Results 51 to 60 of about 1,016,481 (309)
FEBS Letters, EarlyView.The process of internalization of the Shiga toxin A subunit via formation of a complex with the Shiga toxin B subunit, which specifically binds to the Gb3 receptor. The peptide is designed to act as a carrier of drugs into cancer cells. Here, we explored the potential of peptides derived from the catalytic A subunit of Shiga toxin (STxA) to be drug ...
Giulia Opassi +6 more
wiley +1 more source
Remote Sensing, 2020 On 10 August 2020, a series of intense and fast-moving windstorms known as a derecho caused widespread damage across Iowa’s (the top US corn-producing state) agricultural regions.
Mehdi Hosseini +9 more
doaj +1 more source
Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions
FEBS Letters, EarlyView.The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang +4 more
wiley +1 more source
Trends in post-disturbance recovery rates of Canada’s forests following wildfire and harvest
, 2016 The recovery of forests following stand-replacing disturbance is of widespread interest; however, there is both a lack of definitional clarity for the term “recovery” and a dearth of empirical data on the rates of forest recovery associated with ...
Samuel F. Bartels +3 more
semanticscholar +1 more source
Golgi enzymes are retrieved from the plasma membrane to the trans‐Golgi network
FEBS Letters, EarlyView.Golgi enzymes are traditionally considered resident proteins retained within the Golgi apparatus. Here, we demonstrate that a subset transiently reaches the cell surface and is subsequently retrieved to the trans‐Golgi network via retrograde transport. Using a nanobody‐based toolkit, we uncover a dynamic trafficking cycle of several Golgi enzymes.
Dominik P. Buser, Tina Junne
wiley +1 more source
Financial Innovation, 2022 Convertible bonds are an important segment of the corporate bond market, however, as hybrid instruments, convertible bonds are difficult to value because they depend on variables related to the underlying stock, the fixed-income part, and the interaction
Xiaoyu Tan +3 more
doaj +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Kepemimpinan Hamba Tuhan Menurut Matius 20:25-28
Evangelikal: Jurnal Teologi Injili dan Pembinaan Warga Jemaat, 2019 : The leadership of God's servant raises a polemic because there are still those who think about God's servant being only servant and not being leader, however, in that opinion it is true.
Hannas Hannas, Rinawaty Rinawaty
doaj +1 more source
The Effect of Harvest on Forest Soil Carbon: A Meta-Analysis
, 2016 Forest soils represent a substantial portion of the terrestrial carbon (C) pool, and changes to soil C cycling are globally significant not only for C sequestration but also for sustaining forest productivity and ecosystem services.
J. James, R. Harrison
semanticscholar +1 more source