Results 51 to 60 of about 1,125,521 (310)
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
Harmonics and Reduction of Energy Consumption in Lighting Systems by Using LED Lamps
Energies, 2018 This paper proposes the study and analysis of harmonics, energy consumption and power quality of light emitting diode (LED) lamps equipped in building lighting systems.
Natthanon Phannil +2 more
doaj +1 more source
Relating harmonic and projective descriptions of N=2 nonlinear sigma models
, 2013 Recent papers have established the relationship between projective superspace and a complexified version of harmonic superspace. We extend this construction to the case of general nonlinear sigma models in both frameworks.
A Galperin +39 more
core +1 more source
Molecular Oncology, EarlyView.Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié +16 more
wiley +1 more source
Dual-Frequency Piezoelectric Transducers for Contrast Enhanced Ultrasound Imaging
Sensors, 2014 For many years, ultrasound has provided clinicians with an affordable and effective imaging tool for applications ranging from cardiology to obstetrics.
K. Heath Martin +7 more
doaj +1 more source
Molecular Oncology, EarlyView.This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad +17 more
wiley +1 more source
Boundary singularities of N -harmonic functions [PDF]
, 2006 We construct N-harmonic functions in a domain with one isolated singularity on the boundary of the domain. By using solutions of the spherical p-harmonic spectral problem, we give an inductive method to produce a large variety of separable p-harmonic ...
Borghol, Rouba, Veron, Laurent
core +3 more sources
Aggressive prostate cancer is associated with pericyte dysfunction
Molecular Oncology, EarlyView.Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero +11 more
wiley +1 more source
Molecular Oncology, EarlyView.Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra +10 more
wiley +1 more source
Some explicit constructions of Dirac-harmonic maps
, 2009 We construct explicit examples of Dirac-harmonic maps $(\phi, \psi)$ between Riemannian manifolds $(M,g)$ and $(N,g')$ which are non-trivial in the sense that $\phi$ is not harmonic. When $\dim M=2$, we also produce examples where $\phi$ is harmonic, but
Biran +26 more
core +1 more source