Results 21 to 30 of about 3,677 (212)
Awareness of Adolescents Students about the Harmful Effects of Smoking at Al-Qaswa Schools in Al-Madinah Al-Munawara [PDF]
Helwan International Journal for Nursing Research and PracticeAdolescents are vulnerable to starting smoking and becoming addicted to nicotine. Aim: This study aimed to assess awareness of adolescent students about the harmful effects of smoking at Al-Qaswa schools in Al-Madinah Al-Munawara.
Abeer Alhazmi
doaj +1 more source
How affordances and social norms shape the discussion of harmful social media challenges on reddit
Human Factors in Healthcare, 2023 Social media challenges are activities performed by an individual or a group and uploaded to social media platforms to achieve a specific goal. We sought to understand how harmful social media challenges are portrayed on Reddit.
Jinkyung Park +6 more
doaj +1 more source
Designing the Swedish Crime Harm Index: an Evidence-Based Strategy [PDF]
Cambridge Journal of Evidence-Based Policing, 2020 Abstract Research Question Which method for deriving a Crime Harm Index (Policing 10:171–183, 2016) for Sweden from criminal justice sources offers the best evidence for providing a sensitive indicator of differences in harm levels across offence categories?
Kärrholm, Fredrik +2 more
openaire +3 more sources
Designing for Digital Wellbeing: From Theory to Practice a Scoping Review
Human Behavior and Emerging Technologies, 2023 In a world that is highly dependent on digital connectivity, technology use is becoming unavoidable, intense, and possibly harmful. The pervasiveness of technology which has been in tandem with the increasing number of reported cases of harmful usage ...
Reem S. Al-Mansoori +2 more
doaj +1 more source
Reciprocal control of viral infection and phosphoinositide dynamics
FEBS Letters, EarlyView.Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
An in vivo strategy to counteract post-administration anticoagulant activity of azido-Warfarin
Nature Communications, 2017 The interaction of long circulating drugs with biological molecules might trigger harmful side effects. Here, the authors design an anticoagulant compound that can be deactivatedin vivo using click chemistry, paving the way to the design of drugs with ...
Sylvain Ursuegui +3 more
doaj +1 more source
Gut microbiome and aging—A dynamic interplay of microbes, metabolites, and the immune system
FEBS Letters, EarlyView.Age‐dependent shifts in microbial communities engender shifts in microbial metabolite profiles. These in turn drive shifts in barrier surface permeability of the gut and brain and induce immune activation. When paired with preexisting age‐related chronic inflammation this increases the risk of neuroinflammation and neurodegenerative diseases.
Aaron Mehl, Eran Blacher
wiley +1 more source
Harmful state aid – attempt to designate methods of identification [PDF]
Oeconomia Copernicana, 2011 Implementing the concept of sustainable development is one of the major challenges facing the modern world. One of the instruments creating sustainable development might be state aid. State aid has an impact not only on the economic sphere but also the environmental and social.
openaire +2 more sources
FEBS Letters, EarlyView.Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley +1 more source
Reconstructing enzyme evolution by protein engineering
FEBS Letters, EarlyView.Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler +2 more
wiley +1 more source