Results 41 to 50 of about 7,551 (201)

Hepatitis B surface antigen quantification at hepatitis B e antigen seroconversion predicts virological relapse after the cessation of entecavir treatment in hepatitis B e antigen-positive patients

open access: yesInternational Journal of Infectious Diseases, 2016
Objectives: To assess off-treatment virological relapse rates and to determine the role of hepatitis B surface antigen (HBsAg) quantification in predicting virological relapse after stopping entecavir (ETV) treatment in patients with hepatitis B e ...
Yuan-wang Qiu   +11 more
doaj   +1 more source

O-22 DIFFERENTIAL MUTATION PATTERN ASSOCIATED WITH HEPATITIS B E ANTIGEN SEROCONVERSION BETWEEN SUBGENOTYPE F1b CLUSTERS: POTENTIAL ROLE IN PATHOGENESIS

open access: yesAnnals of Hepatology, 2023
Introduction and Objectives: Two clusters of the subgenotype F1b (basal and cosmopolitan) have recently been described. The basal cluster has been associated with the early occurrence of hepatocellular carcinoma in chronically infected patients from ...
Micaela Martínez   +4 more
doaj   +1 more source

Relative predictive factors for hepatocellular carcinoma after HBeAg seroconversion in HBV infection

open access: yesWorld Journal of Gastroenterology, 2005
To determine the predictive factors for hepatocellular carcinoma (HCC) development in patients after spontaneous or therapeutic HBeAg seroconversion.In 48 patients who seroconverted to anti-HBe positive during follow-up, the background factors for HCC development were analyzed.HCC was developed in six patients during follow-up (average follow-up after ...
Kazumoto, Murata   +3 more
openaire   +2 more sources

Intrahepatic HBV DNA as a predictor of antivirus treatment efficacy in HBeAg-positive chronic hepatitis B patients [PDF]

open access: yes, 2007
AIM: To evaluate the effect of antiviral agents on intrahepatic HBV DNA in HBeAg-positive chronic hepatitis B patients. METHODS: Seventy-one patients received treatment with lamivudine, interferon alpha (IFN-alpha 2b) or sequential therapy with ...
Chen, Xin-Yue   +10 more
core   +1 more source

Clinical Analysis of Polyethylene Glycol Interferon-α Treatment in 155 Hepatitis B e Antigen (HBeAg)-Positive Chronic Hepatitis B (CHB) Patients

open access: yesAnnals of Hepatology, 2017
Purpose: This study aims to investigate the antiviral effect of polyethylene glycol (PEG)-interferon α-2a and PEG-interferon α-2b treatment on hepatitis B e antigen (HBeAg)-positive chronic hepatitis B (CHB) at the 48th week of treatment and the 24th and
Xin Luo   +4 more
doaj   +1 more source

Relationship between the development of precore and core promoter mutations and hepatitis B e antigen seroconversion in patients with chronic hepatitis B virus [PDF]

open access: yes, 2002
Chinese patients with chronic hepatitis B virus (332 with and 44 without cirrhosis-related complications) were studied. Fifty percent of patients
Chan, AOO   +8 more
core   +1 more source

Optimization of adefovir therapy in chronic hepatitis B according to baseline predictors and on-treatment HBV DNA: a 5-Year prospective study

open access: yesVirology Journal, 2011
Background Adefovir Dipivoxil (ADV) is an important agent to suppress hepatitis B virus (HBV) replication with suboptimal effect on virological and serological response.
Zhang Jing   +5 more
doaj   +1 more source

Chronic hepatitis B: whom to treat and for how long? Propositions, challenges, and future directions [PDF]

open access: yes, 2010
Recent guidelines of the American Association for the Study of Liver Diseases, the European Association for the Study of the Liver, and the Asian Pacific Association for the Study of the Liver 2008 update of the "Asian-Pacific consensus statement on the ...
Sang Hoon Ahn   +100 more
core   +3 more sources

Potential Efficacy of Pegylated Interferon-α and a Nucleos(t)ide Analogue as Combination Therapy for HBeAg-Positive Chronic Hepatitis B

open access: yesGut and Liver, 2016
Background/AimsDespite the potent suppression of the hepatitis B virus with modern antiviral agents, only a minority of HBeAg-positive patients achieve hepatitis B e antigen seroconversion.
Chung-Il Wi   +4 more
doaj   +1 more source

Effects of dyslipidemia on E antigen seroconversion of patients with chronic hepatitis B treated by nucleoside (acid) analogs

open access: yesLipids in Health and Disease, 2021
Background The prevalence of dyslipidemia in China is increasing annually. Current studies suggest that dyslipidemia affects the antiviral efficacy of hepatitis C virus (HCV) therapies, while recent studies suggest that serum lipids influence the ...
Ziqiang Xia   +6 more
doaj   +1 more source

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