Results 101 to 110 of about 675,507 (294)
The Bernstein-Von Mises Theorem in Semiparametric Competing Risks Models [PDF]
Semiparametric Bayesian models are nowadays a popular tool in survival analysis. An important area of research concerns the investigation of frequentist properties of these models.
Nils L. Hjort, Pierpaolo De Blasi
core
The newfound relationship between extrachromosomal DNAs and excised signal circles
FEBS Letters, EarlyView.Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley +1 more source
A Bounded Sine Skewed Model for Hydrological Data Analysis
AnalyticsHydrological time series frequently exhibit periodic trends with variables such as rainfall, runoff, and evaporation rates often following annual cycles. Seasonal variations further contribute to the complexity of these data sets.
Tassaddaq Hussain +3 more
doaj +1 more source
Discrete Additive Weibull Geometric Distribution
Journal of Statistical Theory and Applications (JSTA), 2019 Discretizing a continuous distribution has received much attention among researchers recently. Discrete analogue of the well-known continuous distributions such as Normal, Exponential, Weibull, Laplace, Rayleigh, and so on, are available in the ...
K. Jayakumar, M. Girish Babu
doaj +1 more source
Effects of extended unemployment insurance benefits: evidence from the monthly CPS [PDF]
This paper attempts to quantify the effects of extended unemployment insurance benefits in recent years. Using the monthly Current Population Survey, I estimate unemployment-to-employment (UE) hazard function and unemployment-to-inactivity (UN) hazard ...
Shigeru Fujita
core
Tests for Comparing Mark-Specific Hazards and Cumulative Incidence Functions [PDF]
, 2003 It is of interest in some applications to determine whether there is a relationship between a hazard rate function (or a cumulative incidence function) and a mark variable which is only observed at uncensored failure times. We develop nonparametric tests
Gilbert, Peter B. +2 more
core +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
The Availability of Systems with Bathtub Hazard Rate Function
JOURNAL OF ADVANCES IN MATHEMATICS, 2018 In our normal life we can see that the most realistic systems possess useful time governed by hazard rateof bathtub shaped. The hazard rate function, however, plays a vital role in the computation of theavailability function. The repair time, however, could be modeled as any statistical distribution.
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source