Results 51 to 60 of about 1,219,741 (305)

Influence of microwave-assisted chemical treatment on delignification of rice straw biomass

open access: yesEnvironment Conservation Journal, 2021
Lignocellulosic biomass (like rice straw) provides an alternative for depleting non-renewable energy sources through its value-added utilization (like production of biofuels and nanocellulose) owing to its abundance, renewability, polymer presence and ...
Mohd Ishfaq Bhat   +4 more
doaj   +1 more source

pH‐mediated activation of the lysosomal arginine sensor SLC38A9

open access: yesFEBS Letters, EarlyView.
Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley   +1 more source

DeepPricing: pricing convertible bonds based on financial time-series generative adversarial networks

open access: yesFinancial Innovation, 2022
Convertible bonds are an important segment of the corporate bond market, however, as hybrid instruments, convertible bonds are difficult to value because they depend on variables related to the underlying stock, the fixed-income part, and the interaction
Xiaoyu Tan   +3 more
doaj   +1 more source

Development of Cookies Incorporated with Pomegranate Seed Powder and Defatted Soybean Flour

open access: yesInternational Journal of Fruit Science, 2022
Pomegranate seeds (PS) are valuable sources of bioactive phytochemicals and can be used as substrate for the production of nutritionally valuable and biologically active components that could find several applications as functional food ingredients, food
Harish T   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

open access: yesMolecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon   +13 more
wiley   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

open access: yesMolecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli   +7 more
wiley   +1 more source

Kepemimpinan Hamba Tuhan Menurut Matius 20:25-28

open access: yesEvangelikal: Jurnal Teologi Injili dan Pembinaan Warga Jemaat, 2019
: The leadership of God's servant raises a polemic because there are still those who think about God's servant being only servant and not being leader, however, in that opinion it is true.
Hannas Hannas, Rinawaty Rinawaty
doaj   +1 more source

Pre-Pinot Gris Harvest List [PDF]

open access: yes, 1991
This document outlines the tasks, supplies needed, and people scheduled to work for two days during the 1991 ...
Unknown,
core   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

open access: yesMolecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Drying and smoking of fish: nutritional significance, safety concerns and emerging technologies for food security

open access: yesJournal of Fisheries
The global demand for fish and fishery products has heightened the need for effective preservation methods to ensure food security and reduce post-harvest losses.
Nidhi Singh Sengar   +7 more
doaj   +1 more source

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