Results 171 to 180 of about 6,212,855 (344)

Biased Social Learning [PDF]

This paper examines social learning when only one of the two types of decisions is observable. Because agents arrive randomly over time, and only those who invest are observed, later agents face a more complicated inference problem than in the standard ...
Helios Herrera, Johannes Horner
core  

Unraveling LINE‐1 retrotransposition in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
The novel RetroTest method allows the detection of L1 activation in clinical samples with low DNA input, providing global L1 activity and the identification of the L1 source element. We applied RetroTest to a real‐world cohort of HNSCC patients where we reported an early L1 activation, with more than 60% of T1 patients showing L1 activity.
Jenifer Brea‐Iglesias, Ana Oitabén, Sonia Zumalave, Bernardo Rodriguez‐Martin, María Gallardo‐Gómez, Martín Santamarina, Ana Pequeño‐Valtierra, Laura Juaneda‐Magdalena, Ramón García‐Escudero, José Luis López‐Cedrún, Máximo Fraga, José M. C. Tubio, Mónica Martínez‐Fernández   +12 more
wiley   +1 more source

Relative effectiveness of a heterologous booster dose with adenovirus type 5 vectored COVID-19 vaccine versus three doses of inactivated COVID-19 vaccine in adults during a nationwide outbreak of omicron predominance, in China: a retrospective, individually matched cohort-control study

Emerging Microbes and Infections
Effectiveness of heterologous booster regimes with ad5 vectored COVID-19 vaccine in a large, diverse population during the national-scale outbreak of SARS-CoV-2 omicron predominance in China has not been reported, yet.
Siyue Jia, Zundong Yin, Hongxing Pan, Fuzhen Wang, Xiaoqiang Liu, Qing Wang, Li Zhang, Jihai Tang, Hao Yang, Jiangbo Du, Zhiguo Wang, Pengfei Jin, Zhihang Peng, Rong Tang, Guodong Kang, Xuewen Wang, Simin Li, Weixiao Wang, Jingxin Li, Hongbing Shen, Fengcai Zhu   +20 more
doaj   +1 more source

The Hazards of Hazard Ratios [PDF]

Epidemiology, 2010
openaire   +3 more sources

BMP antagonist CHRDL2 enhances the cancer stem‐cell phenotype and increases chemotherapy resistance in colorectal cancer

Molecular Oncology, EarlyView.
Overexpression of CHRDL2 in colon cancer cells makes them more stem‐like and resistant to chemo‐ and radiotherapy. CHRDL2‐high cells have upregulation of the WNT pathway, genes involved in the DNA damage response (DDR) pathway and epithelial‐to‐mesenchymal transition (EMT). This leads to quicker repair of damaged DNA and more cell migration.
Eloise Clarkson, Annabelle Lewis
wiley   +1 more source

Differential impact of SARS-CoV-2 infection during different outbreak periods on incident diabetes in Japan: a matched cohort study utilizing health insurance claims

Environmental Health and Preventive Medicine
Background: An increased risk of diabetes after COVID-19 exposure has been reported in Caucasians during the early phase of the pandemic, but the effects across viral variants and in non-Caucasians have not been evaluated.
Akiko Matsumoto, Sachiko Kodera, Tatsuya Matsuura, Yoko Takayama, Yuya Yamada, Akimasa Hirata   +5 more
doaj   +1 more source

IV estimation of causal hazard ratio

, 2018
Cox's proportional hazards model is one of the most popular statistical models to evaluate associations of exposure with a censored failure time outcome. When confounding factors are not fully observed, the exposure hazard ratio estimated using a Cox model is subject to unmeasured confounding bias.
Wang, Linbo, Tchetgen, Eric Tchetgen, Martinussen, Torben, Vansteelandt, Stijn   +3 more
openaire   +2 more sources

Comparing Cost-Effectiveness Of Emerging Drugs In Advanced Cancer Without Hazard Ratios For Progression [PDF]

, 2015
Witold Więcek, Hélène Karcher
openalex   +1 more source

A Sensitivity Analysis Approach for the Causal Hazard Ratio in Randomized and Observational Studies [PDF]

, 2022
Rachel Axelrod, Daniel Nevo
openalex   +1 more source

Tumor clusters with divergent inflammation and human retroelement expression determine the clinical outcome of patients with serous ovarian cancer

Molecular Oncology, EarlyView.
Analysis of treatment‐naïve high‐grade serous ovarian carcinoma (HGSOC) and control tissues for ERVs, LINE‐1 (L1), inflammation, and immune checkpoints identified five clusters with diverse patient recurrence‐free survivals. An inflammation score was calculated and correlated with retroelement expression, where one novel cluster (Triple‐I) with high ...
Laura Glossner, Markus Eckstein, Christoph Mark, Matthias W. Beckmann, Arndt Hartmann, Pamela L. Strissel, Reiner Strick   +6 more
wiley   +1 more source