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Bayesian analysis for monotone hazard ratio
Lifetime Data Analysis, 2010We propose a Bayesian approach for estimating the hazard functions under the constraint of a monotone hazard ratio. We construct a model for the monotone hazard ratio utilizing the Cox's proportional hazards model with a monotone time-dependent coefficient.
Kim, Yongdai +2 more
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An explanation of the hazard ratio
Pharmaceutical Statistics, 2004Several months ago someone attended a course for non-statisticians that I was running and said, ‘If I can go away from this course understanding what a hazard ratio is then it will have been worthwhile!’ Well, here goes. The hazard ratio, like the odds ratio, is not only difficult to explain but its use and interpretation continue to confuse both ...
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On the interpretation of the hazard ratio in Cox regression
Biometrical Journal, 2019AbstractWe argue that the term “relative risk” should not be used as a synonym for “hazard ratio” and encourage to use the probabilistic index as an alternative effect measure for Cox regression. The probabilistic index is the probability that the event time of an exposed or treated subject exceeds the event time of an unexposed or untreated subject ...
Jan De Neve, Thomas A. Gerds
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BMJ, 2011
Researchers investigated the extent to which referral from primary care for defined symptoms of hip pain varied by age, sex, and social deprivation in the United Kingdom. A cohort study design was used. Data for individual patients registered at 326 general practices between 2001 and 2007 were extracted from the health improvement network database in ...
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Researchers investigated the extent to which referral from primary care for defined symptoms of hip pain varied by age, sex, and social deprivation in the United Kingdom. A cohort study design was used. Data for individual patients registered at 326 general practices between 2001 and 2007 were extracted from the health improvement network database in ...
openaire +1 more source
Hazards of Hazard Ratios — Deviations from Model Assumptions in Immunotherapy
New England Journal of Medicine, 2018Look Beyond Hazard Ratios Many trials are based on the proportional-hazards assumption that an event is equally likely in different treatment groups over time and deviations are related to the intervention. Full Kaplan–Meier estimates from earlier trials may be more informative than summary statistics.
Brian M. Alexander +2 more
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Estimation of the Hazards Ratio in Two Grouped Samples
Biometrics, 1985A simple estimator of the hazards ratio of two grouped samples is proposed. If the number of time grouping intervals is fixed, the following asymptotics hold: unbiasedness, and full efficiency when the true hazards ratio is 1 and the probability of failure in each interval is small.
Moreau, T. +3 more
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Nonparametric Estimation of the Hazard Ratio
Journal of the American Statistical Association, 1984Abstract A nonparametric estimate of the hazard ratio function is developed and applied to the time-dependent survival advantage of having achieved an objective response to treatment for a given disease. The method computes the total exposure to risk of failure, or dying, among patients in either of two disease states (nonresponder/responder).
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Cancer statistics for the US Hispanic/Latino population, 2021
Ca-A Cancer Journal for Clinicians, 2021Kimberly D Miller +2 more
exaly
Cancer risk among World Trade Center rescue and recovery workers: A review
Ca-A Cancer Journal for Clinicians, 2022Paolo Boffetta +2 more
exaly