Results 51 to 60 of about 1,110,187 (308)

Demonstration of Improving the Performance of a Fibre Optic Displacement Sensor Using the Optical Harmonic Vernier Effect by Cascading Tapered Optical Single-Mode Fibres

open access: yesIEEE Photonics Journal, 2023
An experimental demonstration for generating harmonics in the optical Vernier effect (OVE) by cascading tapered single-mode fibres (SMF28) is presented. The tapered optical fibres conformed to a pair of in-series Mach-Zehnder fibre interferometers (MZFI),
L. Guillen-Ruiz   +5 more
doaj   +1 more source

Leveraging multiple data types for improved compound-kinase bioactivity prediction

open access: yesNature Communications
Machine learning provides efficient ways to map compound-kinase interactions. However, diverse bioactivity data types, including single-dose and multi-dose-response assay results, present challenges.
Ryan Theisen   +4 more
doaj   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Coupling microstrip line bandpass filter applied to hybrid frequency synthesizers

open access: yesDianzi Jishu Yingyong, 2018
This paper designs a parallel coupled microstrip bandpass filter at the ends of the hybrid frequency synthesizer of PLL+DDS mixing in the outside of the feedback loop systems. This filter is used to suppress the frequency synthesizer′s spurs and harmonic
Chai Xiaorong   +2 more
doaj   +1 more source

Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer

open access: yesMolecular Oncology, EarlyView.
Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte   +10 more
wiley   +1 more source

On harmonic and asymptotically harmonic homogeneous spaces [PDF]

open access: yesGAFA Geometric And Functional Analysis, 2006
We classify noncompact homogeneous spaces which are Einstein and asymptotically harmonic. This completes the classification of Riemannian harmonic spaces in the homogeneous case: Any simply connected homogeneous harmonic space is flat, or rank-one symmetric, or a nonsymmetric Damek-Ricci space. Independently, Y.
openaire   +3 more sources

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

open access: yesFEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi   +2 more
wiley   +1 more source

Harmonic Vector Error Analysis Based on Lagrange Interpolation

open access: yesIEEE Access, 2021
With the development of smart substations and the promotion of 61850 standards, sampling values based on IEC61850-9-2 have become an important part of smart substation construction.
Zhaoyun Zhang, Qitong Wang, Zhi Zhang
doaj   +1 more source

The harmonic polytope

open access: yesSelecta Mathematica, 2021
We study the harmonic polytope, which arose in Ardila, Denham, and Huh's work on the Lagrangian geometry of matroids. We describe its combinatorial structure, showing that it is a $(2n-2)$-dimensional polytope with $(n!)^2(1+\frac12+\cdots+\frac1n)$ vertices and $3^n-3$ facets.
Federico Ardila   +2 more
openaire   +3 more sources

The MSA Atrophy Index (MSA‐AI): An Imaging Marker for Diagnosis and Clinical Progression in Multiple System Atrophy

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Reliable biomarkers are essential for tracking disease progression and advancing treatments for multiple system atrophy (MSA). In this study, we propose the MSA Atrophy Index (MSA‐AI), a novel composite volumetric measure to distinguish MSA from related disorders and monitor disease progression. Methods Seventeen participants with an
Paula Trujillo   +11 more
wiley   +1 more source

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