Results 41 to 50 of about 5,246,438 (234)

Pediatric Idiopathic Multicentric Castleman Disease Is Often Severe But Responsive to Siltuximab

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Idiopathic multicentric Castleman disease (iMCD) is a potentially fatal immunologic disorder marked by widespread lymphadenopathy and inflammation. Siltuximab, an interleukin‐6 (IL‐6) inhibitor, is the only FDA‐approved treatment for adult patients with iMCD.
Bridget Austin, Sheila K. Pierson, Kelley C. Dacus, Mateo Sarmiento Bustamante, Saishravan Shyamsundar, Larissa Borys, Kayla McHugh, Abiola Irvine, Yoojin Jo, Adam Bagg, Mary Jo Lechowicz, Daisy Alapat, Amy Chadburn, Megan S. Lim, Gordan Srkalovic, Frits van Rhee, David C. Fajgenbaum, Joshua D. Brandstadter   +17 more
wiley   +1 more source

The Kansas Hazard Mitigation Strategy

, 2002
Rev. 2.; application/pdf; "January 2002.""This document is a comprehensive strategy developed by the state agencies of Kansas to create an effective, long-term approach to eliminate or reduce the vulnerability of Kansas' communities to the human ...
Kansas Hazard Mitigation Team.
core   +1 more source

Research on prediction method of hydrogen sulfide concentration in anaerobic pool of vegetable pickling industry based on multi-feature fusion

Scientific Reports
Anaerobic pools in the vegetable pickling industry are typical confined spaces where hydrogen sulfide (H2S) readily accumulates, leading to frequent fatal poisoning.
Heng Zhang, Juntong Liu, Yan Dong, Qi Zhang, Yan Qin, Yan Liu   +5 more
doaj   +1 more source

The Impact of the COVID‐19 Pandemic on Childhood Cancer Survival: A Population‐Based Assessment of Survival Patterns Between 2015 and 2023 in Germany

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Numerous international studies have reported declines in new cancer diagnoses, delayed diagnoses and disruptions in cancer treatment following the implementation of COVID‐19 pandemic public health measures, raising concerns that these effects may ultimately contribute to increased cancer mortality.
Friederike Erdmann, Maike Wellbrock, Javier Louro, Arndt Borkhardt, Martin Schrappe, Claudia Trübenbach, Desiree Grabow, Cécile M. Ronckers, Joachim Schüz   +8 more
wiley   +1 more source

Nicotinamide Riboside Alleviates the Neurotoxic Injury of Dendritic Spine Plasticity Mediated by Hypoxic Microglial Activation

Biomolecules
Exposure to hypoxia at high altitudes is significantly associated with impairments in learning and memory functions, as well as abnormalities in neuronal function and synaptic plasticity.
Jinchao Hou, Haowei Zhang, Xiaodong Huo, Ruili Guan, Boxuan Wang, Yuchen Wang, Fang Zhao, Xinqin Liu, Yang Hu, Congcong Zhuang, Yuankang Zou   +10 more
doaj   +1 more source

Referral Patterns and Diagnostic Timeliness in Pediatric Cancer: A Hospital‐Based Study in Indonesia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Timely diagnosis and treatment are critical for improving survival among children with cancer. In low‐ and middle‐income countries (LMICs), delays are common and may be influenced by fragmented referral pathways and diagnostic limitations.
Nur Melani Sari, Regina Hadi Putri, Fatimah Assyifa, Judith Spijkerman, Gertjan Johannes Kaspers, Susi Susanah   +5 more
wiley   +1 more source

Association between pre-S/S amino acid variations of hepatitis B virus and hepatitis B surface antigen clearance

Zhongguo gonggong weisheng
ObjectiveAnalysis of the association between hepatitis B surface antigen (HBsAg) clearance and amino acid mutations in the pre-S/S region of the hepatitis B virus (HBV) in a cohort from Wuwei city, Gansu province.
Yuemei WANG, Xiaojie YUAN, Weilu ZHANG, Zhaohua JI, Zhen HE, Ting FU, Weikang WU, Haowei ZHOU, Yijun LI, Linli XU, Wenhua ZHANG, Wenling JIA, Chunhui LIANG, Haitao TANG, Fengmei WANG, Chunmei ZHAO, Zhongjun SHAO   +16 more
doaj   +1 more source

Venetoclax‐Based Therapy as a Bridge to Hematopoietic Stem Cell Transplantation in Relapsed or Refractory Pediatric Acute Leukemia

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Relapsed and/or refractory (R/R) pediatric acute leukemia carries a dismal prognosis, largely driven by chemoresistance to conventional salvage therapy. The BH3‐mimetic venetoclax, combined with chemotherapy or hypomethylating agents, has demonstrated efficacy in small clinical trials.
Katherine S. Colman, Deborah Meyran, Vajiranee Malalasekera, Heather Weerdenburg, Janine Campbell, Rachel Conyers, Stacie Wang, Hannah Walker, Seong Lin Khaw, Diane Hanna   +9 more
wiley   +1 more source

Technological Hazard Characterization

, 2017
In the framework of Natech risk assessment, technological hazard refers to a potential for the occurrence of adverse effects due to the release of hazardous substances, from process or storage equipment, caused by natural-hazard impacts.
Cozzani, V., V. Cozzani, Salzano, E., E. Salzano   +3 more
core   +1 more source

Other title: Hazard Mitigation Plan

, 2013
[Revised] October 14, 2013 Includes bibliographical and internet references.The purpose of the Kansas Hazard Mitigation Plan is to guide hazard mitigation to better protect the people and property of the State.
Kansas Hazard Mitigation Team.
core   +1 more source