Results 61 to 70 of about 5,710,656 (304)

Network meta-analysis on the log-hazard scale, combining count and hazard ratio statistics accounting for multi-arm trials: A tutorial

open access: yesBMC Medical Research Methodology, 2010
BackgroundData on survival endpoints are usually summarised using either hazard ratio, cumulative number of events, or median survival statistics. Network meta-analysis, an extension of traditional pairwise meta-analysis, is typically based on a single ...
B. Woods, N. Hawkins, D. Scott
semanticscholar   +1 more source

Social context prevents heat hormetic effects against mutagens during fish development

open access: yesFEBS Letters, EarlyView.
This study shows that sublethal heat stress protects fish embryos against ultraviolet radiation, a concept known as ‘hormesis’. However, chemical stress transmission between fish embryos negates this protective effect. By providing evidence for the mechanistic molecular basis of heat stress hormesis and interindividual stress communication, this study ...
Lauric Feugere   +5 more
wiley   +1 more source

Prognostic Factors Associated with Breast Cancer-Specific Survival from 1995 to 2022: A Systematic Review and Meta-Analysis of 1,386,663 Cases from 30 Countries

open access: yesDiseases
Breast cancer is the fifth-ranked cancer globally. Despite early diagnosis and advances in treatment, breast cancer mortality is increasing. This meta-analysis aims to examine all possible prognostic factors that improve/deteriorate breast cancer ...
Hanif Abdul Rahman   +3 more
doaj   +1 more source

Right ventricular free-wall longitudinal speckle tracking strain as a prognostic criterion of adverse outcomes in patients with pulmonary hypertension: a systematic review and meta-analysis

open access: yesРоссийский кардиологический журнал, 2021
The absence of consensus regarding the reference values of right ventricular free wall longitudinal strain (RVFWLS) and its predictive value prompted us to conduct a systematic review and meta-analysis of publications on the predictive role of this ...
E. Z. Golukhova   +6 more
doaj   +1 more source

Hazard Ratio Estimation in Small Samples

open access: yesStatistics in Biopharmaceutical Research, 2018
When comparing survival times between groups in the setting of proportional hazards, the Cox model is typically used for estimation and inference, the latter based on large sample considerations. Mehrotra and Roth introduced a generalized log-rank (GLR) method for better statistical efficiency in estimating relative risk in small samples.
Rengyi Xu   +2 more
openaire   +2 more sources

B cell mechanobiology in health and disease: emerging techniques and insights into therapeutic responses

open access: yesFEBS Letters, EarlyView.
B cells sense external mechanical forces and convert them into biochemical signals through mechanotransduction. Understanding how malignant B cells respond to physical stimuli represents a groundbreaking area of research. This review examines the key mechano‐related molecules and pathways in B lymphocytes, highlights the most relevant techniques to ...
Marta Sampietro   +2 more
wiley   +1 more source

Risk Associations between Air Pollution Exposure and Cardiovascular Diseases: A Residential Retrospective Cohort Study

open access: yesAtmosphere
The population of the Venafro Valley (Southern Italy) faces various type of air pollution problems (industrial facilities, traffic, and biomass combustion).
Elisa Bustaffa   +5 more
doaj   +1 more source

Circulating histones as clinical biomarkers in critically ill conditions

open access: yesFEBS Letters, EarlyView.
Circulating histones are emerging as promising biomarkers in critical illness due to their diagnostic, prognostic, and therapeutic potential. Detection methods such as ELISA and mass spectrometry provide reliable approaches for quantifying histone levels in plasma samples.
José Luis García‐Gimenez   +17 more
wiley   +1 more source

Clinicopathological Presentation, Prognosis, and Overall Survival of Primary Extra Nodal Lymphomas

open access: yesMedical Journal of Dr. D.Y. Patil Vidyapeeth
Introduction: Primary extranodal lymphoma (PENL) originates from extranodal organs or tissues. Approximately 25–40% of NHL arise primarily from sites other than lymph nodes.
Pravinkumar Ghongade   +3 more
doaj   +1 more source

A hazard ratio was estimated by a ratio of median survival times, but with considerable uncertainty [PDF]

open access: yesJournal of Clinical Epidemiology, 2014
To evaluate the empirical concordance between the hazard ratio (HR) and the median ratio (MR) in survival cancer studies.We selected all cancer survival articles from the New England Journal of Medicine published between 2000 and 2010. The qualitative concordance was estimated by the proportion of measured pairs in which the treatment effects for the ...
Cortés Martínez, Jordi   +3 more
openaire   +5 more sources

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