Results 201 to 210 of about 1,458 (254)

Full‐Body AI Agent: A Perspective on Multi‐Scale Collaborative AI for Systemic Biology and Precision Medicine

Advanced Science, EarlyView.
We propose the Full‐Body AI Agent, a multi‐scale collaborative framework with 7 biological‐layer agents. It unifies multi‐omics/clinical data via standardized protocols, enabling phenotype‐guided closed‐loop reasoning, quantitative evaluation, and LLM safeguards, with promising applications in tumor metastasis modeling and precision drug development ...
Aoqi Wang, Jiajia Liu, Jianguo Wen, Yangyang Luo, Zhiwei Fan, Liren Yang, Xi Hu, Ruihan Luo, Yankai Yu, Sophia Li, Weiling Zhao, Xiaobo Zhou   +11 more
wiley   +1 more source

Symmetry reduction induced by argon tagging gives access to low-lying excited states of FeH⁺ in the overtone region of the Fe-H stretching mode.

Phys Chem Chem Phys
Jin S, Juanes M, van der Linde C, Ončák M, Beyer MK.   +4 more
europepmc   +1 more source

Reliable Modeling of Anharmonic Spectra Line-Shapes from VPT2 and Hybrid QM Models: IR Spectrum of Uracil as a Test Case. [PDF]

J Phys Chem A
Xu R, Yang Q, Bloino J, Biczysko M.
europepmc   +1 more source

Single‐Cell Dissection of Tumor‐Infiltrating Lymphocytes Reveals Cellular Architecture Predictive of Therapeutic Efficacy in Acral Melanoma

Advanced Science, EarlyView.
Autologous tumor‐infiltrating lymphocyte (TIL) therapy shows promising efficacy in acral melanoma, yet determinants of durable response remain unclear. By integrating single‐cell transcriptomics and TCR sequencing, this study reveals that TIL products enriched for T follicular helper and intermediate exhausted T cells establish persistent clonal ...
Chao Zhang, Wanyi Xiao, Hongru Shen, Fenge Li, Ting Li, Weihong Zhang, Haotian Liu, Ziwei Gao, Hongyu Wang, Xiubao Ren, Kexin Chen, Xiangchun Li, Jilong Yang   +12 more
wiley   +1 more source

Biotuner: A python toolbox integrating music theory and signal processing for harmonic analysis of physiological and natural time series. [PDF]

Brain Inform
Bellemare-Pepin A, Jerbi K.
europepmc   +1 more source

Leveraging Artificial Intelligence and Large Language Models for Cancer Immunotherapy

Advanced Science, EarlyView.
Cancer immunotherapy faces challenges in predicting treatment responses and understanding resistance mechanisms. Artificial intelligence (AI) and machine learning (ML) offer powerful solutions for cancer immunotherapy in patient stratification, biomarker discovery, treatment strategy optimization, and foundation model development.
Xinchao Wu, Mengtao Sun, Lusheng Li, Jieqiong Wang, Shibiao Wan   +4 more
wiley   +1 more source

Signatures of Antisymmetric Vibrations in the Ultrafast Dynamics of Quadrupolar Dyes. [PDF]

J Phys Chem Lett
Souri S, Winte K, Lünemann DC, Timmer D, Kraus T, Mena-Osteritz E, Bäuerle P, Tretiak S, Lienau C, De Sio A.   +9 more
europepmc   +1 more source

Mapping the “Supply–Demand–Flow” of Ecosystem Services for Ecosystem Management in China

Advanced Science, EarlyView.
This study develops a “supply–demand–flow” framework clarifies how ecosystem services move between regions by distinguishing potential and actual supply and demand. Using integrated biophysical–socioeconomic modeling, nine services in China were mapped.
Yikun Zhang, Yadong Yang, Yongsheng Wang, Guirui Yu   +3 more
wiley   +1 more source

Quartz Enhanced Photoacoustic Spectroscopy on Solid Samples. [PDF]

Sensors (Basel)
Falkhofen J, Bahr MS, Baumann B, Wolff M.   +3 more
europepmc   +1 more source

Zero-Point-Energy Driven Isotopic Exchange of the [H₃O]^- anion Probed by Mid-Infrared Action Spectroscopy. [PDF]

J Am Chem Soc
Dinu DF, Ončák M, Thorwirth S, Liedl KR, Brünken S, Schlemmer S, Jusko P.   +6 more
europepmc   +1 more source