Results 111 to 120 of about 343,520 (257)

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Trouble in Toyland: The 24th Annual Survey of Toy Safety [PDF]

, 2009
Details findings on toys that may pose choking hazards, are excessively loud, or contain lead and phthalates. Offers recommendations for consumers, policy makers, and the Consumer Product Safety Commission.

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Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

Molecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson, Lyanne Delgado‐Coka, Natalia Marchenko, Luisa F. Escobar‐Hoyos, Kenneth R. Shroyer, Alisa Yurovsky, Trey Ideker, Gábor Balázsi, Thomas MacCarthy, Scott Powers   +9 more
wiley   +1 more source

Engineered extracellular vesicles enriched with the miR‐214/199a cluster enhance the efficacy of chemotherapy in ovarian cancer

Molecular Oncology, EarlyView.
Loss of the miR‐214/199a cluster is associated with recurrence in ovarian cancer. Engineered small extracellular vesicles (m214‐sEVs) elevate miR‐214‐3p/miR‐199a‐5p in tumor cells, suppress β‐catenin, TLR4, and YKT6 signaling, reprogram tumor‐derived sEV cargo, reduce chemoresistance and migration, and enhance carboplatin efficacy and survival in ...
Weida Wang, Ayesha Alvero, Yi Qin, Mingjin Wang, Alexandra Fox, Yanfeng Li, Michael Millman, Amy Kemper, Gil Mor, Xian Shuang Liu, Michael Chopp, Zheng Gang Zhang, Yi Zhang   +12 more
wiley   +1 more source

Deciphering transcriptional plasticity in pancreatic ductal adenocarcinoma reveals alterations in sensory neuron innervation

Molecular Oncology, EarlyView.
Pancreatic sensory neurons innervating healthy and PDAC tissue were retrogradely labeled and profiled by single‐cell RNA sequencing. Tumor‐associated innervation showed a dominant neurofilament‐positive subtype, altered mitochondrial gene signatures, and reduced non‐peptidergic neurons.
Elena Genova, Michele Montrone, Uday Rangaswamy, Francesco Diversi, Irene Schiavo, Denise Ferrarini, Roberta Di Florio, Irene Longo, Michele Coscia, Nicola Zamboni, Giorgia Demontis, Lisa Veghini, Vincenzo Corbo, Remo Sanges, Paul Heppenstall   +14 more
wiley   +1 more source

From Microplastics to “Mycoplastics”: Enzymatic Conversion of Oxidized Polystyrene into Humic Acid-like Products

Microplastics
The environmental degradation of plastics results not only in their mechanical fragmentation into microplastics (MPs), but also in polymer main-chain scission processes, causing continuous leaching and/or volatilization of low-molecular-weight species ...
Filippo Petri, Daria Armani, Andrea Corti, Michele Lancia, Antonella Petri, Valter Castelvetro   +5 more
doaj   +1 more source

Livestock-Environment Interaction: Issues and options in Nigeria

Journal of Applied Sciences and Environmental Management, 2010
The demand, production and consumption of livestock products are growing faster than the increase in world population. This development has led to pollution problem caused by the increasing amount of animal waste.
AM Orheruata, JM Omoyakhi
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

The by-products of grain production are an ecological and economic solution to the energy crisis [PDF]

BIO Web of Conferences
The study substantiates that effective handling of by-products of grain production will contribute to ensuring the energy and environmental security of Ukraine.
Shabatura Tetiana, Shevchenko Alisa, Petrenko Olga, Halytskyi Oleksandr   +3 more
doaj   +1 more source

Kecerdasan emosi dalam kalangan pelajar Diploma Pendidikan Lepasan Ijazah (DPLI) Universiti Tun Hussein Onn Malaysia [PDF]

, 2013
Kecerdasan emosi dapat dijadikan sebagai panduan bagi mewujudkan pendidikan yang berkualiti serta sebagai asas pemerolehan ilmu pengetahuan bagi seseorang pendidik dalam menjalankan tugasnya sebagai seorang guru.
Che Ani, Rashida
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