Results 71 to 80 of about 1,016,481 (309)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Effect of Packaging Materials on Lettuce (Lactuca sativa var. capitata) Chemical Quality Under Cold Storage

International Journal of Food Science
Lettuce is a perishable vegetable with a short shelf life, which leads to detrimental changes in texture, physiological processes, and enzymatic activity during postharvest storage.
Vu Thi Kim Oanh, Tolcha Techane Alemu
doaj   +1 more source

Investigating the Antioxidant Potential of Mango Seed Kernel Polyphenols: Extraction and Optimization Strategies

Foods
Mango seed kernels, an underutilized by-product of the mango pulping industries, are a rich supplier of metabolites, specifically phenolic and flavonoid compounds. These compounds have potential health benefits.
Poonam Choudhary, Sandeep P. Dawange, Thingujam Bidyalakshmi, Ramesh Chand Kasana, Kairam Narsaiah, Bhupendra M. Ghodki   +5 more
doaj   +1 more source

Efficacy studies on ECO₂FUME® phosphine fumigant for complete control of Sitophilus zeamais and Tribolium castaneum in stored maize in Thailand

Julius-Kühn-Archiv, 2018
ECO₂FUME® fumigation of maize bag stacks under gas proof sheets was conducted to establish the optimal dosages (application rate) and exposure times (fumigation period) against mixed-age cultures of Sitophilus zeamais and Tribolium castaneum.
Kengkanpanich, Rungsima, Suthisut, Duangsamorn, Noochanapal, Pavinee, Pobsok, Panania   +3 more
doaj   +1 more source

KDM7A and KDM1A inhibition suppresses tumour promoting pathways in prostate cancer

Molecular Oncology, EarlyView.
Treatment resistance is a major challenge for patients with advanced prostate cancer. This study examined an alternative approach to target the major prostate cancer‐promoting pathway by targeting epigenetic factors, whose levels are higher in tumours.
Jennie N Jeyapalan, Veronika M Metzler, Simone de Brot, Corinne L Woodcock, Anna E Harris, Jennifer Lothion‐Roy, Emeli M Nilsson, Atara Ntekim, Michael S Toss, Jenny L Persson, Francesca Khani, Brian D Robinson, Lorraine J Gudas, Emad Rakha, David M Heery, Catrin S Rutland, Nigel P Mongan   +16 more
wiley   +1 more source

Parallelising Harvesting [PDF]

, 2006
Metadata harvesting has become a common technique to transfer a stream of data from one metadata repository or digital library system to another. As collections of metadata, and their associated digital objects, grow in size, the ingest of these items at the destination archive can take a significant amount of time, depending on the type of indexing or
openaire   +1 more source

Microbes promote amino acid harvest to rescue undernutrition in Drosophila

Cell Reports, 2015
Summary Microbes play an important role in the pathogenesis of nutritional disorders such as protein-specific malnutrition. However, the precise contribution of microbes to host energy balance during undernutrition is unclear.
R. Yamada, Sonali A Deshpande, K. Bruce, Elizabeth M Mak, W. Ja   +4 more
semanticscholar   +1 more source

Stimulator of interferon genes agonist augmented antitumor immunity of osimertinib in Egfr‐mutated lung cancer

Molecular Oncology, EarlyView.
Combining osimertinib with the STING agonist ADU‐S100 activates innate and adaptive immunity to overcome the non‐inflamed microenvironment of Egfr‐mutant lung cancer. This combination increases NK and CD8+ T‐cell infiltration, associated with activation of the STING‐IRF3 pathway and local immunogenic cell death.
Jun Nishimura, Tadahiro Kuribayashi, Johannes Brägelmann, Sachi Okawa, Masataka Taoka, Shunta Mori, Tomoka Nishimura, Takaaki Tanaka, Go Makimoto, Kiichiro Ninomiya, Kammei Rai, Eiki Ichihara, Ryohei Katayama, Katsuyuki Hotta, Masahiro Tabata, Yosuke Togashi, Yoshinobu Maeda, Martin L. Sos, Katsuyuki Kiura, Kadoaki Ohashi   +19 more
wiley   +1 more source

Physicochemical Properties and Storage Stability of Restructured Products Prepared from Mantis Shrimp at Refrigerated Temperature (4±1°C)

International Journal of Bio-Resource and Stress Management
The experiment was conducted from January to August, 2023 at Central Institute of Fisheries Education, Mumbai, Maharashtra, India, to evaluate nutritionally rich restructured fish products, such as sausages, using mantis shrimp (Miyakella nepa).
D. Varsha, A. K. Balange, P. Layana, R. P. Deepitha, D. Abuthagir Iburahim, S. A. Joshi, S. B. Gore   +6 more
doaj   +1 more source

USP29‐regulated noncanonical stabilization of the hypoxia‐inducible factor‐α in aggressive prostate cancer

Molecular Oncology, EarlyView.
We identify USP29 as the only DUB mirroring CA9 expression, a marker of hypoxia and HIF pathway activation associated with PCA aggressiveness. USP29 stabilizes HIF‐1α and HIF‐2α via a noncanonical mechanism that is independent of PHD/pVHL activity yet relies on proteasomal regulation, establishing USP29 as a previously unrecognized regulator of hypoxic
Amelie S Schober, Leire Moreno‐Cugnon, Laura Martínez‐Pérez, Amaia Ercilla, Amaia Zabala‐Letona, Adrián Vicente‐Barrueco, Maider Fagoaga‐Eugui, Saioa Garcia‐Longarte, Blanca Calle‐Ciborro, Encarnación Pérez‐Andrés, Onintza Carlevaris, Sara Pozo, Isabel Mendizabal, Ugo Mayor, Arkaitz Carracedo, Violaine Sée, Edurne Berra   +16 more
wiley   +1 more source