Results 171 to 180 of about 7,262 (218)
Colorectal cancer cell line-derived organoid model with stem cell properties captures the regrowing state of residual cancer cells after neoadjuvant chemotherapy. [PDF]
Nakano K +21 more
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2.2Å ブンカイノウ デノ ヒト ユライ モノアミン サンカ コウソA ノ ケッショウ コウゾウ ト ソノ マクカンツウ ヘリックス ノ キノウテキ ヤクワリ [PDF]
Son, Seyoung +2 more
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2022
Basic research project with rodents. Rodents were administerred DMT and/or harmine and to investigate effects on 5HT2A receptor occupancy of DMT, changes in FDG uptake and brain concentrations of DMT, harmine and their metabolites. This work is published at Frontiers in Pharmacology (DOI: 10.3389/fphar.2023.1140656).
Scheidegger, Milan +2 more
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Basic research project with rodents. Rodents were administerred DMT and/or harmine and to investigate effects on 5HT2A receptor occupancy of DMT, changes in FDG uptake and brain concentrations of DMT, harmine and their metabolites. This work is published at Frontiers in Pharmacology (DOI: 10.3389/fphar.2023.1140656).
Scheidegger, Milan +2 more
openaire +1 more source
Mechanisms of tremor induction by harmine
European Journal of Pharmacology, 1974Abstract Various agents known to modify cerebral serotoninergic, dopaminergic and cholinergic function were used to investigate the possible relationship between these transmitter systems and the induction and modulation of harmine tremor. The results indicate a non-involvement of cerebral cholinergic function and a possible involvement of cerebral ...
D M, Kelly, R J, Naylor
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Harmine Action in Rats with Lymphostatic Encephalopathy
Pharmacology, 1977In rats with lymphostatic encephalopathy the duration of harmine tremor was lengthened, and the brain concentrations of harmine decreased more slowly than in sham-operated controls. The tremor began simultaneously in both rat groups at coinciding brain concentrations of harmine.
G, Back, G, Seidel
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Untersuchungen zur Biosynthese des Harmins
Archiv der Pharmazie, 1968AbstractMit Hilfe markierter Vorstufen wurde die Biosynthese des Harmins (I) in Peganum harmala untersucht. Durch Fütterung von Tryptophan‐(β‐14C‐15Nβ) konnte gezeigt werden, das die Seitenkette mit Ausnahme der Carboxylgruppe spezifisch in das β‐Carbolin‐System eingebaut wird. Das gleiche Ergebnis wurde mit Tryptamin‐(β‐14C‐15N) erzielt.
K. Stolle, D. Gröger
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DNA binding properties of 9-substituted harmine derivatives
Biochemical and Biophysical Research Communications, 2005The beta-carboline alkaloids have been characterized as a group of potential antitumor agents. The underlying mechanisms of harmine and its derivatives were investigated by DNA binding assay and Topoisomerase (Topo) inhibition assay. Meanwhile, the DNA photocleavage potential of these compounds and their cytotoxicity were also examined by DNA ...
Rihui, Cao +7 more
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THE HARMIN RESERVOIR (IRAQ) COASTAL DYNAMICS
Geomorphology RAS, 2016The Hamrin reservoir, located on the Diyala River (left tributary of the Tiger River), differ for its unusual shape, large surface area and small depth, a significant level fl uctuations in the long-term dynamics and great depth of drawdown, and intense siltation.
D. A. SUBETTO +3 more
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