Results 31 to 40 of about 6,466,330 (328)

Preoperative neutrophil-lymphocyte ratio and outcome from coronary artery bypass grafting [PDF]

, 2007
Background: An elevated preoperative white blood cell count has been associated with a worse outcome after coronary artery bypass grafting (CABG). Leukocyte subtypes, and particularly the neutrophil-lymphocyte (N/L) ratio, may however, convey superior ...
Buchan, Keith G., Croal, Bernard L., Cuthbertson, Brian, El-Shafei, Hussein, Gibson, George, Gibson, Patrick H., Hillis, Graham S., Ifezulike, Ada I., Jeffrey, Robert R., Small, Gary R.   +9 more
core   +1 more source

Liraglutide and Cardiovascular Outcomes in Type 2 Diabetes [PDF]

, 2016
Background The cardiovascular effect of liraglutide, a glucagon-like peptide 1 analogue, when added to standard care in patients with type 2 diabetes, remains unknown. Methods In this double-blind trial, we randomly assigned patients with type 2 diabetes
Bergenstal, RM, Brown-Frandsen, K, Buse, JB, Daniels, GH, Kristensen, P, LEADER Steering Committee on behalf of the LEADER Trial Investigators, Mann, JF, Marso, SP, Nauck, MA, Nissen, SE, Pocock, S, Poulter, NR, Ravn, LS, Steinberg, WM, Stockner, M, Zinman, B   +15 more
core   +1 more source

Duration of adjuvant chemotherapy for stage III colon cancer [PDF]

, 2018
BACKGROUND Since 2004, a regimen of 6 months of treatment with oxaliplatin plus a fluoropyrimidine has been standard adjuvant therapy in patients with stage III colon cancer.
Andre, Thierry, Boukovinas, Ioannis, Grothey, Axel, Iveson, Timothy, Kerr, Rachel, Labianca, Roberto, Meyerhardt, Jeffrey A., Meyers, Jeffrey P., Niedzwiecki, Donna, Paul, James, Renfro, Lindsay A., Sargent, Daniel J., Saunders, Mark, Shi, Qian, Shields, Anthony F., Sobrero, Alberto F., Souglakos, John, Taieb, Julien, Torri, Valter, Vernerey, Dewi, Watanabe, Toshiaki, Yamanaka, Takeharu, Yoshino, Takayuki   +22 more
core   +1 more source

Impact of breast cancer subtypes on 3-year survival among adolescent and young adult women. [PDF]

, 2013
IntroductionYoung women have poorer survival after breast cancer than do older women. It is unclear whether this survival difference relates to the unique distribution of hormone receptor (HR) and human epidermal growth factor receptor 2 (HER2)-defined ...
Clarke, Christina A, DeRouen, Mindy C, Gomez, Scarlett L, Keegan, Theresa HM, Kurian, Allison W, Press, David J, Tao, Li   +6 more
core   +2 more sources

Restricted mean survival time: an alternative to the hazard ratio for the design and analysis of randomized trials with a time-to-event outcome

BMC Medical Research Methodology, 2013
BackgroundDesigns and analyses of clinical trials with a time-to-event outcome almost invariably rely on the hazard ratio to estimate the treatment effect and implicitly, therefore, on the proportional hazards assumption.
P. Royston, M. Parmar
semanticscholar   +1 more source

Coronary CT Angiography and 5-Year Risk of Myocardial Infarction. [PDF]

, 2018
BACKGROUND: Although coronary computed tomographic angiography (CTA) improves diagnostic certainty in the assessment of patients with stable chest pain, its effect on 5-year clinical outcomes is unknown.
Adamson, Philip D., Berry, Colin, Boon, Nicholas A., Boylan, Heather, Brown, Ammani, Connolly, Eugene, Dweck, Marc R., Farrell, Lesley, Flather, Marcus, Forbes, John, Frood, Alison, Glover, Caroline, Hunter, Amanda, Johnstone, Janet, Lanaghan, Kirsten, Lewis, Stephanie, MacLean, Scott, Mangion, Kenneth, McGlynn, Deborah, McGregor, Lorraine, McLennan, Evonne, Mills, Nicholas L., Mordi, Ify, Murdoch, Laura, Newby, David E., Norrie, John, Paterson, Victoria, Roditi, Giles, Shah, Anoop S.V., Steedman, Tracey, Teenan, Marion, Teyhan, Fiona, The SCOT-HEART Investigators,, Timmis, Adam D., Tzemos, Nikolaos, van Beek, Edwin J.R., Williams, Michelle C., Woodward, Rosie   +37 more
core   +7 more sources

Risk related to pre–diabetes mellitus and diabetes mellitus in heart failure with reduced ejection fraction: insights from prospective comparison of ARNI with ACEI to determine impact on global mortality and morbidity in heart failure trial [PDF]

, 2016
Background—The prevalence of pre–diabetes mellitus and its consequences in patients with heart failure and reduced ejection fraction are not known.
Cardoso, José Silva, Desai, Akshay S., Jhund, Pardeep S., Kristensen, Søren L., Lefkowitz, Martin P., Martinez, Felipe, McMurray, John J.V., Merkely, Bela, Packer, Milton, Preiss, David, Rizkala, Adel R., Rouleau, Jean L., Shi, Victor C., Solomon, Scott D., Squire, Iain, Starling, Randall C., Swedberg, Karl, Zile, Michael R.   +17 more
core   +1 more source

Lower hazard ratio for death in women with cerebral hemorrhage

Acta Neurologica Scandinavica, 2015
The aim of the study was to clarify the hazard ratio for death within 30 days after stroke comparing women to men.
K. Shigematsu, Y. Watanabe, H. Nakano
semanticscholar   +1 more source

Survival after liver transplantation in the United Kingdom and Ireland compared with the United States

, 2007
<b>Background and Aim</b>: Surgical mortality in the US is widely perceived to be superior to that in the UK. However, previous comparisons of surgical outcome in the two countries have often failed to take sufficient account of case-mix or ...
Copley, L.P., Dawwas, M.F., Gimson, A.E., Lewsey, J.D., van der Meulen, J.   +4 more
core   +2 more sources

Perinatal insults and neurodevelopmental disorders may impact Huntington's disease age of diagnosis [PDF]

, 2018
Introduction: The age of diagnosis of Huntington's disease (HD) varies among individuals with the same HTT CAG-repeat expansion size. We investigated whether early-life events, like perinatal insults or neurodevelopmental disorders, influence the ...
Anderson, Dg, Barkhuizen, M, Ferraldeschi, M, Gavilanes, Awd., Kramer, Bw, REGISTRY Investigators of the European Huntington's Disease, Network, Ristori, G, Rodrigues, Fb, Romano, S, Wild, Ej, Winkens, B   +10 more
core   +1 more source