A note on methods for analysis of time to event data and interpretation of hazard ratio.
Trkulja V, Hrabač P.
europepmc +7 more sources
Odds ratio, hazard ratio and relative risk
Odds ratio (OR) is a statistic commonly encountered in professional or scientific medical literature. Most readers perceive it as relative risk (RR), although most of them do not know why that would be true. But since such perception is mostly correct, there is nothing (or almost nothing) wrong with that.
Janez Stare, Delphine Maucort-Boulch
semanticscholar +5 more sources
Limitations of the incidence density ratio as approximation of the hazard ratio [PDF]
Background Incidence density ratios (IDRs) are frequently used to account for varying follow-up times when comparing the risks of adverse events in two treatment groups.
Ralf Bender, Lars Beckmann
doaj +6 more sources
Hazard Ratio and Hazard Index as Preliminary Estimators Associated to the Presence of Furans and Alkylfurans in Belgian Foodstuffs [PDF]
This paper provides an estimation of the hazard related to the presence of furan and five alkyl furans (2- and 3-methylfuran, 2-ethylfuran, 2,5- and 2,3-dimethylfuran) in foodstuffs available in the Belgian market.
Zouheir Alsafra+4 more
doaj +4 more sources
Rare Event Approximation Between Subdistribution Hazard Ratio and Cause-specific Hazard Ratio in Survival Analysis With Competing Risks [PDF]
Background: Despite the fact that competing risks are inevitable in epidemiological and clinical studies, distinctions between the hazard ratio estimated by handling competing risks as censoring and the subditribution hazard ratio are often overlooked ...
Shiro Tanaka
doaj +3 more sources
A note on the magnitude of hazard ratios [PDF]
Andrés Azuero
semanticscholar +5 more sources
Cardiovascular disease burden from ambient air pollution in Europe reassessed using novel hazard ratio functions. [PDF]
Aims Ambient air pollution is a major health risk, leading to respiratory and cardiovascular mortality. A recent Global Exposure Mortality Model, based on an unmatched number of cohort studies in many countries, provides new hazard ratio functions ...
Lelieveld J+6 more
europepmc +2 more sources
The Hazards of Period Specific and Weighted Hazard Ratios [PDF]
How to adequately handle nonproportional hazards (NPH) in clinical trials is an important and timely question, particularly given recent advances in immuno-oncology treatments, in which survival cu...
Jonathan W. Bartlett+5 more
openaire +6 more sources
Causal interpretation of the hazard ratio in randomized clinical trials. [PDF]
Background: Although the hazard ratio has no straightforward causal interpretation, clinical trialists commonly use it as a measure of treatment effect. Methods: We review the definition and examples of causal estimands.
Fay MP, Li F.
europepmc +2 more sources
Instrumental Variable Estimation of the Causal Hazard Ratio [PDF]
AbstractCox's proportional hazards model is one of the most popular statistical models to evaluate associations of exposure with a censored failure time outcome. When confounding factors are not fully observed, the exposure hazard ratio estimated using a Cox model is subject to unmeasured confounding bias.
Linbo Wang+3 more
openaire +4 more sources