Results 51 to 60 of about 37,250 (282)

Imaging of High‐Risk Neuroblastoma: Recommendations From SIOPEN Radiology and Nuclear Medicine Specialty Committees

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Neuroblastoma is the most common extracranial solid tumor in early childhood. Its clinical behavior is highly variable, ranging from spontaneous regression to fatal outcome despite intensive treatment. The International Society of Pediatric Oncology Europe Neuroblastoma Group (SIOPEN) Radiology and Nuclear Medicine Specialty Committees ...
Annemieke Littooij   +11 more
wiley   +1 more source

Harmonic Numbers: Insights, Approximations and Applications

open access: yesSpreadsheets in Education, 2015
The applications of spreadsheets to mathematics allow learners to analyze mathematical ideas in ways never before possible. In this paper harmonic numbers are defined, calculated, approximated, and applied.
John A Rochowicz
doaj   +2 more sources

Time after time – circadian clocks through the lens of oscillator theory

open access: yesFEBS Letters, EarlyView.
Oscillator theory bridges physics and circadian biology. Damped oscillators require external drivers, while limit cycles emerge from delayed feedback and nonlinearities. Coupling enables tissue‐level coherence, and entrainment aligns internal clocks with environmental cues.
Marta del Olmo   +2 more
wiley   +1 more source

Some extensions of Chu's formulas and further combinatorial identities [PDF]

open access: yesMathematica Bohemica
We present some extensions of Chu's formulas and several striking generalizations of some well-known combinatorial identities. As applications, some new identities on binomial sums, harmonic numbers, and the generalized harmonic numbers are also derived.
Said Zriaa, Mohammed Mouçouf
doaj   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Some Congruences for Sums Involving Harmonic Numbers

open access: yesCumhuriyet Science Journal, 2018
In this paper, we establish some congruences involving sums withharmonic numbers and the terms of second-order linear sequences.
Neşe Ömür, Sibel Koparal
doaj   +1 more source

Parametric Euler Sums of Harmonic Numbers

open access: yes, 2022
We define a parametric variant of generalized Euler sums and construct contour integration to give some explicit evaluations of these parametric Euler sums. In particular, we establish several explicit formulas of (Hurwitz) zeta functions, linear and quadratic parametric Euler sums. Furthermore, we also give an explicit evaluation of alternating double
Quan, Junjie   +3 more
openaire   +3 more sources

Aggressive prostate cancer is associated with pericyte dysfunction

open access: yesMolecular Oncology, EarlyView.
Tumor‐produced TGF‐β drives pericyte dysfunction in prostate cancer. This dysfunction is characterized by downregulation of some canonical pericyte markers (i.e., DES, CSPG4, and ACTA2) while maintaining the expression of others (i.e., PDGFRB, NOTCH3, and RGS5).
Anabel Martinez‐Romero   +11 more
wiley   +1 more source

In vitro models of cancer‐associated fibroblast heterogeneity uncover subtype‐specific effects of CRISPR perturbations

open access: yesMolecular Oncology, EarlyView.
Development of therapies targeting cancer‐associated fibroblasts (CAFs) necessitates preclinical model systems that faithfully represent CAF–tumor biology. We established an in vitro coculture system of patient‐derived pancreatic CAFs and tumor cell lines and demonstrated its recapitulation of primary CAF–tumor biology with single‐cell transcriptomics ...
Elysia Saputra   +10 more
wiley   +1 more source

Combinatorial Identities with Multiple Harmonic-like Numbers

open access: yesAppliedMath
Multiple harmonic-like numbers are studied using the generating function approach. A closed form is stated for binomial sums involving these numbers and two additional parameters.
Kunle Adegoke, Robert Frontczak
doaj   +1 more source

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