Results 121 to 130 of about 343,520 (257)
NKCC1: A key regulator of glioblastoma progression
Molecular Oncology, EarlyView.Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen +5 more
wiley +1 more source
Hazardous Waits: CPSC Lets Crucial Time Pass Before Warning Public About Dangerous Products [PDF]
, 2008 Despite a law requiring manufacturers to provide the Consumer Product Safety Commission (CPSC) with "immediate" notification of dangerous products, the agency typically delays nearly seven months after learning of dangerous, defective products before ...
Taylor Lincoln
core
Molecular Oncology, EarlyView.Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen +9 more
wiley +1 more source
A Review on the Green Synthesis of Silver Nanoparticles and Their Morphologies Studied via TEM
Advances in Materials Science and Engineering, 2015 Silver has been recognized as a nontoxic, safe inorganic antibacterial/antifungal agent used for centuries. Silver demonstrates a very high potential in a wide range of biological applications, more particularly in the form of nanoparticles ...
Protima Rauwel +3 more
doaj +1 more source
Dispersants and Seafood Safety Assessment of the potential impact of Corexit® oil dispersants on seafood safety [PDF]
, 2011 The April 20, 2010 explosion and subsequent sinking of the Deepwater Horizon oil production platform (DWH) resulted in the largest oil spill in U.S. history.
Dickey, Robert W., Dickhoff, Walton W.
core +1 more source
Molecular Oncology, EarlyView.A urine‐based digital PCR assay targeting two hotspot TERT promoter variants detected bladder cancer with high sensitivity and no false positives in this case–control cohort. The streamlined AbsoluteQ workflow outperformed Sanger sequencing and supports non‐invasive molecular testing for bladder cancer detection.
Anna Nykel +12 more
wiley +1 more source
Loss of IGF‐1R impairs DNA‐PKcs recruitment to chromatin leading to defective end‐joining
Molecular Oncology, EarlyView.IGF‐1R promotes radioresistance by facilitating DNA‐PKcs recruitment to chromatin, enabling non‐homologous end‐joining (NHEJ) repair of double‐strand breaks. Inhibition or loss of IGF‐1R disrupts this recruitment to damage sites, driving compensatory reliance on microhomology‐mediated end‐joining (MMEJ) repair.
Matthew O. Ellis +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.Chemoresistance in bladder cancer: Macrophage recruitment associated with CXCL1, CXCL5 and CXCL8 expression is characteristic of Gemcitabine/Cisplatin (Gem/Cis) Non‐Responder tumors (right side) while Responder tumors did not show substantial tumor‐stromal crosstalk (left side). All biological icons are attributed to Bioicons: carcinoma, cancerous‐cell‐
Sophie Leypold +11 more
wiley +1 more source
Practical small-scale explosive seam welding [PDF]
, 1983 A small-scale explosive seam welding process has been developed that can significantly contribute to remote metal joining operations under hazardous or inaccessible conditions, such as nuclear reactor repair and assembly of structure in space. This paper
Bement, L. J.
core +2 more sources
Treatment of metal-laden hazardous wastes with advanced clean coal technology by-products. Quarterly report, February--May 1995 [PDF]
, 1995 This report describes the activities of the project team during the reporting period. The principal work has focused upon the laboratory treatment of six wastes with three by-products and the evaluation of the stability of the resulting eighteen materials. Other efforts during the third quarter have been directed toward completion of the collection and
openaire +2 more sources