Results 71 to 80 of about 850,081 (293)

Tipping the Balance: Why Legal Services Are Essential to Health Care for Drug Users in Ukraine [PDF]

, 2008
Examines the need to integrate legal support for drug users with harm reduction programs to effectively stem the spread of HIV/AIDS. Discusses approaches, legal problems, and recommendations for government policy and for nongovernmental ...
Carey, Corinne, Tolopilo, Andrey
core  

Revealing the structure of land plant photosystem II: the journey from negative‐stain EM to cryo‐EM

FEBS Letters, EarlyView.
Advances in cryo‐EM have revealed the detailed structure of Photosystem II, a key protein complex driving photosynthesis. This review traces the journey from early low‐resolution images to high‐resolution models, highlighting how these discoveries deepen our understanding of light harvesting and energy conversion in plants.
Roman Kouřil
wiley   +1 more source

‘This is PEEP’ participatory qualitative study: learning from a provincial consultation and advisory group of people with lived and living experience of substance use in British Columbia, Canada

BMJ Open
Objectives To summarise PEEP’s (Professionals for Ethical Engagement of Peers—a group of consultants with lived and living experience of substance use) outputs and gain insights into PEEP’s impact and suggestions for the future.Design Included an ...
Jane A Buxton, Kurt Lock, Charlene Burmeister, Kerolos Daowd, Jessica Lamb, Jenny McDougall, Amirnima Danaei, Paul Choisil, Elizabeth Haywood, Iesha Henderson, Kali Sedgemore   +10 more
doaj   +1 more source

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Mesenchymal Stem Cell–Derived Extracellular Vesicles: New Soldiers in the War on Immune-Mediated Diseases

Cell Transplantation, 2023
Inflammatory diseases are a group of debilitating disorders with varying degrees of long-lasting functional impairment of targeted system. New therapeutic agents that will attenuate on-going inflammation and, at the same time, promote regeneration of ...
Zeljko Ivosevic, Biljana Ljujic, Dragica Pavlovic, Vesna Matovic, Marina Gazdic Jankovic   +4 more
doaj   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

FEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo, Catherine S. Palmer, Jacqueline M. Kimmey   +2 more
wiley   +1 more source

Measuring sustainability of opioid agonist therapy programs in the context of transition from Global Fund support

Harm Reduction Journal
Background Programmatic and financial sustainability of health responses dependent on donor funding has risen as a major concern. In the HIV field in particular, it generated a number of instruments and assessments on sustainability and processes related
Raminta Stuikyte, Ivan Varentsov, Catherine Cook, Sergii Dvoriak   +3 more
doaj   +1 more source

Can the Heinrich ratio be used to predict harm from medication errors? [PDF]

, 2006
The purpose of this study was to establish whether, for medication errors, there exists a fixed Heinrich ratio between the number of incidents which did not result in harm, the number that caused minor harm, and the number that caused serious harm.
Barber, N, Franklin, BD, Gallivan, S, Taxis, K   +3 more
core  

Insufficient access to harm reduction measures in prisons in 5 countries (PRIDE Europe): a shared European public health concern [PDF]

, 2015
Background: Prisoners constitute a high-risk population, particularly for infectious diseases. The aim of this study was to estimate the level of infectious risk in the prisons of five different European countries by measuring to what extent the prison ...
Brentari, Cinzia, Holm, Karina, Jauffret-Roustide, Marie, Kolind, Torsten, Lion, Caroline, M Carrieri, Patrizia, Maguet, Olivier, Michel, Laurent, Moser, Andrea, Nava, Felice, Schiltz, Julie, Stöver, Heino, Van Malderen, Sara, Vanderplasschen, Wouter, Weltzien, Nadja   +14 more
core   +5 more sources

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source