Results 161 to 170 of about 6,289,424 (361)

Assessing and improving the reliability of meta-analyses of hazard ratios derived from published time-to-event data [PDF]

, 2013
Jayne F. Tierney, David J. Fisher, Sarah Burdett, Lesley Stewart, Mahesh Parmar   +4 more
openalex   +1 more source

Unveiling unique protein and phosphorylation signatures in lung adenocarcinomas with and without ALK, EGFR, and KRAS genetic alterations

Molecular Oncology, EarlyView.
Proteomic and phosphoproteomic analyses were performed on lung adenocarcinoma (LUAD) tumors with EGFR, KRAS, or EML4–ALK alterations and wild‐type cases. Distinct protein expression and phosphorylation patterns were identified, especially in EGFR‐mutated tumors. Key altered pathways included vesicle transport and RNA splicing.
Fanni Bugyi, Mirjam Balbisi, Simon Sugár, Lóránd Váncza, Eszter Regős, Ilona Kovalszky, Ibolya Laczó, Tünde Harkó, Gábor Kecskeméti, Zoltán Szabó, Judit Moldvay, László Drahos, Lilla Turiák   +12 more
wiley   +1 more source

Hazard ratio: cuando el riesgo varía a lo largo del tiempo [PDF]

, 2015
Manuel Molina Arias
openalex   +1 more source

Hedging Pure Endowments with Mortality Derivatives [PDF]

, 2010
In recent years, a market for mortality derivatives began developing as a way to handle systematic mortality risk, which is inherent in life insurance and annuity contracts.
Wang, Ting, Young, Virginia R.
core  

RKIP overexpression reduces lung adenocarcinoma aggressiveness and sensitizes cells to EGFR‐targeted therapies

Molecular Oncology, EarlyView.
RKIP, a metastasis suppressor protein, modulates key oncogenic pathways in lung adenocarcinoma. In silico analyses linked low RKIP expression to poor survival. Functional studies revealed RKIP overexpression reduces tumor aggressiveness and enhances sensitivity to EGFR‐targeted therapies, while its loss promotes resistance.
Ana Raquel‐Cunha, Joana Pinheiro, Rui F. Marques, Patrícia Fontão, Diana Cardoso‐Carneiro, Adriana Mendes, Izabela N. F. Gomes, Ana Carolina Laus, Renato J. da Silva‐Oliveira, Rui Manuel Reis, Olga Martinho   +10 more
wiley   +1 more source

Intake Biomarkers for Nutrition and Health: Review and Discussion of Methodology Issues

Metabolites
Metabolomics profiles from blood, urine, or other body fluids have the potential to assess intakes of foods and nutrients objectively, thereby strengthening nutritional epidemiology research.
Ross L. Prentice
doaj   +1 more source

The restricted mean survival time as a replacement for the hazard ratio and the number needed to treat in long-term studies. [PDF]

ESC Heart Fail, 2021
Messori A, Bartoli L, Trippoli S.
europepmc   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Time dependent hazard ratio estimation using instrumental variables without conditioning on an omitted covariate. [PDF]

BMC Med Res Methodol, 2021
MacKenzie TA, Martinez-Camblor P, O'Malley AJ.   +2 more
europepmc   +1 more source

The Hazards of Hazard Ratios [PDF]

Epidemiology, 2010
openaire   +3 more sources