Results 191 to 200 of about 11,893 (260)

Prolonged IL‐33 Exposure Switches the Secreted Mast Cell Cytokine Profile From Pro‐Inflammatory to Pro‐Tolerant

open access: yesAllergy, Volume 81, Issue 3, Page 720-733, March 2026.
This study investigates the effect of IL‐33 and Hymenoptera venom on mast cell cytokine profiles under venom immunotherapy (VIT)‐like conditions. Our in vitro model of VIT‐like mast cell stimulation demonstrates a modulatory effect of IL‐33 on the secreted mast cell cytokine profile.
Andrea R. Teufelberger   +3 more
wiley   +1 more source

Implicit Promises and the Timing of Defined‐Benefit Pension Plan Freezes

open access: yesFinancial Management, Volume 55, Issue 1, Spring 2026.
ABSTRACT Firms time defined‐benefit (DB) plan freezes after CEO turnovers to protect CEO retirement benefits from cost cuts affecting the wider workforce. We document a significant increase in voluntary CEO turnovers just before the freeze, without notable post‐freeze changes.
Zacharias Petrou, Adamos Vlittis
wiley   +1 more source

Bioengineered AAV9 and Optimised Microdystrophin Vectors Augment Phenotypic Rescue in a Murine Model of Duchenne Muscular Dystrophy

open access: yesJournal of Cellular and Molecular Medicine, Volume 30, Issue 5, March 2026.
ABSTRACT Duchenne muscular dystrophy (DMD) is a severe neuromuscular disorder without an effective cure. Adeno‐associated virus (AAV) based gene therapy has improved dystrophin function, with sub‐optimal clinical outcomes. We reasoned that a combination of rational engineering of AAV9 capsids modified at the post‐translational modification sites ...
Mohankumar B. Senthilkumar   +14 more
wiley   +1 more source

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