Results 61 to 70 of about 550,312 (276)

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Harvest for schools

, 2012
This archived document is maintained by the Oregon State Library as part of the Oregon Documents Depository Program. It is for informational purposes and may not be suitable for legal purposes.Title from PDF caption (viewed on July 5, 2013)Mode of ...

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IMPDH inhibition enhances cytarabine efficacy in SAMHD1‐expressing leukaemia cells via guanine nucleotide depletion

Molecular Oncology, EarlyView.
Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla, Christopher Dirks, Caroline Eiden, Sonja K. Fesenmayer, Femke M. Hormann, Yolande Klootsema, Ingrid Lilienthal, Si Min Zhang, Nikolas Herold, Sean G. Rudd   +9 more
wiley   +1 more source

Navigating the Fault Lines in Civic Food Networks

Journal of Agriculture, Food Systems, and Community Development, 2016
Civic food networks have emerged as a civil society–driven response to the social, economic, and environmental shortcomings of the industrial food system.
Colin Ray Anderson, Wayne McDonald, Jo-Lene Gardiner, Stéphane M. McLachlan   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

INCORPORATION OF WITHIN-SEASON YIELD GROWTH INTO A MATHEMATICAL PROGRAMMING SUGARCANE HARVEST SCHEDULING MODEL [PDF]

This study focuses on the development of a optimal harvest scheduling mathematical programming model which incorporates within-season changes in perennial crop yields.
Salassi, Michael E., Champagne, Lonnie P., Legendre, Benjamin L.   +2 more
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Effect of Packaging Materials on Lettuce (Lactuca sativa var. capitata) Chemical Quality Under Cold Storage

International Journal of Food Science
Lettuce is a perishable vegetable with a short shelf life, which leads to detrimental changes in texture, physiological processes, and enzymatic activity during postharvest storage.
Vu Thi Kim Oanh, Tolcha Techane Alemu
doaj   +1 more source

Efficacy studies on ECO₂FUME® phosphine fumigant for complete control of Sitophilus zeamais and Tribolium castaneum in stored maize in Thailand

Julius-Kühn-Archiv, 2018
ECO₂FUME® fumigation of maize bag stacks under gas proof sheets was conducted to establish the optimal dosages (application rate) and exposure times (fumigation period) against mixed-age cultures of Sitophilus zeamais and Tribolium castaneum.
Kengkanpanich, Rungsima, Suthisut, Duangsamorn, Noochanapal, Pavinee, Pobsok, Panania   +3 more
doaj   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Economic Analysis of Post-harvest Losses in Marketing of Vegetables in Uttarakhand [PDF]

The study has examined the nature and extent of post-harvest losses in vegetable supply chain in the Kumaon division of Uttarakhand. Multistage cluster sampling has been used for selection of 80 vegetable growers, 40 farmers from the hilly region and 40 ...
Sharma, Gaurav, Singh, S.P.
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