Dapagliflozin alleviates high‐fat‐induced obesity cardiomyopathy by inhibiting ferroptosis
Abstract Aim: Dapagliflozin (Dapa) is a novel hypoglycaemic agent with multiple cardiovascular protective effects, and it is widely used in treatment of heart failure patients, but whether it can improve obese phenotype of heart failure and its mechanism is still unclear.
Di Chen +7 more
wiley +1 more source
The deliberate use of biological and chemical agents to cause harm: public health response.
openaire +1 more source
Moving Beyond the Hype in Extracellular Vesicle Therapy. [PDF]
Marbán E.
europepmc +1 more source
Retro‐Hetero‐Michael Addition Strategies in Organic Synthesis
In this review, synthetic approaches to carbo‐ and heterocyclic compounds, including natural products, published in the last 15 years (2011–2025) which have either relied upon or included a retro‐hetero‐Michael addition step at any stage are discussed.
Dina Scarpi, Ernesto G. Occhiato
wiley +1 more source
Commercial and on-farm microbial bioinputs production systems: challenges, opportunities and current Brazilian regulatory framework. [PDF]
Xavier VL +2 more
europepmc +1 more source
Risk assessment using IEUBK model for the Naica mine tailings
Abstract Mexico has a long history of mineral extraction, during which limited environmental regulations allowed the accumulation of toxic waste near communities, primarily in rural or undeveloped areas. Some of these toxic substances, such as lead, pose significant risks to vulnerable populations, particularly children aged 0 to 7 years.
A. Contreras‐Guardiola +4 more
wiley +1 more source
Recent advancements of wastewater treatment by photocatalysis: A comprehensive review. [PDF]
Swamy KR +4 more
europepmc +1 more source
Seizure forecasting: The long and winding road to clinical translation
Abstract Seizure forecasting has progressed from theoretical aspiration to a rapidly advancing research domain, yet clinical translation remains limited. Over the past decades, advances in algorithm development, chronic electroencephalography (EEG), wearable sensors, and the characterization of seizure cycles have demonstrated that seizure risk is not ...
Philippa J. Karoly +7 more
wiley +1 more source
Novel Tricyclic Compounds as 5‑HT2A Receptor Agonists for Treating Depression, Anxiety, Substance Abuse, and Headaches. [PDF]
Sabnis RW, Sabnis AR.
europepmc +1 more source
Inherited metabolic epilepsies–established diseases, new approaches
Abstract Inherited metabolic epilepsies (IMEs) represent the inherited metabolic disorders (IMDs) in which epilepsy is a prevailing component, often determining other neurodevelopmental outcomes associated with the disorder. The different metabolic pathways affected by individual IMEs are the basis of their rarity and heterogeneity.
Itay Tokatly Latzer, Phillip L. Pearl
wiley +1 more source

