Results 81 to 90 of about 343,520 (257)

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

Molecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice, Jose I. Lopez, Aitziber Ugalde‐Olano, Maite Zufiaurre, Ianire Astobiza, Natalia Martin‐Martin, Laura Bozal‐Basterra, Saioa Garcia‐Longarte, Amaia Zabala‐Letona, Sofia Rey, Aida Santos‐Martin, Miguel Unda, Ana Loizaga‐Iriarte, Mariona Graupera, Paolo Nuciforo, Arkaitz Carracedo, Isabel Mendizabal   +16 more
wiley   +1 more source

Study protocol for the Korean Human Exposure Safety Survey (KoHESS): a national biomonitoring program for food and consumer product safety [PDF]

Epidemiology and Health
This protocol paper describes the design and methodology of the Korean Human Exposure Safety Survey (KoHESS), a three-year national biomonitoring program (2023-2025).
Hyeon-Jeong Lim, Sang-Yong Eom, Sun-Haeng Choi, Seonmi Hong, Byung-Sun Choi, Young-Seoub Hong, Kwan Lee, Won-Ju Park, Jae-Seok Song, Nam-Jun Kim, Hyo-Jeong Hwang, Rihwa Choi, Hosub Im, Youn-Seok Kang, Hye-Young Lee, Mi-Ran Kim, Hyunjin Son, Yong-Dae Kim   +17 more
doaj   +1 more source

The Regulation and Development of Bioremediation [PDF]

, 1996
The authors describe how federal statutes regulating hazardous wastes create both incentives and disincentives for exploiting the large potential of bioremediation.
Connolly, D. Michael, Timian, Susan J.
core   +1 more source

Hazard and risk assessment for indirect potable reuse schemes: An approach for use in developing Water Safety Plans [PDF]

, 2010
This is the post-print version of the final paper published in Water Research. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and ...
Angelina Dominguez-Chicas, Asano, Bannerman, Casani, Crook, Crook, Davison, Defra, Del Pino, Dyck, EC, Environment Agency, Gurr, Hamilton, Kasprzyk-Hordern, Mark D. Scrimshaw, Metcalf, NRC, NRMMC, NRMMC, NRMMC, Rodriguez, Rodriguez, Rodriguez, Singapore Public Utilities Board (PUB), WHO, WHO, Yuan   +27 more
core   +1 more source

Effect of incineration, co‐incineration and combustion on TSE hazards in category 1 animal by‐products

EFSA Journal
Abstract The European Commission requested EFSA to assess the effect of incineration, co‐incineration and combustion of Category 1 animal by‐products (ABP) on the BSE/TSE hazards in ash resulting from these treatments. The presence of residual TSE hazards is assessed by detection of prion infectivity or seeding activity.
EFSA Panel on Biological Hazards (BIOHAZ), Allende, Ana, Alvarez-Ordóñez, Avelino, Bortolaia, Valeria, Bover-Cid, Sara, De Cesare, Alessandra, Dohmen, Wietske, Guillier, Laurent, Herman, Lieve Maria, Jacxsens, Liesbeth, Mughini-Gras, Lapo, Nauta, Maarten, Ottoson, Jakob, Peixe, Luisa, Perez-Rodriguez, Fernando, Skandamis, Panagiotis, Suffredini, Elisabetta, Andreoletti, Olivier, Béringue, Vincent, Griffin, John, Simmons, Marion, Kryemadhi, Kamela, Lanfranchi, Barbara, Ortiz-Pelaez, Angel, Nonno, Romolo   +24 more
openaire   +4 more sources

Dammarenediol II enhances etoposide‐induced apoptosis by targeting O‐GlcNAc transferase and Akt/GSK3β/mTOR signaling in liver cancer

Molecular Oncology, EarlyView.
Etoposide induces DNA damage, activating p53‐dependent apoptosis via caspase‐3/7, which cleaves PARP1. Dammarenediol II enhances this apoptotic pathway by suppressing O‐GlcNAc transferase activity, further decreasing O‐GlcNAcylation. The reduction in O‐GlcNAc levels boosts p53‐driven apoptosis and influences the Akt/GSK3β/mTOR signaling pathway ...
Jaehoon Lee, Byung‐Cheol Han, Gi‐Bang Koo, Jihye Park, Mijin Kwon, Young Bin Park, Jae‐Mun Choi, Seung‐Ho Lee, Sangho Roh   +8 more
wiley   +1 more source

Trace Element Content of Polyfloral Honey and Beeswax from the Vicinity of Non-Ferrous Metal Plant

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca: Food Science and Technology, 2019
Bees and their products occupy an important place in the trophic chain “toxicant-soil-plant-bee-bee product-man”, so it has been suggested that bees and bee products should be considered as not a costly method for monitoring of the environmental ...
Bogdan NIKOLOV, Irena GOLUBINOVA, Plamen MARINOV-SERAFIMOV, Slaveya PETROVA   +3 more
doaj   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Green approach for the synthesis of some new α, β-unsaturated ketimines under water suspension

Orbital: The Electronic Journal of Chemistry, 2012
An environmentally benign and efficient synthesis of some a,ß-unsaturated ketimines from new 2-hydroxychalcone and different aromatic amines under water suspension.
Subash M. Lonkar, Shyam S. Mokle, Archana Y. Vibhute, Yeshwant B. Vibhute   +3 more
doaj   +1 more source

Guidelines and Methods for Conducting Porperty Transfer Site Histories [PDF]

, 1990
HWRIC Project 90-077NTIS PB91 ...
Colten, Craig E., Mulville-Friel, Diane
core