Results 171 to 180 of about 6,418,358 (332)

Workplace stress and its impact on the 16-year risk of myocardial infarction and stroke in an open female population aged 25—64 years in Russia/Siberia (WHO MONICA-psychosocial program)

open access: yesТерапевтический архив, 2015
Aim. To determine the impact of workplace stress on the hazard ratio (HR) of myocardial infarction (MI) and stroke in an open female population aged 25—64 years in Russia/Siberia (Novosibirsk) for 16 years. Subjects and methods.
V V Gafarov   +4 more
doaj  

Autophagosome marker, LC3, is released extracellularly via several distinct pathways

open access: yesFEBS Open Bio, EarlyView.
This study establishes a novel HiBiT‐tagging system for ultrasensitive detection of LC3, revealing multiple pathways for its extracellular secretion. It demonstrates that LC3 is released via both autophagy‐dependent and ‐independent mechanisms, including a novel route for nonlipidated LC3‐I.
Koki Saito   +3 more
wiley   +1 more source

Metformin promotes mitochondrial integrity through AMPK‐signaling in Leber's hereditary optic neuropathy

open access: yesFEBS Open Bio, EarlyView.
Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid   +3 more
wiley   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

open access: yesFEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili   +2 more
wiley   +1 more source

Consequences of Depletion of Susceptibles for Hazard Ratio Estimators Based on Propensity Scores. [PDF]

open access: yesEpidemiology, 2020
Fireman B   +12 more
europepmc   +1 more source

Trends and Disparities in Lung Cancer and Respiratory Failure Mortality in the United States: A 24‐Year Retrospective Study

open access: yesAging and Cancer, EarlyView.
Mortality from lung cancer and respiratory failure in US adults declined until 2010 but increased thereafter, with notable disparities by sex, race, region, and urbanicity. This 24‐year analysis highlights rising post‐2010 mortality in women, non‐Hispanic Whites, and urban areas, underscoring the need for targeted public health interventions.
Sardar M. I. Khan   +10 more
wiley   +1 more source

Institutions, Bargaining Power and Labor Shares [PDF]

open access: yes
We use a static framework characterized by both moral hazard and holdup problems. In the model the optimal allocation of bargaining power balances these frictions.
Benjamin Bental, Dominique Demougin
core  

Subtleties in the interpretation of hazard contrasts

open access: yesLifetime Data Analysis, 2020
T. Martinussen   +2 more
semanticscholar   +1 more source

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