A plain language summary of the BASIS study looking at people living with severe hemophilia A or B with inhibitors and being treated with marstacimab. [PDF]
Matino D +8 more
europepmc +1 more source
AI‐Enabled Precision Dosing in Pediatrics: Enhancing Model‐Informed Decision Making
Ensuring safe and effective pharmacotherapy for children remains a central challenge in clinical pharmacology, yet rapid advances in AI have not translated into clinical practice. This Perspective highlights how AI‐enabled approaches can enhance model‐informed decision making for precision dosing.
Kei Irie, Tomoyuki Mizuno
wiley +1 more source
Integrating senotherapeutics into transplantation: liver reconditioning in an aging donor pool. [PDF]
Buch ML +5 more
europepmc +1 more source
A Fast and Highly Stable Aqueous Calcium‐Ion Battery for Sustainable Energy Storage
Aqueous batteries provide a low‐cost, safer alternative to lithium‐ion batteries, but their viability is often limited by rapid electrode degradation. This study shows that replacing K+ with divalent Ca2+ ions in the electrolyte significantly boosts the stability of both copper hexacyanoferrate cathodes and polyimide anodes, enabling fast‐charging ...
Raphael L. Streng +4 more
wiley +1 more source
Programmed death 1 antibody drug conjugates (PD 1 ADCs): Innovations in overcoming resistance and enhancing immune mediated antitumor activity. [PDF]
Tian Z.
europepmc +1 more source
The addition of Na2CO3 or K2CO3 to sewage sludge prior to combustion leads to the production of ashes containing phosphate in the form of buchwaldite‐like phases (Ca(Na/K)PO4). Compared to conventional sewage sludge mono‐ashes, such Na‐ or K‐ashes show greatly increased P‐solubilities and proved to be potent P‐fertiliser materials in greenhouse ...
Lorenz Bier‐Schorr +4 more
wiley +1 more source
Risks of AI scientists: prioritizing safeguarding over autonomy. [PDF]
Tang X +13 more
europepmc +1 more source
RORγt‐APCs: The New Masters of Oral Tolerance
ABSTRACT Oral tolerance is defined by the hypo‐responsiveness of our body to fed antigens, and its failure can lead to immune‐mediated diseases, such as allergy, chronic inflammation and autoimmune diseases. Decades of research have demonstrated that antigen‐presenting cells (APCs) promote oral tolerance by inducing regulatory T cells (Tregs) and/or ...
Thierry Gauthier, WanJun Chen
wiley +1 more source
Lipid balance and chemoresistance in cancer cells. [PDF]
Kanemaru K, Nakamura Y.
europepmc +1 more source
This review summarizes the synergistic effects of mixed impurities on ammonia‐selective catalytic reduction (NH3‐SCR) catalysts, including the poisoning mechanism of the catalyst caused by mixed impurities, the antagonistic effects between the impurities, and the research on the anti‐poisoning strategies for the catalyst in recent years.
Hongyan Xue +3 more
wiley +1 more source

