Results 61 to 70 of about 71,793 (263)

Trace Element Content of Polyfloral Honey and Beeswax from the Vicinity of Non-Ferrous Metal Plant

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology, 2019
Bees and their products occupy an important place in the trophic chain “toxicant-soil-plant-bee-bee product-man”, so it has been suggested that bees and bee products should be considered as not a costly method for monitoring of the environmental ...
Bogdan NIKOLOV, Irena GOLUBINOVA, Plamen MARINOV-SERAFIMOV, Slaveya PETROVA   +3 more
doaj   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

FEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto, Masatomo So, Ayako Furukawa, Kenji Sugase   +3 more
wiley   +1 more source

Green approach for the synthesis of some new α, β-unsaturated ketimines under water suspension

Orbital: The Electronic Journal of Chemistry, 2012
An environmentally benign and efficient synthesis of some a,ß-unsaturated ketimines from new 2-hydroxychalcone and different aromatic amines under water suspension.
Subash M. Lonkar, Shyam S. Mokle, Archana Y. Vibhute, Yeshwant B. Vibhute   +3 more
doaj   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

An unexpected alternative viologen electron mediator site in tungsten‐containing formate dehydrogenase

FEBS Letters, EarlyView.
An unexpected alternative interaction site for ethyl viologen was identified in formate dehydrogenase 1 from Methylorubrum extorquens. Combined mutagenesis, kinetic analysis, and docking revealed that aromatic residues near an iron–sulfur cluster enable flavin mononucleotide‐independent electron transfer, offering a framework for engineering improved ...
Eleni G. Poloniataki, Yong Hwan Kim
wiley   +1 more source

Microbiome−host proteostasis crosstalk—An emerging perspective on mechanisms and interventions toward healthy longevity

FEBS Letters, EarlyView.
Proteostasis and the gut microbiota play a key role in shaping host physiology. Microbiota‐derived metabolites, vitamins, and RNA modulate host proteostasis. Findings from model systems, including C. elegans, indicate microbes can either stabilize or disrupt host proteostasis.
Abhishek Anil Dubey, Maria Ermolaeva
wiley   +1 more source

Classification of substances by health hazard using deep neural networks and molecular electron densities

Journal of Cheminformatics
In this paper we present a method that allows leveraging 3D electron density information to train a deep neural network pipeline to segment regions of high, medium and low electronegativity and classify substances as health hazardous or non-hazardous. We
Satnam Singh, Gina Zeh, Jessica Freiherr, Thilo Bauer, Isik Türkmen, Andreas T. Grasskamp   +5 more
doaj   +1 more source

Addressing the toxic chemicals problem in plastics recycling

Cambridge Prisms: Plastics
Ongoing policy negotiations, such as the negotiations for a future global plastics treaty, include calls for increased recycling of plastics. However, before recycling of plastics can be considered a safe practice, the flaws in today’s systems must be ...
Bethanie Carney Almroth, Eric Carmona, Nnaemeka Chukwuone, Tridibesh Dey, Daniel Slunge, Thomas Backhaus, Therese Karlsson   +6 more
doaj   +1 more source

PEG-400 as an efficient and recyclable reaction medium for the synthesis of polyhydroquinolines via Hantzsch reaction

Orbital: The Electronic Journal of Chemistry, 2013
Polyhydroquinoline derivatives have been prepared efficiently in a one-pot synthesis via Hantzsch condensation using PEG-400 as reaction medium. The present method does not involve any hazardous organic solvents or toxic catalysts.
Shitole Nana Vikram, Balasaheb V. Shitole, Gopal K. Kakde, Murlidhar S. Shingare   +3 more
doaj   +1 more source

EAHP's survey on hazardous medicinal products. [PDF]

Eur J Hosp Pharm, 2021
Kohl S.
europepmc   +1 more source