Results 51 to 60 of about 9,815,687 (260)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Surfing for Inspiration: digital inspirational material in design practice [PDF]

, 2018
Over the last decade, many new opportunities have emerged to support creativity and problem-solving in design by finding inspirational materials via the Internet.
Laszlo, Magda, Koch, Janin, Andrés LUCERO, Lucero, Andrés, Antti OULASVIRTA, Oulasvirta, Antti, Magda LÁSZLÓ, Lucero Vera, Andres, Janin KOCH   +8 more
core   +1 more source

Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer

Molecular Oncology, EarlyView.
Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim, Maryam Aslam, Elouise Torruella, Alphons Sony, Asif Rahman, Simira Smith, Columba de la Parra, Moira Sauane   +7 more
wiley   +1 more source

Design, synthesis, and biological evaluation of phenyl-oxime derivatives as selective algicides for harmful algae

Chemical and Biological Technologies in Agriculture
Background Harmful algal blooms (HABs) threaten water quality and aquatic life, yet many chemical controls raise concerns about non-target toxicity.
Yeo Jin Kim, Jun Young Lee, Bong Gyu Choi, Jin-Seog Kim, Hasoo Seong, Chul Min Park, Seok Ki Min, Hyun-Suk Yeom, Joon-Ho Lee   +8 more
doaj   +1 more source

Evaluating the involvement of autolysosomes in the nuclear translocation of fluorescent proteins

FEBS Open Bio, EarlyView.
Endogenously expressed fluorescent proteins can be degraded by autophagy and transported to cell nuclei via the nuclear pore complex. But in some cell lines, for example, HeLa cells which are positive for immunoreactivity of a receptor ligand, such as UCN I, in cell nuclei, fusion of autolysosome with the nuclear envelope is involved in the nuclear ...
Keiichi Ikeda
wiley   +1 more source

Material and Process Design for Lightweight Structures

Metals, 2019
The ever-rising demand for increased fuel efficiency and a reduction in the harmful emission of greenhouse gases associated with energy generation and transportation has led, in recent years, to a resurgence of interest in light materials and new ...
Talal Al-Samman
doaj   +1 more source

High-Efficiency Simulation Framework to Analyze the Impact of Exhaust Air from COVID-19 Temporary Hospitals and its Typical Applications

Applied Sciences, 2020
The outbreak of COVID-19 resulted in severe pressure on the existing medical infrastructure in China. Several Chinese cities began to construct temporary hospitals for the centralized treatment of COVID-19 patients.
Donglian Gu, Zhe Zheng, Pengju Zhao, Linlin Xie, Zhen Xu, Xinzheng Lu   +5 more
doaj   +1 more source

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Harmful cultural practices during perinatal period and associated factors among women of childbearing age in Southern Ethiopia: Community based cross-sectional study.

PLoS ONE, 2021
IntroductionAlthough the maternal mortality ratio has decreased by 38% in the last decade, 810 women die from preventable causes related to pregnancy and childbirth every day, and two-thirds of maternal deaths occur in Sub-Saharan Africa alone. The lives
Haimanot Abebe, Girma Alemayehu Beyene, Berhanu Semra Mulat   +2 more
doaj   +1 more source

Avidin is evolutionarily conserved in fish but dispensable for development and resistance against Streptococcus agalactiae in zebrafish

FEBS Open Bio, EarlyView.
The presence of biotin‐binding avidin proteins in fish and their biological significance are poorly characterized. We cataloged fish avidins and demonstrate that they are widely present and evolutionarily conserved. We created avd knockout zebrafish and show that zebavidin is dispensable for development and that resistance of avd knockout embryos in ...
Anni K. Saralahti, Markus J. T. Ojanen, Mataleena Parikka, Otto Kauko, Mika Rämet, Vesa P. Hytönen   +5 more
wiley   +1 more source