kali Sedgemore   +10 more
doaj   +1 more source

Mesenchymal Stem Cell–Derived Extracellular Vesicles: New Soldiers in the War on Immune-Mediated Diseases

Cell Transplantation, 2023
Inflammatory diseases are a group of debilitating disorders with varying degrees of long-lasting functional impairment of targeted system. New therapeutic agents that will attenuate on-going inflammation and, at the same time, promote regeneration of ...
Zeljko Ivosevic, Biljana Ljujic, Dragica Pavlovic, Vesna Matovic, Marina Gazdic Jankovic   +4 more
doaj   +1 more source

Tipping the Balance: Why Legal Services Are Essential to Health Care for Drug Users in Ukraine [PDF]

, 2008
Examines the need to integrate legal support for drug users with harm reduction programs to effectively stem the spread of HIV/AIDS. Discusses approaches, legal problems, and recommendations for government policy and for nongovernmental ...
Carey, Corinne, Tolopilo, Andrey
core  

From lactation to malignancy: A comparison between healthy and cancerous breast gland at single‐cell resolution reveals new issues for tumorigenesis

FEBS Letters, EarlyView.
Single‐cell RNA sequencing reveals an opposite role of SLPI in basal tumors based on metastatic spread, along with shared activation of specific regulons in cancer cells and mature luminal lactocytes, as well as downregulation of MALAT1 and NEAT1 in the latter.
Pietro Ancona, Carlo M. Bergamini, Carlo Ferrari, Stefano Volinia, Nicoletta Bianchi   +4 more
wiley   +1 more source