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Comparative effectiveness of tenofovir versus entecavir combined with peginterferon Alfa-2b for functional cure in HBeAg-negative chronic hepatitis B: a propensity score-matched analysis. [PDF]

BMC Infect Dis
Wang PP, Wu HS, Deng WJ, Wu Y, Zhang Y, Gao ZL, Mo ZS.   +6 more
europepmc   +1 more source

Chronic Hepatitis B: Current Management and Future Directions. [PDF]

Diseases
Ertugrul H, Ekiz E, Islak Mutcali S, Tahan V, Daglilar E.   +4 more
europepmc   +1 more source

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Patients with interferon-induced HBeAg seroconversion have a higher risk of HBV reactivation and HBeAg seroreversion

Hepatology International, 2014
It remains unclear whether chronic hepatitis B patients who undergo interferon (IFN)-induced hepatitis B e antigen (HBeAg) seroconversion have a higher risk of hepatitis B virus (HBV) reactivation and HBeAg seroreversion than those with spontaneous HBeAg seroconversion.A total of 80 and 251 non-cirrhotic patients with interferon-induced and spontaneous
Chien-Hung, Chen, Sheng-Nan, Lu, Chuan-Mo, Lee, Chao-Hung, Hung, Jing-Houng, Wang, Tsung-Hui, Hu   +5 more
openaire   +2 more sources

Quantitative serum HBsAg and HBeAg are strong predictors of sustained HBeAg seroconversion to pegylated interferon alfa‐2b in HBeAg‐positive patients

Journal of Gastroenterology and Hepatology, 2010
AbstractBackground and Aim:  To evaluate the usefulness of quantitative hepatitis B surface antigen (HBsAg) and hepatitis B e antigen (HBeAg) for predicting HBeAg seroconversion in chronic hepatitis B patients treated with conventional interferon (IFN) alfa‐2b or PegIFN alfa‐2b.Methods:  Fifty‐eight patients were enrolled; 29 for the training group and
Hui, Ma, Rui-Feng, Yang, Lai, Wei
openaire   +2 more sources

Predictive Factors for Early HBeAg Seroconversion in Acute Exacerbation of Patients With HBeAg-Positive Chronic Hepatitis B

Gastroenterology, 2009
This study aimed to identify the predictors for early hepatitis B e antigen (HBeAg) seroconversion following acute exacerbation (AE) in patients with HBeAg-positive chronic hepatitis B (CHB).A total of 151 patients with HBeAg-positive CHB and AE were consecutively enrolled. AE was defined as an elevation of alanine aminotransferase level to more than 5
Hyoung Su, Kim, Ha Jung, Kim, Woon Geon, Shin, Kyung Ho, Kim, Jin Heon, Lee, Hak Yang, Kim, Myoung Kuk, Jang   +6 more
openaire   +2 more sources

Effect of virologic response on posttreatment durability of lamivudine-induced HBeAg seroconversion

Journal of Hepatology, 2001
Lamivudine‐induced HBeAg seroconversion may not be durable in Korean patients with hepatitis B virus (HBV) infection. It is unknown whether virological response during lamivudine treatment affects the post‐treatment outcome. We retrospectively analysed 124 consecutive HBeAg‐positive chronic hepatitis B (CHB) patients treated with lamivudine. Lamivudine
K M, Lee, Sung Won, Cho, S W, Kim, H J, Kim, K B, Hahm, J H, Kim   +5 more
openaire   +3 more sources

Prediction of spontaneous HBeAg seroconversion in HBeAg‐positive chronic hepatitis B patients during the immune clearance phase

Journal of Medical Virology, 2014
Spontaneous hepatitis B virus (HBV) e antigen (HBeAg) seroconversion is associated with reduced risk of liver‐related complications, but is poorly understood. In this study, 113 chronic hepatitis B patients in the immune active HBeAg‐positive phase were followed up for 76 weeks.
Guangjun, Song, Huiying, Rao, Bo, Feng, Lai, Wei   +3 more
openaire   +2 more sources

Long‐term effect of maternal HBeAg on delayed HBeAg seroconversion in offspring with chronic hepatitis B infection

Liver International, 2011
Abstract Background and aims: This cohort study investigated the long‐term effect of maternal hepatitis B virus (HBV) sero‐status on the spontaneous HBeAg seroconversion in offspring with chronic HBV infection. Methods: A total of 185 HBeAg‐positive chronic HBV‐infected children, with maternal HBV seromarkers checked, were ...
Yu-Ru, Tseng, Jia-Feng, Wu, Yen-Hsuan, Ni, Huey-Ling, Chen, Chih-Cheng, Chen, Wan-Hsin, Wen, Hong-Yuan, Hsu, Mei-Hwei, Chang   +7 more
openaire   +2 more sources