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Network meta-analysis on the log-hazard scale, combining count and hazard ratio statistics accounting for multi-arm trials: a tutorial. [PDF]

open access: yesBMC Medical Research Methodology, 2010
BACKGROUND: Data on survival endpoints are usually summarised using either hazard ratio, cumulative number of events, or median survival statistics. Network meta-analysis, an extension of traditional pairwise meta-analysis, is typically based on a single
A Ades   +31 more
core   +3 more sources

Hazard Ratio Analysis of Laparoscopic Radical Hysterectomy for IA1 With LVSI-IIA2 Cervical Cancer: Identifying the Possible Contraindications of Laparoscopic Surgery for Cervical Cancer [PDF]

open access: yesFrontiers in Oncology, 2020
Objectives: This study aimed to compare the 5-year disease-free survival (DFS) and overall survival (OS) of laparoscopic radical hysterectomy (LRH) and abdominal radical hysterectomy (ARH) for IA1 with lymphovascular space invasion (LVSI)-IIA2 cervical ...
Pengfei Li   +8 more
doaj   +2 more sources

Hazard Ratio in Clinical Trials [PDF]

open access: yesAntimicrobial Agents and Chemotherapy, 2004
Time-to-event curves analyzed by Cox proportional hazards regression are commonly used to describe the outcome of drug studies. This methodology has the advantage of using all available information, including patients who fail to complete the trial, such
S. Spruance   +3 more
semanticscholar   +4 more sources

The Hazard Ratio Is Equivalent to an Odds Under the Assumption of Proportional Hazards [PDF]

open access: yesJournal of Patient-Centered Research and Reviews
Clinicians routinely interpret statistical findings from medical research to inform patients of treatment benefits. Studies that use the hazard ratio present special challenges.
David M. Thompson
doaj   +2 more sources

Estimation of the ratio of hazard functions [PDF]

open access: bronze, 1982
In a clinical trial in which comparison of survival across treatment groups is of interest, it is useful to have a descriptive measure of the difference in survival between groups. If the hazard functions in two groups are roughly proportional, then the ratio of hazard functions has the interpretation of relative risk and has intuitive appeal as a ...
John Crowley   +2 more
openalex   +4 more sources

The Hazards of Period Specific and Weighted Hazard Ratios [PDF]

open access: greenStatistics in Biopharmaceutical Research, 2020
How to adequately handle nonproportional hazards (NPH) in clinical trials is an important and timely question, particularly given recent advances in immuno-oncology treatments, in which survival cu...
Jonathan W. Bartlett   +5 more
openalex   +6 more sources

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