Results 81 to 90 of about 15,506,173 (331)

Circulating microRNA signatures of cachexia and cancer in Canis familiaris as a comparative oncology model for human disease

open access: yesMolecular Oncology, EarlyView.
Circulating microRNAs as biomarkers of cachexia and sex‐specific cancer in senior dogs. In 25 client‐owned dogs, four circulating miRNAs (miR‐15a, miR‐15b, miR‐16, miR‐140) were downregulated in cachexia, with miR‐16 the strongest individual biomarker (AUC = 0.899).
Soon‐Seok Park   +6 more
wiley   +1 more source

Bias in nearest-neighbor hazard estimation [PDF]

open access: yes
In nonparametric curve estimation, the smoothing parameter is critical for performance. In order to estimate the hazard rate, we compare nearest neighbor selectors that minimize the quadratic, the Kullback-Leibler, and the uniform loss.
Weißbach, Rafael, Dette, Holger
core  

Stochastic Comparisons of Parallel and Series Systems with Type II Half Logistic-Resilience Scale Components

open access: yesMathematics, 2020
This paper deals with stochastic comparisons of two parallel (series) systems with Type II half logistic-resilience scale (TIIHL-RS) distribution components with different baseline distribution functions.
Junrui Wang, Rongfang Yan, Bin Lu
doaj   +1 more source

Translating whole‐genome doubling into precision medicine in cancer

open access: yesMolecular Oncology, EarlyView.
Whole‐genome doubling creates a WGD‐positive tumor state characterized by persistent chromosomal instability, karyotypic diversification, and cellular stress. These same biological pressures drive aggressive tumor evolution while exposing therapeutic vulnerabilities, providing a rationale for WGD‐informed precision medicine. Whole‐genome doubling (WGD)
Sejung Lee, Junghyeok Lim, Jinhyuk Bhin
wiley   +1 more source

PANoptosis in the pathogenesis of myelodysplastic syndromes

open access: yesMolecular Oncology, EarlyView.
PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla   +4 more
wiley   +1 more source

Multivariate hazard orderings of discrete random vectors [PDF]

open access: yes
The task of comparing two random vectors with respect to some multivariate stochastic ordering usually involves an infinite number of comparisons. Dyckerhoff and Mosler (1997) proved that, when the random vectors have finite supports, this task, for some
Colangelo Antonio
core  

Studies on the flame propagation characteristic and thermal hazard of the premixed N2O/fuel mixtures

open access: yesDefence Technology, 2020
An experimental study was carried out to investigate the flame propagation and thermal hazard of the premixed N2O/fuel mixtures, including NH3, C3H8 and C2H4.
Yu-yan Li   +5 more
doaj   +1 more source

Intrapatient tumour heterogeneity and clonal evolution in an autopsy study of metastatic salivary gland cancer

open access: yesMolecular Oncology, EarlyView.
Tumour heterogeneity and clonal evolution of metastatic salivary gland cancer were evaluated in two patients with adenoid carcinoma and one patient with myoepithelial carcinoma. Radiology‐guided autopsy enabled multi‐region sampling (total samples n = 149), followed by whole‐genome sequencing and phylogenetic reconstruction (17 tumour samples, 4–7 per ...
Gerben Lassche   +10 more
wiley   +1 more source

Types of Hazard - Drag and Drop Activity

open access: yes, 2011
A drag and drop activity on types of hazard (flash file)
hazard, LSN, Q Projects, Bede College
core  

A New Generalized Two-Sided Class of the Distributions Via New Transmuted Two-Sided Bounded Distribution

open access: yesJournal of Statistical Theory and Applications (JSTA), 2019
In the present paper, we first consider a generalization of the standard two-sided power distribution so-called the transmuted two-sided distribution, and then extend proposed idea to generalized two-sided class of distributions, introduced by Korkmaz ...
O. Kharazmi, M. Zargar
doaj   +1 more source

Home - About - Disclaimer - Privacy