Results 51 to 60 of about 1,109,117 (311)
FEBS Letters, EarlyView.In this work, we reveal how different enzyme binding configurations influence the fluorescence decay of NAD(P)H in live cells using time‐resolved anisotropy imaging and fluorescence lifetime imaging microscopy (FLIM). Mathematical modelling shows that the redox states of the NAD and NADP pools govern these configurations, shaping their fluorescence ...
Thomas S. Blacker +8 more
wiley +1 more source
Dual-Frequency Piezoelectric Transducers for Contrast Enhanced Ultrasound Imaging
Sensors, 2014 For many years, ultrasound has provided clinicians with an affordable and effective imaging tool for applications ranging from cardiology to obstetrics.
K. Heath Martin +7 more
doaj +1 more source
Relating harmonic and projective descriptions of N=2 nonlinear sigma models
, 2013 Recent papers have established the relationship between projective superspace and a complexified version of harmonic superspace. We extend this construction to the case of general nonlinear sigma models in both frameworks.
A Galperin +39 more
core +1 more source
Molecular Oncology, EarlyView.We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau +11 more
wiley +1 more source
Boundary singularities of N -harmonic functions [PDF]
, 2006 We construct N-harmonic functions in a domain with one isolated singularity on the boundary of the domain. By using solutions of the spherical p-harmonic spectral problem, we give an inductive method to produce a large variety of separable p-harmonic ...
Borghol, Rouba, Veron, Laurent
core +3 more sources
Systematic profiling of cancer‐fibroblast interactions reveals drug combinations in ovarian cancer
Molecular Oncology, EarlyView.Fibroblasts, cells in the tumor environment, support ovarian cancer cell growth and alter morphology and drug response. We used fibroblast and cancer cell co‐culture models to test 528 drugs and discovered new drugs for combination treatment. We showed that adding Vorinostat or Birinapant to standard chemotherapy may improve drug response, suggesting ...
Greta Gudoityte +10 more
wiley +1 more source
, 2000 We prove that manifolds admitting a Riemannian metric for which products of harmonic forms are harmonic satisfy strong topological restrictions, some of which are akin to properties of flat manifolds. Others are more subtle, and are related to symplectic
Kotschick, D.
core +1 more source
Decrypting cancer's spatial code: from single cells to tissue niches
Molecular Oncology, EarlyView.Spatial transcriptomics maps gene activity across tissues, offering powerful insights into how cancer cells are organised, switch states and interact with their surroundings. This review outlines emerging computational, artificial intelligence (AI) and geospatial approaches to define cell states, uncover tumour niches and integrate spatial data with ...
Cenk Celik +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.We propose a context‐dependent model where the Duchenne muscular dystrophy (DMD) gene acts as a tumour suppressor in aggressive tumours and as an oncogene in less aggressive ones. We propose this model as a unified framework to explain the opposing survival associations with DMD expression and to guide experimental exploration of the dual role of DMD ...
Lee Machado +4 more
wiley +1 more source
IEEE Access, 2022 In this article, the significance of engineered ground planes in microstrip antennas and the effects of various configurations for the enhancements of the characteristics like isolation, cross-polarization levels, bandwidth and size reduction are vividly
Biswajit Dwivedy
doaj +1 more source