Results 21 to 30 of about 6,466,330 (328)

The Hazards of Period Specific and Weighted Hazard Ratios [PDF]

open access: yesStatistics in Biopharmaceutical Research, 2020
How to adequately handle nonproportional hazards (NPH) in clinical trials is an important and timely question, particularly given recent advances in immuno-oncology treatments, in which survival cu...
Jonathan W. Bartlett   +5 more
openaire   +4 more sources

Blood pressure variability and cardiovascular risk in the PROspective study of pravastatin in the elderly at risk (PROSPER) [PDF]

open access: yes, 2012
Variability in blood pressure predicts cardiovascular disease in young- and middle-aged subjects, but relevant data for older individuals are sparse. We analysed data from the PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) study of ...
A Frattola   +41 more
core   +3 more sources

Ceramide remodeling and risk of cardiovascular events and mortality [PDF]

open access: yes, 2018
BackgroundRecent studies suggest that circulating concentrations of specific ceramide species may be associated with coronary risk and mortality. We sought to determine the relations between the most abundant plasma ceramide species of differing acyl ...
Dorr, Marcus   +14 more
core   +2 more sources

Association of Accelerometry-Measured Physical Activity and Cardiovascular Events in Mobility-Limited Older Adults: The LIFE (Lifestyle Interventions and Independence for Elders) Study. [PDF]

open access: yes, 2017
BACKGROUND:Data are sparse regarding the value of physical activity (PA) surveillance among older adults-particularly among those with mobility limitations. The objective of this study was to examine longitudinal associations between objectively measured
Abbie Wrights   +124 more
core   +2 more sources

What’s the Risk: Differentiating Risk Ratios, Odds Ratios, and Hazard Ratios? [PDF]

open access: yesCureus, 2020
Risk ratios, odds ratios, and hazard ratios are three common, but often misused, statistical measures in clinical research. In this paper, the authors dissect what each of these terms define, and provide examples from the medical literature to illustrate each of these statistical measures.
George, Andrew   +2 more
openaire   +2 more sources

Ectopy on a single 12‐lead ECG, incident cardiac myopathy, and death in the community [PDF]

open access: yes, 2017
BackgroundAtrial fibrillation and heart failure are 2 of the most common diseases, yet ready means to identify individuals at risk are lacking. The 12-lead ECG is one of the most accessible tests in medicine.
Alonso, Alvaro   +11 more
core   +3 more sources

Neutrophil-to-lymphocyte ratio and mortality in the United States general population

open access: yesScientific Reports, 2021
The neutrophil-to-lymphocyte ratio (NLR) in peripheral blood reflects the balance between systemic inflammation and immunity and is emerging as a prognostic biomarker in many diseases, but its predictive role for mortality in the general population has ...
Minkyo Song   +3 more
semanticscholar   +1 more source

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